(Q46337180)

21 December 2017

title

Biochemical characterization of the minimal polyketide synthase domains in the lovastatin nonaketide synthase LovB. (English)

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21 December 2017

author name string

Suzanne M Ma

series ordinal

1

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21 December 2017

Yi Tang

series ordinal

2

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21 December 2017

language of work or name

English

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publication date

27 April 2007

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21 December 2017

published in

FEBS Journal

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21 December 2017

volume

274

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21 December 2017

page(s)

2854-2864

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21 December 2017

issue

11

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21 December 2017

Lovastatin and beyond: the history of the HMG-CoA reductase inhibitors

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Lovastatin biosynthesis in Aspergillus terreus: characterization of blocked mutants, enzyme activities and a multifunctional polyketide synthase gene

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Modular organization of genes required for complex polyketide biosynthesis

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An iterative type I polyketide synthase PKSN catalyzes synthesis of the decaketide alternapyrone with regio-specific octa-methylation

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Developing a genetic system for functional manipulations of FUM1, a polyketide synthase gene for the biosynthesis of fumonisins in Fusarium verticillioides.

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Production of dihydroisocoumarins in Fusarium verticillioides by swapping ketosynthase domain of the fungal iterative polyketide synthase Fum1p with that of lovastatin diketide synthase.

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Expression in Escherichia coli and refolding of the malonyl-/acetyltransferase domain of the multifunctional animal fatty acid synthase.

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The 2.7-Angstrom crystal structure of a 194-kDa homodimeric fragment of the 6-deoxyerythronolide B synthase.

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Reconstituting modular activity from separated domains of 6-deoxyerythronolide B synthase

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The structure of a ketoreductase determines the organization of the beta-carbon processing enzymes of modular polyketide synthases.

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Extender unit and acyl carrier protein specificity of ketosynthase domains of the 6-deoxyerythronolide B synthase

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Insights into channel architecture and substrate specificity from crystal structures of two macrocycle-forming thioesterases of modular polyketide synthases

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Crystal structure of the macrocycle-forming thioesterase domain of the erythromycin polyketide synthase: Versatility from a unique substrate channel

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Biosynthesis of complex polyketides in a metabolically engineered strain of E. coli

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Ketosynthases in the initiation and elongation modules of aromatic polyketide synthases have orthogonal acyl carrier protein specificity

21 January 2018

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Solution structure and dynamics of oxytetracycline polyketide synthase acyl carrier protein from Streptomyces rimosus

21 January 2018

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Characterization of the malonyl-/acetyltransacylase domain of the multifunctional animal fatty acid synthase by expression in Escherichia coli and refolding in vitro

21 January 2018

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21 January 2018

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Catalysis, specificity, and ACP docking site of Streptomyces coelicolor malonyl-CoA:ACP transacylase

21 January 2018

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The Escherichia coli malonyl-CoA:acyl carrier protein transacylase at 1.5-A resolution. Crystal structure of a fatty acid synthase component

21 January 2018

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Alteration of the substrate specificity of the malonyl-CoA/acetyl-CoA:acyl carrier protein S-acyltransferase domain of the multifunctional fatty acid synthase by mutation of a single arginine residue

21 January 2018

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Malonyl-coenzyme A:acyl carrier protein acyltransferase of Streptomyces glaucescens: a possible link between fatty acid and polyketide biosynthesis.

21 January 2018

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Characterization of the interthiol acyltransferase reaction catalyzed by the beta-ketoacyl synthase domain of the animal fatty acid synthase

21 January 2018

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Structure of the complex between the antibiotic cerulenin and its target, beta-ketoacyl-acyl carrier protein synthase

21 January 2018

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10.1111/J.1742-4658.2007.05818.X

21 January 2018

Identifiers

DOI

1 reference

21 December 2017

PubMed ID

17466016

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21 December 2017