(Q46336917)

English

Configurational assignment of secondary hydroxyl groups and methyl branches in polyketide natural products through bioinformatic analysis of the ketoreductase domain

scientific article published on 10 April 2013

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

21 December 2017

http://europepmc.org/abstract/MED/23576424

Configurational assignment of secondary hydroxyl groups and methyl branches in polyketide natural products through bioinformatic analysis of the ketoreductase domain (English)

1 reference

Europe PubMed Central

PubMed publication ID

21 December 2017

http://europepmc.org/abstract/MED/23576424

1 reference

based on heuristic

inferred from title

natural product

1 reference

based on heuristic

inferred from title

author name string

Andreas Kitsche

1

1 reference

Europe PubMed Central

PubMed publication ID

21 December 2017

http://europepmc.org/abstract/MED/23576424

Markus Kalesse

2

1 reference

Europe PubMed Central

PubMed publication ID

21 December 2017

http://europepmc.org/abstract/MED/23576424

publication date

10 April 2013

1 reference

Europe PubMed Central

PubMed publication ID

21 December 2017

http://europepmc.org/abstract/MED/23576424

1 reference

Europe PubMed Central

PubMed publication ID

21 December 2017

http://europepmc.org/abstract/MED/23576424

14

1 reference

Europe PubMed Central

PubMed publication ID

21 December 2017

http://europepmc.org/abstract/MED/23576424

7

1 reference

Europe PubMed Central

PubMed publication ID

21 December 2017

http://europepmc.org/abstract/MED/23576424

851-861

1 reference

Europe PubMed Central

PubMed publication ID

21 December 2017

http://europepmc.org/abstract/MED/23576424

New methods for stereochemical determination of complex polyketides: configurational assignment of novel metabolites from myxobacteria

1 reference

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Stereochemical determination and complex biosynthetic assembly of etnangien, a highly potent RNA polymerase inhibitor from the myxobacterium Sorangium cellulosum.

1 reference

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1 reference

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21 January 2018

A model of structure and catalysis for ketoreductase domains in modular polyketide synthases

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.201300063

21 January 2018

Conserved amino acid residues correlating with ketoreductase stereospecificity in modular polyketide synthases

1 reference

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Amphotericin biosynthesis in Streptomyces nodosus: deductions from analysis of polyketide synthase and late genes

1 reference

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Biosynthesis of the polyene antifungal antibiotic nystatin in Streptomyces noursei ATCC 11455: analysis of the gene cluster and deduction of the biosynthetic pathway.

1 reference

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21 January 2018

Prediction and manipulation of the stereochemistry of enoylreduction in modular polyketide synthases

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.201300063

21 January 2018

Predicting the nature and timing of epimerisation on a modular polyketide synthase.

1 reference

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21 January 2018

The structure of a ketoreductase determines the organization of the beta-carbon processing enzymes of modular polyketide synthases.

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.201300063

21 January 2018

The biochemical basis for stereochemical control in polyketide biosynthesis

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.201300063

21 January 2018

Insights into the stereospecificity of ketoreduction in a modular polyketide synthase

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.201300063

21 January 2018

Directed mutagenesis alters the stereochemistry of catalysis by isolated ketoreductase domains from the erythromycin polyketide synthase

1 reference

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21 January 2018

Broad substrate specificity of ketoreductases derived from modular polyketide synthases.

1 reference

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21 January 2018

Ketoreduction in mycolactone biosynthesis: insight into substrate specificity and stereocontrol from studies of discrete ketoreductase domains in vitro

1 reference

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21 January 2018

Stereochemistry of catalysis by the ketoreductase activity in the first extension module of the erythromycin polyketide synthase

1 reference

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21 January 2018

Profile hidden Markov models

1 reference

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21 January 2018

Estimation and efficient computation of the true probability of recurrence of short linear protein sequence motifs in unrelated proteins

1 reference

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21 January 2018

DoBISCUIT: a database of secondary metabolite biosynthetic gene clusters

1 reference

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21 January 2018

Fast, scalable generation of high-quality protein multiple sequence alignments using Clustal Omega

1 reference

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21 January 2018

A new bioinformatics analysis tools framework at EMBL-EBI.

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.201300063

21 January 2018

HMM-ModE--improved classification using profile hidden Markov models by optimising the discrimination threshold and modifying emission probabilities with negative training sequences

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.201300063

21 January 2018

Analysis and prediction of functional sub-types from protein sequence alignments.

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.201300063

21 January 2018

The Molecular Basis of Celmer's Rules: The Stereochemistry of the Condensation Step in Chain Extension on the Erythromycin Polyketide Synthase†

1 reference

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21 January 2018

Identifiers

10.1002/CBIC.201300063

1 reference

Europe PubMed Central

PubMed publication ID

21 December 2017

http://europepmc.org/abstract/MED/23576424

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

21 December 2017

http://europepmc.org/abstract/MED/23576424

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