(Q46427537)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15817455%20AND%20SRC:MED&resulttype=core&format=json

10 January 2020

title

The N-acetyl-D-glucosaminylphosphatidylinositol De-N-acetylase of glycosylphosphatidylinositol biosynthesis is a zinc metalloenzyme (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15817455%20AND%20SRC:MED&resulttype=core&format=json

N-acetyl-D-acetylglucosaminylphosphatidylinositol deacetylase

10 January 2020

main subject

1 reference

GeneDB

N-acetyl-D-glucosaminylphosphatidylinositol de-N-acetylase

5 February 2019

1 reference

GeneDB

N-acetyl-D-glucosaminylphosphatidylinositol de-N-acetylase

6 February 2019

0 references

N-Acetyl-D-glucosaminylphosphatidylinositol de-N-acetylase, putative

0 references

N-Acetyl-D-glucosaminylphosphatidylinositol de-N-acetylase, putative

0 references

N-acetyl-D-glucosaminylphosphatidylinositol de-N-acetylase

0 references

N-acetyl-D-glucosaminylphosphatidylinositol de-N-acetylase

0 references

author

Michael D. Urbaniak

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15817455%20AND%20SRC:MED&resulttype=core&format=json

10 January 2020

Michael J. Ferguson

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15817455%20AND%20SRC:MED&resulttype=core&format=json

10 January 2020

Daan van Aalten

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15817455%20AND%20SRC:MED&resulttype=core&format=json

10 January 2020

author name string

Arthur Crossman

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15817455%20AND%20SRC:MED&resulttype=core&format=json

10 January 2020

Tunhan Chang

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15817455%20AND%20SRC:MED&resulttype=core&format=json

10 January 2020

Terry K Smith

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15817455%20AND%20SRC:MED&resulttype=core&format=json

10 January 2020

language of work or name

English

0 references

publication date

6 April 2005

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15817455%20AND%20SRC:MED&resulttype=core&format=json

Journal of Biological Chemistry

10 January 2020

number of pages

8

1 reference

based on heuristic

inferred from page(s)

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15817455%20AND%20SRC:MED&resulttype=core&format=json

10 January 2020

volume

280

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15817455%20AND%20SRC:MED&resulttype=core&format=json

10 January 2020

issue

24

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15817455%20AND%20SRC:MED&resulttype=core&format=json

10 January 2020

page(s)

22831-22838

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15817455%20AND%20SRC:MED&resulttype=core&format=json

The GPI biosynthetic pathway as a therapeutic target for African sleeping sickness.

10 January 2020

cites work

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M502402200

Dissecting and manipulating the pathway for glycosylphos-phatidylinositol-anchor biosynthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M502402200

Inhibitors of glycosyl-phosphatidylinositol anchor biosynthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M502402200

Enzymes and auxiliary factors for GPI lipid anchor biosynthesis and post-translational transfer to proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M502402200

Substrate specificity of the N-acetylglucosaminyl-phosphatidylinositol de-N-acetylase of glycosylphosphatidylinositol membrane anchor biosynthesis in African trypanosomes and human cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M502402200

Antigenic variation in trypanosomes: secrets surface slowly

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M502402200

The glycosylation of the variant surface glycoproteins and procyclic acidic repetitive proteins of Trypanosoma brucei.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M502402200

Cloning of Trypanosoma brucei and Leishmania major genes encoding the GlcNAc-phosphatidylinositol de-N-acetylase of glycosylphosphatidylinositol biosynthesis that is essential to the African sleeping sickness parasite.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M502402200

Essential roles for GPI-anchored proteins in African trypanosomes revealed using mutants deficient in GPI8

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M502402200

Critical roles of glycosylphosphatidylinositol for Trypanosoma brucei

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M502402200

Expression cloning of PIG-L, a candidate N-acetylglucosaminyl-phosphatidylinositol deacetylase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M502402200

Differences between the trypanosomal and human GlcNAc-PI de-N-acetylases of glycosylphosphatidylinositol membrane anchor biosynthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M502402200

Chemical validation of GPI biosynthesis as a drug target against African sleeping sickness

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M502402200

Specificity of GlcNAc-PI de-N-acetylase of GPI biosynthesis and synthesis of parasite-specific suicide substrate inhibitors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M502402200

The crystal structure of 1-D-myo-inosityl 2-acetamido-2-deoxy-alpha-D-glucopyranoside deacetylase (MshB) from Mycobacterium tuberculosis reveals a zinc hydrolase with a lactate dehydrogenase fold

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M502402200

Crystal structure of MshB from Mycobacterium tuberculosis, a deacetylase involved in mycothiol biosynthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M502402200

Further probing of the substrate specificities and inhibition of enzymes involved at an early stage of glycosylphosphatidylinositol (GPI) biosynthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M502402200

Substrate specificity of the dolichol phosphate mannose: glucosaminyl phosphatidylinositol alpha1-4-mannosyltransferase of the glycosylphosphatidylinositol biosynthetic pathway of African trypanosomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M502402200

WHAT IF: a molecular modeling and drug design program

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M502402200

Protein folding and association: insights from the interfacial and thermodynamic properties of hydrocarbons

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M502402200

14 Removal and replacement of metal ions in metallopeptidases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M502402200

Specificities of enzymes of glycosylphosphatidylinositol biosynthesis in Trypanosoma brucei and HeLa cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M502402200

Crystal structure of LpxC, a zinc-dependent deacetylase essential for endotoxin biosynthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M502402200

Targeting metalloenzymes: a strategy that works

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M502402200

T-Coffee: A novel method for fast and accurate multiple sequence alignment

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M502402200

Rapid protein-folding assay using green fluorescent protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M502402200

Parasite-Specific Inhibition of the Glycosylphosphatidylinositol Biosynthetic Pathway by Stereoisomeric Substrate Analogues†

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M502402200