(Q46548978)

English

Lupeol, a fruit and vegetable based triterpene, induces apoptotic death of human pancreatic adenocarcinoma cells via inhibition of Ras signaling pathway.

scientific article published on 15 June 2005

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scholarly article

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15958516%20AND%20SRC:MED&resulttype=core&format=json

12 January 2020

Lupeol, a fruit and vegetable based triterpene, induces apoptotic death of human pancreatic adenocarcinoma cells via inhibition of Ras signaling pathway (English)

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15958516%20AND%20SRC:MED&resulttype=core&format=json

12 January 2020

1 reference

based on heuristic

inferred from title

pancreatic adenocarcinoma

1 reference

based on heuristic

inferred from title

apoptotic process

1 reference

based on heuristic

inferred from title

Mohammad Saleem

1

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15958516%20AND%20SRC:MED&resulttype=core&format=json

12 January 2020

Satwinderjeet Kaur

2

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15958516%20AND%20SRC:MED&resulttype=core&format=json

12 January 2020

author name string

Mee-Hyang Kweon

3

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15958516%20AND%20SRC:MED&resulttype=core&format=json

12 January 2020

Vaqar Mustafa Adhami

4

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15958516%20AND%20SRC:MED&resulttype=core&format=json

12 January 2020

Farrukh Afaq

5

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15958516%20AND%20SRC:MED&resulttype=core&format=json

12 January 2020

Hasan Mukhtar

6

1 reference

Europe PubMed Central

PubMed publication ID

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12 January 2020

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publication date

15 June 2005

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15958516%20AND%20SRC:MED&resulttype=core&format=json

12 January 2020

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15958516%20AND%20SRC:MED&resulttype=core&format=json

12 January 2020

26

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12 January 2020

11

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12 January 2020

1956-1964

1 reference

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PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15958516%20AND%20SRC:MED&resulttype=core&format=json

12 January 2020

Cancer statistics, 2005

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGI157

21 January 2018

Most human carcinomas of the exocrine pancreas contain mutant c-K-ras genes

1 reference

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21 January 2018

Pancreatic tumor cells with mutant K-ras suppress ERK activity by MEK-dependent induction of MAP kinase phosphatase-2.

1 reference

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Molecular targeting therapy for pancreatic cancer

1 reference

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The PI 3-kinase/Akt signaling pathway is activated due to aberrant Pten expression and targets transcription factors NF-kappaB and c-Myc in pancreatic cancer cells

1 reference

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Dominant negative inhibitors of signalling through the phosphoinositol 3-kinase pathway for gene therapy of pancreatic cancer

1 reference

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21 January 2018

Diet and pancreatic cancer: a case-control study

1 reference

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21 January 2018

Lifetime consumption of alcoholic beverages, tea and coffee and exocrine carcinoma of the pancreas: a population-based case-control study in The Netherlands

1 reference

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21 January 2018

Lupeol, a triterpene, inhibits early responses of tumor promotion induced by benzoyl peroxide in murine skin

1 reference

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21 January 2018

Phytosterol content in American ginseng seed oil.

1 reference

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21 January 2018

Triterpenoids from Gentiana scabra

1 reference

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21 January 2018

Antiprotease effect of anti-inflammatory lupeol esters

1 reference

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21 January 2018

Screening of triterpenoids isolated from Phyllanthus flexuosus for DNA topoisomerase inhibitory activity

1 reference

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21 January 2018

Role of p38 MAPK in Lupeol-Induced B16 2F2 Mouse Melanoma Cell Differentiation

1 reference

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21 January 2018

Anti-leukemia activities of Lup-28-al-20(29)-en-3-one, a lupane triterpene

1 reference

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21 January 2018

Lupeol modulates NF-kappaB and PI3K/Akt pathways and inhibits skin cancer in CD-1 mice.

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGI157

21 January 2018

Modulation of poly(ADP-ribosylation) in apoptotic cells

1 reference

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21 January 2018

Ablation of either p21 or Bax prevents p53-dependent apoptosis induced by green tea polyphenol epigallocatechin-3-gallate.

1 reference

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21 January 2018

Involvement of nuclear factor-kappa B, Bax and Bcl-2 in induction of cell cycle arrest and apoptosis by apigenin in human prostate carcinoma cells

1 reference

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21 January 2018

Caspases: potential targets for regulating cell death.

1 reference

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21 January 2018

Molecular mechanisms of caspase regulation during apoptosis

1 reference

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21 January 2018

RAS inhibitors in hematologic cancers: biologic considerations and clinical applications

1 reference

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21 January 2018

Targeting protein kinase C: new therapeutic opportunities against high-grade malignant gliomas?

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21 January 2018

Nonmutagenic mechanisms in carcinogenesis: role of protein kinase C in signal transduction and growth control

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21 January 2018

Prognostic significance of activated Akt expression in pancreatic ductal adenocarcinoma

1 reference

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21 January 2018

Targeting the mitogen-activated protein kinase cascade to treat cancer

1 reference

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21 January 2018

Nuclear factor-kappaB: its role in health and disease

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21 January 2018

Apoptosis-inducing effect of chemotherapeutic agents is potentiated by soy isoflavone genistein, a natural inhibitor of NF-kappaB in BxPC-3 pancreatic cancer cell line

1 reference

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21 January 2018

Death and anti-death: tumour resistance to apoptosis

1 reference

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21 January 2018

Inhibition of integrin-linked kinase by a selective small molecule inhibitor, QLT0254, inhibits the PI3K/PKB/mTOR, Stat3, and FKHR pathways and tumor growth, and enhances gemcitabine-induced apoptosis in human orthotopic primary pancreatic cancer xe

1 reference

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21 January 2018

Involvement of p38 mitogen-activated protein kinase in gemcitabine-induced apoptosis in human pancreatic cancer cells

1 reference

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21 January 2018

MEK/ERK-mediated proliferation is negatively regulated by P38 map kinase in the human pancreatic cancer cell line, PANC-1.

1 reference

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21 January 2018

H-Ras-specific activation of Rac-MKK3/6-p38 pathway: its critical role in invasion and migration of breast epithelial cells

1 reference

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21 January 2018

Nuclear factor-kappaB and IkappaB kinase are constitutively active in human pancreatic cells, and their down-regulation by curcumin (diferuloylmethane) is associated with the suppression of proliferation and the induction of apoptosis

1 reference

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21 January 2018

Signal transduction pathways linking polyamines to apoptosis.

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21 January 2018

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