(Q46375245)

21 December 2017

title

Intrinsic differences between the catalytic properties of the oncogenic NUP214-ABL1 and BCR-ABL1 fusion protein kinases (English)

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21 December 2017

author

Kim De Keersmaecker

1

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21 December 2017

Jan Cools

3

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21 December 2017

Giulio Superti-Furga

4

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21 December 2017

Oliver Hantschel

5

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21 December 2017

author name string

M Versele

2

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21 December 2017

publication date

11 September 2008

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21 December 2017

published in

Leukemia

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21 December 2017

volume

22

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21 December 2017

issue

12

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21 December 2017

page(s)

2208-2216

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21 December 2017

A coiled-coil oligomerization domain of Bcr is essential for the transforming function of Bcr-Abl oncoproteins

cites work

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2008.242

Oligomerization of the ABL tyrosine kinase by the Ets protein TEL in human leukemia

21 January 2018

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Protein tyrosine kinases: autoregulation and small-molecule inhibition

21 January 2018

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7 January 2021

Global survey of phosphotyrosine signaling identifies oncogenic kinases in lung cancer

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7 January 2021

The conformational plasticity of protein kinases

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7 January 2021

Regulation of the c-Abl and Bcr-Abl tyrosine kinases

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https://api.crossref.org/works/10.1038%2FLEU.2008.242

7 January 2021

Tyrosine kinase fusion genes in chronic myeloproliferative diseases.

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7 January 2021

Chronic myeloproliferative disorders: a tyrosine kinase tale.

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7 January 2021

The BCR-ABL story: bench to bedside and back

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https://api.crossref.org/works/10.1038%2FLEU.2008.242

7 January 2021

Induction of chronic myelogenous leukemia in mice by the P210bcr/abl gene of the Philadelphia chromosome

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2008.242

7 January 2021

The P190, P210, and P230 forms of the BCR/ABL oncogene induce a similar chronic myeloid leukemia-like syndrome in mice but have different lymphoid leukemogenic activity

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2008.242

7 January 2021

Reversibility of acute B-cell leukaemia induced by BCR-ABL1.

1 reference

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7 January 2021

Oncogenic signaling: new insights and controversies from chronic myeloid leukemia

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7 January 2021

A myristoyl/phosphotyrosine switch regulates c-Abl

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2008.242

7 January 2021

A direct binding site for Grb2 contributes to transformation and leukemogenesis by the Tel-Abl (ETV6-Abl) tyrosine kinase

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2008.242

7 January 2021

The development of imatinib as a therapeutic agent for chronic myeloid leukemia

1 reference

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7 January 2021

AMN107 (nilotinib): a novel and selective inhibitor of BCR-ABL

1 reference

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7 January 2021

https://api.crossref.org/works/10.1038%2FLEU.2008.242

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7 January 2021

Fusion of EML1 to ABL1 in T-cell acute lymphoblastic leukemia with cryptic t(9;14)(q34;q32).

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2008.242

7 January 2021

Fusion of NUP214 to ABL1 on amplified episomes in T-cell acute lymphoblastic leukemia

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2008.242

7 January 2021

Kinase activation and transformation by NUP214-ABL1 is dependent on the context of the nuclear pore

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2008.242

7 January 2021

Structural Basis for the Cytoskeletal Association of Bcr-Abl/c-Abl

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2008.242

7 January 2021

A coiled-coil tetramerization domain of BCR-ABL is essential for the interactions of SH2-containing signal transduction molecules

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2008.242

7 January 2021

Activity of tyrosine kinase inhibitors against human NUP214-ABL1-positive T cell malignancies

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2008.242

7 January 2021

Autoinhibition of c-Abl

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2008.242

7 January 2021

Catalytic specificity of protein-tyrosine kinases is critical for selective signalling

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2008.242

7 January 2021

A common phosphotyrosine signature for the Bcr-Abl kinase

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2008.242

7 January 2021

Phosphotyrosine mapping in Bcr/Abl oncoprotein using phosphotyrosine-specific immonium ion scanning

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2008.242

7 January 2021

Profiling of tyrosine phosphorylation pathways in human cells using mass spectrometry

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2008.242

7 January 2021

c-Abl has high intrinsic tyrosine kinase activity that is stimulated by mutation of the Src homology 3 domain and by autophosphorylation at two distinct regulatory tyrosines

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2008.242

7 January 2021

Phosphorylation and structure-based functional studies reveal a positive and a negative role for the activation loop of the c-Abl tyrosine kinase.

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2008.242

7 January 2021

Structural mechanism for STI-571 inhibition of abelson tyrosine kinase

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2008.242

7 January 2021

Structural basis for the autoinhibition of c-Abl tyrosine kinase

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2008.242

7 January 2021

The structure of Dasatinib (BMS-354825) bound to activated ABL kinase domain elucidates its inhibitory activity against imatinib-resistant ABL mutants

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2008.242

7 January 2021

Solution conformations and dynamics of ABL kinase-inhibitor complexes determined by NMR substantiate the different binding modes of imatinib/nilotinib and dasatinib

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2008.242

7 January 2021

The Src tyrosine kinase Hck is required for Tel-Abl- but not for Tel-Jak2-induced cell transformation.

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2008.242

7 January 2021

The Btk tyrosine kinase is a major target of the Bcr-Abl inhibitor dasatinib

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2008.242

7 January 2021

Chemical proteomic profiles of the BCR-ABL inhibitors imatinib, nilotinib, and dasatinib reveal novel kinase and nonkinase targets

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2008.242

7 January 2021

Quantitative chemical proteomics reveals mechanisms of action of clinical ABL kinase inhibitors

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2008.242

7 January 2021

Use of an oriented peptide library to determine the optimal substrates of protein kinases

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2008.242

7 January 2021

Recognition and specificity in protein tyrosine kinase-mediated signalling

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2008.242

7 January 2021

Catalytic domains of tyrosine kinases determine the phosphorylation sites within c-Cbl

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2008.242

7 January 2021

Identifiers

DOI

10.1038/LEU.2008.242

1 reference

21 December 2017

1 reference

21 December 2017