(Q46463850)

22 December 2017

http://europepmc.org/abstract/MED/16237174

title

Fyn kinase induces synaptic and cognitive impairments in a transgenic mouse model of Alzheimer's disease (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6725734&resulttype=core&format=json

12 May 2020

main subject

Alzheimer's disease

0 references

cognitive dysfunction

1 reference

8

Eliezer Masliah

2 references

22 December 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6725734&resulttype=core&format=json

12 May 2020

9

Lennart Mucke

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6725734&resulttype=core&format=json

12 May 2020

author name string

Jeannie Chin

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6725734&resulttype=core&format=json

12 May 2020

Jorge J Palop

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6725734&resulttype=core&format=json

12 May 2020

Jukka Puoliväli

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6725734&resulttype=core&format=json

12 May 2020

Catherine Massaro

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6725734&resulttype=core&format=json

12 May 2020

Nga Bien-Ly

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6725734&resulttype=core&format=json

12 May 2020

Hilary Gerstein

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6725734&resulttype=core&format=json

12 May 2020

Kimberly Scearce-Levie

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6725734&resulttype=core&format=json

12 May 2020

language of work or name

English

0 references

publication date

1 October 2005

1 reference

22 December 2017

http://europepmc.org/abstract/MED/16237174

published in

Journal of Neuroscience

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6725734&resulttype=core&format=json

12 May 2020

volume

25

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6725734&resulttype=core&format=json

12 May 2020

issue

42

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6725734&resulttype=core&format=json

12 May 2020

page(s)

9694-9703

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6725734&resulttype=core&format=json

Plaque-independent disruption of neural circuits in Alzheimer's disease mouse models

12 May 2020

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12 December 2020

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12 December 2020

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Upregulation of surface alpha4beta2 nicotinic receptors is initiated by receptor desensitization after chronic exposure to nicotine

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Higher seizure susceptibility and enhanced tyrosine phosphorylation of N-methyl-D-aspartate receptor subunit 2B in fyn transgenic mice

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12 December 2020

Behavioral changes in transgenic mice expressing both amyloid precursor protein and presenilin-1 mutations: lack of association with amyloid deposits.

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12 December 2020

Environment-specific expression of the immediate-early gene Arc in hippocampal neuronal ensembles.

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12 December 2020

Hypothalamic-pituitary-adrenal dysfunction in Apoe(-/-) mice: possible role in behavioral and metabolic alterations.

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12 December 2020

Inhibition of activity-dependent arc protein expression in the rat hippocampus impairs the maintenance of long-term potentiation and the consolidation of long-term memory.

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12 December 2020

High-level neuronal expression of abeta 1-42 in wild-type human amyloid protein precursor transgenic mice: synaptotoxicity without plaque formation

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12 December 2020

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12 December 2020

Targeting small Abeta oligomers: the solution to an Alzheimer's disease conundrum?

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12 December 2020

Methodological and conceptual issues in the use of the elevated plus-maze as a psychological measurement instrument of animal anxiety-like behavior

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12 December 2020

Spatial Memory and Learning in Transgenic Mice: Fact or Artifact?

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12 December 2020

Beta-amyloid activates the mitogen-activated protein kinase cascade via hippocampal alpha7 nicotinic acetylcholine receptors: In vitro and in vivo mechanisms related to Alzheimer's disease

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12 December 2020

Upregulation of the immediate early gene arc in the brains of rats exposed to environmental enrichment: implications for molecular plasticity

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12 December 2020

Arg3.1/Arc mRNA induction by Ca2+ and cAMP requires protein kinase A and mitogen-activated protein kinase/extracellular regulated kinase activation.

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12 December 2020

Rapid tyrosine phosphorylation of neuronal proteins including tau and focal adhesion kinase in response to amyloid-beta peptide exposure: involvement of Src family protein kinases.

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A role of Fos expression in the CA3 region of the hippocampus in spatial memory formation in rats.

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12 December 2020

Insulin-induced expression of the activity-regulated cytoskeleton-associated gene (ARC) in human neuroblastoma cells requires p21(ras), mitogen-activated protein kinase/extracellular regulated kinase and src tyrosine kinases but is protein kinase C-

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12 December 2020

Brain-derived neurotrophic factor induces long-term potentiation in intact adult hippocampus: requirement for ERK activation coupled to CREB and upregulation of Arc synthesis.

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12 December 2020

The relationship between Abeta and memory in the Tg2576 mouse model of Alzheimer's disease.

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12 December 2020

Insights into immediate-early gene function in hippocampal memory consolidation using antisense oligonucleotide and fluorescent imaging approaches

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12 December 2020

Tyrosine phosphatase STEP is a tonic brake on induction of long-term potentiation

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12 December 2020

Striatal enriched phosphatase 61 dephosphorylates Fyn at phosphotyrosine 420.

1 reference

12 December 2020

Uptake and pathogenic effects of amyloid beta peptide 1-42 are enhanced by integrin antagonists and blocked by NMDA receptor antagonists

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12 December 2020

Characterization of neuronal dystrophy induced by fibrillar amyloid beta: implications for Alzheimer's disease

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12 December 2020

Epidemiology of neurodegeneration

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12 December 2020

Neuronal depletion of calcium-dependent proteins in the dentate gyrus is tightly linked to Alzheimer's disease-related cognitive deficits

1 reference

12 December 2020

Roles of amyloid precursor protein and its fragments in regulating neural activity, plasticity and memory

1 reference

12 December 2020

Transgenic mouse models of Alzheimer's disease: phenotype and application

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12 December 2020

Binding sites of amyloid beta-peptide in cell plasma membrane and implications for Alzheimer's disease

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12 December 2020

Src kinases: a hub for NMDA receptor regulation

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12 December 2020

Transgenic animal models of Alzheimer's disease and related disorders: histopathology, behavior and therapy.

1 reference

12 December 2020

Progressive cognitive impairment and anxiety induction in the absence of plaque deposition in C57BL/6 inbred mice expressing transgenic amyloid precursor protein

1 reference

12 December 2020

Fyn kinase modulates synaptotoxicity, but not aberrant sprouting, in human amyloid precursor protein transgenic mice.

1 reference

12 December 2020

Mitogen-activated protein kinases in synaptic plasticity and memory.

1 reference

12 December 2020

Molecular genetics of late-onset Alzheimer's disease.

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12 December 2020

Translational regulatory mechanisms in persistent forms of synaptic plasticity

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12 December 2020

Deciphering the molecular basis of memory failure in Alzheimer's disease

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12 December 2020

RAGE potentiates Abeta-induced perturbation of neuronal function in transgenic mice

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12 December 2020

Src protein-tyrosine kinase structure and regulation

1 reference

12 December 2020

Twenty years of the Alzheimer's disease amyloid hypothesis: a genetic perspective

1 reference

12 December 2020

Behavioral phenotypes of amyloid-based genetically modified mouse models of Alzheimer's disease

1 reference

12 December 2020

Prion protein recruits its neuronal receptor NCAM to lipid rafts to activate p59fyn and to enhance neurite outgrowth.

1 reference

12 December 2020

Sparse, environmentally selective expression of Arc RNA in the upper blade of the rodent fascia dentata by brief spatial experience

1 reference

12 December 2020

Regulation of NMDA receptor trafficking by amyloid-beta

1 reference

12 December 2020

Vulnerability of dentate granule cells to disruption of arc expression in human amyloid precursor protein transgenic mice.

1 reference

12 December 2020

Physical basis of cognitive alterations in alzheimer's disease: Synapse loss is the major correlate of cognitive impairment

1 reference

12 December 2020

Levels and alternative splicing of amyloid beta protein precursor (APP) transcripts in brains of APP transgenic mice and humans with Alzheimer's disease

1 reference

12 December 2020

Protection against HIV-1 gp120-induced brain damage by neuronal expression of human amyloid precursor protein

1 reference

12 December 2020

Interaction of beta-amyloid peptides with integrins in a human nerve cell line

1 reference

12 December 2020

Use of the elevated plus maze in the search for novel anxiolytic agents

1 reference

12 December 2020

Arc, a growth factor and activity-regulated gene, encodes a novel cytoskeleton-associated protein that is enriched in neuronal dendrites

1 reference

12 December 2020

Central nervous system damage produced by expression of the HIV-1 coat protein gp120 in transgenic mice.

1 reference

12 December 2020

The protein tyrosine kinase, fyn, in Alzheimer's disease pathology

1 reference

12 December 2020

Molecular profile of reactive astrocytes--implications for their role in neurologic disease

1 reference

12 December 2020

RAGE and amyloid-beta peptide neurotoxicity in Alzheimer's disease

1 reference

12 December 2020

Deficits in memory and hippocampal long-term potentiation in mice with reduced calbindin D28K expression.

1 reference

12 December 2020

Neuropsychiatric aspects of Alzheimer's disease: the cholinergic hypothesis revisited

1 reference

12 December 2020

Rescuing impairment of long-term potentiation in fyn-deficient mice by introducing Fyn transgene

1 reference

12 December 2020

The postsynaptic density at glutamatergic synapses

1 reference

12 December 2020

Binding of beta-amyloid to the p75 neurotrophin receptor induces apoptosis. A possible mechanism for Alzheimer's disease.

1 reference

12 December 2020

Cellular functions regulated by Src family kinases

1 reference

12 December 2020

Diffusible, nonfibrillar ligands derived from Abeta1-42 are potent central nervous system neurotoxins

1 reference

12 December 2020

Genetically modified mice and cognition

1 reference

12 December 2020

Synaptic activation causes the mRNA for the IEG Arc to localize selectively near activated postsynaptic sites on dendrites

1 reference

12 December 2020

10.1523/JNEUROSCI.2980-05.2005

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6725734&resulttype=core&format=json

12 May 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6725734&resulttype=core&format=json

12 May 2020

1 reference