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Apoptosome assembly
scientific article published in January 2008
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instance of
scholarly article
1 reference
stated in
Europe PubMed Central
PubMed publication ID
18662568
retrieved
22 December 2017
reference URL
http://europepmc.org/abstract/MED/18662568
title
Apoptosome assembly
(English)
1 reference
stated in
Europe PubMed Central
PubMed publication ID
18662568
retrieved
22 December 2017
reference URL
http://europepmc.org/abstract/MED/18662568
main subject
apoptosome
1 reference
based on heuristic
inferred from title
author name string
Yigong Shi
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed publication ID
18662568
retrieved
22 December 2017
reference URL
http://europepmc.org/abstract/MED/18662568
language of work or name
English
0 references
publication date
1 January 2008
1 reference
stated in
Europe PubMed Central
PubMed publication ID
18662568
retrieved
22 December 2017
reference URL
http://europepmc.org/abstract/MED/18662568
published in
Methods in Enzymology
1 reference
stated in
Europe PubMed Central
PubMed publication ID
18662568
retrieved
22 December 2017
reference URL
http://europepmc.org/abstract/MED/18662568
volume
442
1 reference
stated in
Europe PubMed Central
PubMed publication ID
18662568
retrieved
22 December 2017
reference URL
http://europepmc.org/abstract/MED/18662568
page(s)
141-156
1 reference
stated in
Europe PubMed Central
PubMed publication ID
18662568
retrieved
22 December 2017
reference URL
http://europepmc.org/abstract/MED/18662568
cites work
Three-dimensional structure of the apoptosome: implications for assembly, procaspase-9 binding, and activation.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2808%2901407-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Calcium blocks formation of apoptosome by preventing nucleotide exchange in Apaf-1
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2808%2901407-9
retrieved
7 January 2021
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inferred from DOI database lookup
Calcium signalling: dynamics, homeostasis and remodelling
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2808%2901407-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mechanisms of caspase activation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2808%2901407-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Biochemical pathways of caspase activation during apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2808%2901407-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Caspase activation involves the formation of the aposome, a large (approximately 700 kDa) caspase-activating complex
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2808%2901407-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Molecular cloning of the interleukin-1 beta converting enzyme
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2808%2901407-9
retrieved
7 January 2021
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inferred from DOI database lookup
Engineering a dimeric caspase-9: a re-evaluation of the induced proximity model for caspase activation
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2808%2901407-9
retrieved
7 January 2021
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inferred from DOI database lookup
Translocation of C. elegans CED-4 to nuclear membranes during programmed cell death
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2808%2901407-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The apical caspase dronc governs programmed and unprogrammed cell death in Drosophila
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2808%2901407-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Interaction of CED-4 with CED-3 and CED-9: a molecular framework for cell death
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2808%2901407-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The C. elegans protein EGL-1 is required for programmed cell death and interacts with the Bcl-2-like protein CED-9
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2808%2901407-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Drosophila caspase DRONC is required for specific developmental cell death pathways and stress-induced apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2808%2901407-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cell death: critical control points
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2808%2901407-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A decade of caspases
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2808%2901407-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Caenorhabditis elegans EGL-1 disrupts the interaction of CED-9 with CED-4 and promotes CED-3 activation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2808%2901407-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Modeling AAA+ ring complexes from monomeric structures.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2808%2901407-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
DRONC, an ecdysone-inducible Drosophila caspase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2808%2901407-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Magnetic fields increase cell survival by inhibiting apoptosis via modulation of Ca2+ influx.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2808%2901407-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The protein structures that shape caspase activity, specificity, activation and inhibition
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2808%2901407-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Nucleotide requirements for the in vitro activation of the apoptosis protein-activating factor-1-mediated caspase pathway
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2808%2901407-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
C. elegans cell survival gene ced-9 encodes a functional homolog of the mammalian proto-oncogene bcl-2.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2808%2901407-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Worms, life, and death (Nobel lecture).
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2808%2901407-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Role of cytochrome c and dATP/ATP hydrolysis in Apaf-1-mediated caspase-9 activation and apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2808%2901407-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
WD-40 repeat region regulates Apaf-1 self-association and procaspase-9 activation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2808%2901407-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Direct physical interaction between the Caenorhabditis elegans 'death proteins' CED-3 and CED-4.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2808%2901407-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
CED-4 induces chromatin condensation in Schizosaccharomyces pombe and is inhibited by direct physical association with CED-9.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2808%2901407-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Distinctive roles of PHAP proteins and prothymosin-alpha in a death regulatory pathway
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2808%2901407-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Control of the cell death pathway by Dapaf-1, a Drosophila Apaf-1/CED-4-related caspase activator
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2808%2901407-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Formation of apoptosome is initiated by cytochrome c-induced dATP hydrolysis and subsequent nucleotide exchange on Apaf-1.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2808%2901407-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Ion channels in cell proliferation and apoptotic cell death
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2808%2901407-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cell volume in the regulation of cell proliferation and apoptotic cell death
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2808%2901407-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Induction of an apoptotic program in cell-free extracts by 2-chloro-2'-deoxyadenosine 5'-triphosphate and cytochrome c
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2808%2901407-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2808%2901407-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Induction of apoptotic program in cell-free extracts: requirement for dATP and cytochrome c
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2808%2901407-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mechanism of Dronc activation in Drosophila cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2808%2901407-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Store depletion and calcium influx
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2808%2901407-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Demonstration of the in vivo interaction of key cell death regulators by structure-based design of second-site suppressors.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2808%2901407-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The apoptosome activates caspase-9 by dimerization
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2808%2901407-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Structural basis of procaspase-9 recruitment by the apoptotic protease-activating factor 1
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2808%2901407-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Pathways of apoptosis in lymphocyte development, homeostasis, and disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2808%2901407-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Dimer formation drives the activation of the cell death protease caspase 9
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2808%2901407-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Structure of the apoptotic protease-activating factor 1 bound to ADP
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2808%2901407-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Molecular mechanisms of caspase regulation during apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2808%2901407-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Dark is a Drosophila homologue of Apaf-1/CED-4 and functions in an evolutionarily conserved death pathway
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2808%2901407-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Caspase-9 and APAF-1 form an active holoenzyme
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2808%2901407-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cytochrome c and dATP-mediated oligomerization of Apaf-1 is a prerequisite for procaspase-9 activation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2808%2901407-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Caspase activation: the induced-proximity model
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2808%2901407-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The role of calcium in the cell cycle: facts and hypotheses
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2808%2901407-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Caenorhabditis elegans CED-4 stimulates CED-3 processing and CED-3-induced apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2808%2901407-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mechanisms of caspase activation and inhibition during apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2808%2901407-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Interaction between the C. elegans cell-death regulators CED-9 and CED-4.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2808%2901407-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Autoactivation of procaspase-9 by Apaf-1-mediated oligomerization
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2808%2901407-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A conserved XIAP-interaction motif in caspase-9 and Smac/DIABLO regulates caspase activity and apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2808%2901407-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Caspase-9 can be activated without proteolytic processing
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2808%2901407-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A novel heterodimeric cysteine protease is required for interleukin-1 beta processing in monocytes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2808%2901407-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Caspases: enemies within
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2808%2901407-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The PIDDosome, a protein complex implicated in activation of caspase-2 in response to genotoxic stress
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2808%2901407-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Interaction and regulation of subcellular localization of CED-4 by CED-9
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2808%2901407-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The Caenorhabditis elegans cell-death protein CED-3 is a cysteine protease with substrate specificities similar to those of the human CPP32 protease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2808%2901407-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Structure of the CED-4-CED-9 complex provides insights into programmed cell death in Caenorhabditis elegans
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2808%2901407-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Structure and activation mechanism of the Drosophila initiator caspase Dronc
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2808%2901407-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
2:1 Stoichiometry of the CED-4-CED-9 complex and the tetrameric CED-4: insights into the regulation of CED-3 activation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2808%2901407-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Prevention of apoptosis by Bcl-2: release of cytochrome c from mitochondria blocked
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2808%2901407-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Essential role of CED-4 oligomerization in CED-3 activation and apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2808%2901407-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Caspase-9 holoenzyme is a specific and optimal procaspase-3 processing machine
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2808%2901407-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A structure of the human apoptosome at 12.8 A resolution provides insights into this cell death platform
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2808%2901407-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Three-dimensional structure of a double apoptosome formed by the Drosophila Apaf-1 related killer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2808%2901407-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The C. elegans cell death gene ced-3 encodes a protein similar to mammalian interleukin-1 beta-converting enzyme
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2808%2901407-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
HAC-1, a Drosophila homolog of APAF-1 and CED-4 functions in developmental and radiation-induced apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2808%2901407-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Apaf-1, a human protein homologous to C. elegans CED-4, participates in cytochrome c-dependent activation of caspase-3
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2808%2901407-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
An APAF-1.cytochrome c multimeric complex is a functional apoptosome that activates procaspase-9
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2808%2901407-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Apoptosome: the cellular engine for the activation of caspase-9.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2808%2901407-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Caspase activation: revisiting the induced proximity model
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2808%2901407-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1016/S0076-6879(08)01407-9
1 reference
stated in
Europe PubMed Central
PubMed publication ID
18662568
retrieved
22 December 2017
reference URL
http://europepmc.org/abstract/MED/18662568
PubMed publication ID
18662568
1 reference
stated in
Europe PubMed Central
PubMed publication ID
18662568
retrieved
22 December 2017
reference URL
http://europepmc.org/abstract/MED/18662568
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