(Q46557452)

English

Melatonin enhances mitochondrial ATP synthesis, reduces reactive oxygen species formation, and mediates translocation of the nuclear erythroid 2-related factor 2 resulting in activation of phase-2 antioxidant enzymes (γ-GCS, HO-1, NQO1) in ultraviol

scientific article published on 27 April 2016

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scholarly article

1 reference

Europe PubMed Central

23 December 2017

http://europepmc.org/abstract/MED/27117941

Melatonin enhances mitochondrial ATP synthesis, reduces reactive oxygen species formation, and mediates translocation of the nuclear erythroid 2-related factor 2 resulting in activation of phase-2 antioxidant enzymes (γ-GCS, HO-1, NQO1) in ultraviol (English)

1 reference

Europe PubMed Central

23 December 2017

http://europepmc.org/abstract/MED/27117941

0 references

reactive oxygen species

1 reference

based on heuristic

inferred from title

Detlef Zillikens

2

object named as

Detlef Zillikens

1 reference

Europe PubMed Central

23 December 2017

Konrad Kleszczyński

1

object named as

Konrad Kleszczyński

1 reference

Europe PubMed Central

23 December 2017

http://europepmc.org/abstract/MED/27117941

author name string

Tobias W Fischer

3

1 reference

Europe PubMed Central

23 December 2017

http://europepmc.org/abstract/MED/27117941

publication date

27 April 2016

1 reference

Europe PubMed Central

23 December 2017

http://europepmc.org/abstract/MED/27117941

Journal of Pineal Research

1 reference

Europe PubMed Central

23 December 2017

http://europepmc.org/abstract/MED/27117941

61

1 reference

Europe PubMed Central

23 December 2017

http://europepmc.org/abstract/MED/27117941

2

1 reference

Europe PubMed Central

23 December 2017

http://europepmc.org/abstract/MED/27117941

187-197

1 reference

Europe PubMed Central

23 December 2017

http://europepmc.org/abstract/MED/27117941

Toxic effects of ultraviolet radiation on the skin

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Animals under the sun: effects of ultraviolet radiation on mammalian skin.

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Cytochromes p450 and skin cancer: role of local endocrine pathways

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Direct monitoring of UV-induced free radical generation in HaCaT keratinocytes

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UVB light stimulates production of reactive oxygen species: unexpected role for catalase

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Investigating the role of melanin in UVA/UVB- and hydrogen peroxide-induced cellular and mitochondrial ROS production and mitochondrial DNA damage in human melanoma cells

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DNA damage, death receptor activation and reactive oxygen species contribute to ultraviolet radiation-induced apoptosis in an essential and independent way.

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Cyclobutane pyrimidine dimers are predominant DNA lesions in whole human skin exposed to UVA radiation.

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UV wavelength-dependent DNA damage and human non-melanoma and melanoma skin cancer

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The antioxidative potential of melatonin in the skin

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Protective effects of melatonin in reducing oxidative stress and in preserving the fluidity of biological membranes: a review

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Melatonin as a major skin protectant: from free radical scavenging to DNA damage repair

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Cellular localization and kinetics of the rice melatonin biosynthetic enzymes SNAT and ASMT.

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Melatonin: the smart killer: the human trophoblast as a model

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Phytomelatonin: assisting plants to survive and thrive

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Pineal Melatonin: Cell Biology of Its Synthesis and of Its Physiological Interactions*

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Natural melatonin 'knockdown' in C57BL/6J mice: rare mechanism truncates serotonin N-acetyltransferase.

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A survey of molecular details in the human pineal gland in the light of phylogeny, structure, function and chronobiological diseases

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Characterization of the serotoninergic system in the C57BL/6 mouse skin.

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High physiological levels of melatonin in the bile of mammals

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Constitutive and UV-induced metabolism of melatonin in keratinocytes and cell-free systems

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21 January 2018

On the role of melatonin in skin physiology and pathology.

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The role of melatonin in the cells of the innate immunity: a review

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Melatonin and its metabolites accumulate in the human epidermis in vivo and inhibit proliferation and tyrosinase activity in epidermal melanocytes in vitro.

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21 January 2018

Melatonin enhances antioxidative enzyme gene expression (CAT, GPx, SOD), prevents their UVR-induced depletion, and protects against the formation of DNA damage (8-hydroxy-2'-deoxyguanosine) in ex vivo human skin.

1 reference

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21 January 2018

Melatonin suppresses reactive oxygen species induced by UV irradiation in leukocytes

1 reference

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21 January 2018

Local melatoninergic system as the protector of skin integrity

1 reference

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21 January 2018

Functional activity of serotoninergic and melatoninergic systems expressed in the skin

1 reference

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21 January 2018

Melatonin membrane receptors in peripheral tissues: distribution and functions

1 reference

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21 January 2018

Extrapineal melatonin: analysis of its subcellular distribution and daily fluctuations

1 reference

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21 January 2018

Melatonin increases survival of HaCaT keratinocytes by suppressing UV-induced apoptosis

1 reference

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21 January 2018

Melatonin downregulates nuclear erythroid 2-related factor 2 and nuclear factor-kappaB during prevention of oxidative liver injury in a dimethylnitrosamine model.

1 reference

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21 January 2018

Melatonin induces the expression of Nrf2-regulated antioxidant enzymes via PKC and Ca2+ influx activation in mouse pancreatic acinar cells.

1 reference

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21 January 2018

Melatonin activates the Nrf2-ARE pathway when it protects against early brain injury in a subarachnoid hemorrhage model.

1 reference

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21 January 2018

Mitochondrial DNA as a biosensor of UV exposure in human skin.

1 reference

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21 January 2018

Low doses of ultraviolet radiation and oxidative damage induce dramatic accumulation of mitochondrial DNA replication intermediates, fork regression, and replication initiation shift

1 reference

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21 January 2018

Mitochondria in health and disease: perspectives on a new mitochondrial biology

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Altered Mitochondrial DNA Methylation Pattern in Alzheimer Disease-Related Pathology and in Parkinson Disease.

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A Unifying Mechanism for Mitochondrial Superoxide Production during Ischemia-Reperfusion Injury

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Sex difference in the sensitivity of cardiac mitochondrial permeability transition pore to calcium load.

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Mitochondrial dysfunction and longevity in animals: Untangling the knot

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Induction of the photoaging-associated mitochondrial common deletion in vivo in normal human skin

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Stressed out mitochondria: the role of mitochondria in ageing and cancer focussing on strategies and opportunities in human skin

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Melatonin maintains mitochondrial membrane potential and attenuates activation of initiator (casp-9) and effector caspases (casp-3/casp-7) and PARP in UVR-exposed HaCaT keratinocytes

1 reference

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21 January 2018

Mitochondrial function evaluation in epidermal cells ex vivo after ultraviolet irradiation

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21 January 2018

Determination of the Action Spectrum of UVR-Induced Mitochondrial DNA Damage in Human Skin Cells.

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Visualization of the antioxidative effects of melatonin at the mitochondrial level during oxidative stress-induced apoptosis of rat brain astrocytes

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21 January 2018

Melatonin mitigates mitochondrial malfunction

1 reference

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21 January 2018

Protective role of melatonin in mitochondrial dysfunction and related disorders

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21 January 2018

Melatonin reduces UV-induced reactive oxygen species in a dose-dependent manner in IL-3-stimulated leukocytes

1 reference

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21 January 2018

Melatonin: a well-documented antioxidant with conditional pro-oxidant actions

1 reference

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21 January 2018

Melatonin suppresses reactive oxygen species in UV-irradiated leukocytes more than vitamin C and trolox

1 reference

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21 January 2018

The Keap1-Nrf2-antioxidant response element pathway: a review of its regulation by melatonin and the proteasome.

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21 January 2018

Cell survival responses to environmental stresses via the Keap1-Nrf2-ARE pathway

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21 January 2018

Sulforaphane and phenylethyl isothiocyanate protect human skin against UVR-induced oxidative stress and apoptosis: role of Nrf2-dependent gene expression and antioxidant enzymes

1 reference

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21 January 2018

Melatonin: an ancient molecule that makes oxygen metabolically tolerable.

1 reference

https://api.crossref.org/works/10.1111%2FJPI.12338

21 January 2018

Melatonin prevents ultraviolet radiation-induced alterations in plasma membrane potential and intracellular pH in human keratinocytes.

1 reference

https://api.crossref.org/works/10.1111%2FJPI.12338

21 January 2018

Chronic melatonin treatment reduces the age-dependent inflammatory process in senescence-accelerated mice.

1 reference

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21 January 2018

One molecule, many derivatives: a never-ending interaction of melatonin with reactive oxygen and nitrogen species?

1 reference

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Melatonin compensates silencing of heat shock protein 70 and suppresses ultraviolet radiation-induced inflammation in human skin ex vivo and cultured keratinocytes

1 reference

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21 January 2018

Identifiers

10.1111/JPI.12338

1 reference

Europe PubMed Central

23 December 2017

http://europepmc.org/abstract/MED/27117941

1 reference

Europe PubMed Central

23 December 2017

http://europepmc.org/abstract/MED/27117941

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