(Q46352537)

21 December 2017

title

Modulation of the rate of peptidyl transfer on the ribosome by the nature of substrates (English)

1 reference

21 December 2017

author

Malte Beringer

3

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21 December 2017

Marina Rodnina

4

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21 December 2017

author name string

Ingo Wohlgemuth

1

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21 December 2017

Sibylle Brenner

2

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21 December 2017

language of work or name

English

0 references

publication date

22 September 2008

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21 December 2017

Journal of Biological Chemistry

number of pages

7

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based on heuristic

inferred from page(s)

published in

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21 December 2017

volume

283

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21 December 2017

issue

47

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21 December 2017

page(s)

32229-32235

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21 December 2017

The complete atomic structure of the large ribosomal subunit at 2.4 A resolution

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An induced-fit mechanism to promote peptide bond formation and exclude hydrolysis of peptidyl-tRNA.

21 January 2018

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The ribosome as an entropy trap

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The rate enhancement produced by the ribosome: an improved model

21 January 2018

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Mechanism of peptide bond synthesis on the ribosome

21 January 2018

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The ribosomal peptidyl transferase

21 January 2018

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Essential mechanisms in the catalysis of peptide bond formation on the ribosome.

21 January 2018

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Efficient 50S ribosome-catalyzed peptide bond synthesis with an aminoacyl minihelix.

21 January 2018

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Important contribution to catalysis of peptide bond formation by a single ionizing group within the ribosome.

21 January 2018

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Rapid peptide bond formation on isolated 50S ribosomal subunits

21 January 2018

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The puromycin route to assess stereo- and regiochemical constraints on peptide bond formation in eukaryotic ribosomes

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An uncharged amine in the transition state of the ribosomal peptidyl transfer reaction

21 January 2018

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Ribosome-catalyzed peptidyl transfer: substrate specificity at the P-site

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Molecular mechanism of drug-dependent ribosome stalling

21 January 2018

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Peptidyl-prolyl-tRNA at the ribosomal P-site reacts poorly with puromycin

21 January 2018

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Changes produced by bound tryptophan in the ribosome peptidyl transferase center in response to TnaC, a nascent leader peptide

21 January 2018

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Ribosomal features essential for tna operon induction: tryptophan binding at the peptidyl transferase center

21 January 2018

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Proline residues at the C terminus of nascent chains induce SsrA tagging during translation termination

21 January 2018

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GTP consumption of elongation factor Tu during translation of heteropolymeric mRNAs

21 January 2018

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Selection of the mRNA translation initiation region by Escherichia coli ribosomes

21 January 2018

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Single-step purification of specific tRNAs by hydrophobic tagging.

21 January 2018

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An in vitro evolved precursor tRNA with aminoacylation activity

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Using a solid-phase ribozyme aminoacylation system to reprogram the genetic code

21 January 2018

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A ribozyme exclusively aminoacylates the 3'-hydroxyl group of the tRNA terminal adenosine

21 January 2018

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Nucleoside triphosphate regeneration decreases the frequency of translation errors

21 January 2018

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Importance of tRNA interactions with 23S rRNA for peptide bond formation on the ribosome: studies with substrate analogs

21 January 2018

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The kinetics of ribosomal peptidyl transfer revisited

21 January 2018

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Uniform binding of aminoacyl-tRNAs to elongation factor Tu by thermodynamic compensation

21 January 2018

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Uniform binding of aminoacylated transfer RNAs to the ribosomal A and P sites.

21 January 2018

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Complete kinetic mechanism of elongation factor Tu-dependent binding of aminoacyl-tRNA to the A site of the E. coli ribosome

21 January 2018

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Relation between aminoacyl-tRNA stability and the fixed amino acid

21 January 2018

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Effects of amino acid structure, ionic strength, and magnesium ion concentration on rates of nonenzymic hydrolysis of aminoacyl transfer ribonucleic acid.

21 January 2018

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A base pair between tRNA and 23S rRNA in the peptidyl transferase centre of the ribosome

21 January 2018

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The structural basis of ribosome activity in peptide bond synthesis

21 January 2018

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The hybrid state of tRNA binding is an authentic translation elongation intermediate

21 January 2018

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Structural basis of the ribosomal machinery for peptide bond formation, translocation, and nascent chain progression

21 January 2018

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The use of a steric parameter (Y gamma) in QSAR calculations for peptide hormones.

21 January 2018

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Rate constants for peptide p-nitrophenyl ester coupling reactions in dimethylformamide. A model for steric interactions in the peptide bond forming transition state.

21 January 2018

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Substrate-assisted catalysis of peptide bond formation by the ribosome

21 January 2018

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The mechanism of the aminolysis of acetate esters.

21 January 2018

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Development of ERK Activity Sensor, an in vitro, FRET-based sensor of Extracellular Regulated Kinase activity.

21 January 2018

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Impact of cis-proline analogs on peptide conformation

21 January 2018

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Influence of the last amino acid in the nascent peptide on EF-Tu during decoding.

21 January 2018

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The mechanism of tryptophan induction of tryptophanase operon expression: tryptophan inhibits release factor-mediated cleavage of TnaC-peptidyl-tRNA(Pro).

21 January 2018

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Prolyl-tRNA(Pro) in the A-site of SecM-arrested ribosomes inhibits the recruitment of transfer-messenger RNA.

21 January 2018

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Genetically encoded but nonpolypeptide prolyl-tRNA functions in the A site for SecM-mediated ribosomal stall.

21 January 2018

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Translation arrest requires two-way communication between a nascent polypeptide and the ribosome.

21 January 2018

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On the structural basis of peptide-bond formation and antibiotic resistance from atomic structures of the large ribosomal subunit

21 January 2018

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Antibiotics targeting ribosomes: resistance, selectivity, synergism and cellular regulation

21 January 2018

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The ribosome's response to codon-anticodon mismatches.

21 January 2018

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An active role for tRNA in decoding beyond codon:anticodon pairing

21 January 2018

1 reference

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Halting a cellular production line: responses to ribosomal pausing during translation

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.M805316200

1 reference

21 December 2017

1 reference

21 December 2017