(Q46520637)

English

CD44-epidermal growth factor receptor interaction mediates hyaluronic acid-promoted cell motility by activating protein kinase C signaling involving Akt, Rac1, Phox, reactive oxygen species, focal adhesion kinase, and MMP-2.

scientific article published on 24 June 2008

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scholarly article

1 reference

Europe PubMed Central

22 December 2017

http://europepmc.org/abstract/MED/18577517

CD44-epidermal growth factor receptor interaction mediates hyaluronic acid-promoted cell motility by activating protein kinase C signaling involving Akt, Rac1, Phox, reactive oxygen species, focal adhesion kinase, and MMP-2. (English)

1 reference

Europe PubMed Central

22 December 2017

http://europepmc.org/abstract/MED/18577517

reactive oxygen species

1 reference

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author name string

Youngmi Kim

1

1 reference

Europe PubMed Central

22 December 2017

http://europepmc.org/abstract/MED/18577517

Yun-Sil Lee

2

1 reference

Europe PubMed Central

22 December 2017

http://europepmc.org/abstract/MED/18577517

Jongseon Choe

3

1 reference

Europe PubMed Central

22 December 2017

http://europepmc.org/abstract/MED/18577517

Hansoo Lee

4

1 reference

Europe PubMed Central

22 December 2017

http://europepmc.org/abstract/MED/18577517

Young-Myeong Kim

5

1 reference

Europe PubMed Central

22 December 2017

http://europepmc.org/abstract/MED/18577517

Dooil Jeoung

6

1 reference

Europe PubMed Central

22 December 2017

http://europepmc.org/abstract/MED/18577517

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publication date

24 June 2008

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Europe PubMed Central

22 December 2017

http://europepmc.org/abstract/MED/18577517

number of pages

16

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Journal of Biological Chemistry

1 reference

Europe PubMed Central

22 December 2017

http://europepmc.org/abstract/MED/18577517

283

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Europe PubMed Central

22 December 2017

http://europepmc.org/abstract/MED/18577517

33

1 reference

Europe PubMed Central

22 December 2017

http://europepmc.org/abstract/MED/18577517

22513-22528

1 reference

Europe PubMed Central

22 December 2017

http://europepmc.org/abstract/MED/18577517

Antisense-mediated suppression of hyaluronan synthase 2 inhibits the tumorigenesis and progression of breast cancer.

1 reference

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Sodium hyaluronate (hyaluronic acid) promotes migration of human corneal epithelial cells in vitro.

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Hyaluronan inhibits osteoclast differentiation via Toll-like receptor 4.

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Hyaluronan facilitates invasion of colon carcinoma cells in vitro via interaction with CD44.

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Osteopontin induction of hyaluronan synthase 2 expression promotes breast cancer malignancy

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RHAMM, a receptor for hyaluronan-mediated motility, compensates for CD44 in inflamed CD44-knockout mice: a different interpretation of redundancy

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The hyaluronan receptors CD44 and Rhamm (CD168) form complexes with ERK1,2 that sustain high basal motility in breast cancer cells

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Inhibition of cell migration, spreading, and focal adhesions by tumor suppressor PTEN

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1 reference

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1 reference

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1 reference

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21 January 2018

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1 reference

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21 January 2018

Fer-mediated cortactin phosphorylation is associated with efficient fibroblast migration and is dependent on reactive oxygen species generation during integrin-mediated cell adhesion

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21 January 2018

Reactive oxygen species in vascular endothelial cell motility. Roles of NAD(P)H oxidase and Rac1.

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21 January 2018

Nox1-dependent reactive oxygen generation is regulated by Rac1

1 reference

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21 January 2018

Phosphatidylinositol 3-kinase gamma signaling through protein kinase Czeta induces NADPH oxidase-mediated oxidant generation and NF-kappaB activation in endothelial cells

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21 January 2018

A decrease in the molecular weight of hyaluronic acid in synovial fluid from patients with temporomandibular disorders

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21 January 2018

Twist transcriptionally up-regulates AKT2 in breast cancer cells leading to increased migration, invasion, and resistance to paclitaxel

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Angiopoietin 2 induces glioma cell invasion by stimulating matrix metalloprotease 2 expression through the alphavbeta1 integrin and focal adhesion kinase signaling pathway

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21 January 2018

Matrix metalloproteinase 2 (MMP2) and MMP9 secreted by erythropoietin-activated endothelial cells promote neural progenitor cell migration.

1 reference

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21 January 2018

Hypoxia stimulates breast carcinoma cell invasion through MT1-MMP and MMP-2 activation

1 reference

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21 January 2018

Ethanol-induced in vitro invasion of breast cancer cells: the contribution of MMP-2 by fibroblasts

1 reference

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21 January 2018

Hyaluronan constitutively regulates activation of multiple receptor tyrosine kinases in epithelial and carcinoma cells

1 reference

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21 January 2018

Liposomes comprising anionic but not neutral phospholipids cause dissociation of Rac(1 or 2) x RhoGDI complexes and support amphiphile-independent NADPH oxidase activation by such complexes

1 reference

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21 January 2018

Phosphorylation of RhoGDI by Src regulates Rho GTPase binding and cytosol-membrane cycling

1 reference

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21 January 2018

PKC mediates cyclic stretch-induced cardiac hypertrophy through Rho family GTPases and mitogen-activated protein kinases in cardiomyocytes

1 reference

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PKCdelta mediates up-regulation of NOX1, a catalytic subunit of NADPH oxidase, via transactivation of the EGF receptor: possible involvement of PKCdelta in vascular hypertrophy

1 reference

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The Wnt5A/protein kinase C pathway mediates motility in melanoma cells via the inhibition of metastasis suppressors and initiation of an epithelial to mesenchymal transition.

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Rac1b and reactive oxygen species mediate MMP-3-induced EMT and genomic instability

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Association of focal adhesion kinase with Grb7 and its role in cell migration

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IQGAP1 regulates reactive oxygen species-dependent endothelial cell migration through interacting with Nox2.

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Identifiers

10.1074/JBC.M708319200

1 reference

Europe PubMed Central

22 December 2017

http://europepmc.org/abstract/MED/18577517

1 reference

Europe PubMed Central

22 December 2017

http://europepmc.org/abstract/MED/18577517

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