(Q46567817)

23 December 2017

title

Microglial cells and Parkinson's disease (English)

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23 December 2017

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1

Qian L

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23 December 2017

P.M. Flood

series ordinal

2

object named as

Flood PM

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23 December 2017

language of work or name

English

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publication date

1 January 2008

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23 December 2017

published in

Immunologic Research

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23 December 2017

volume

41

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23 December 2017

issue

3

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23 December 2017

page(s)

155-164

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23 December 2017

https://scigraph.springernature.com/pub.10.1007/s12026-008-8018-0

exact match

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cites work

Reactive microglia are positive for HLA-DR in the substantia nigra of Parkinson's and Alzheimer's disease brains

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Minocycline provides neuroprotection against N-methyl-D-aspartate neurotoxicity by inhibiting microglia

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Human microglia convert l-tryptophan into the neurotoxin quinolinic acid

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TGF-beta 1 protects hippocampal neurons against degeneration caused by transient global ischemia. Dose-response relationship and potential neuroprotective mechanisms.

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Microglia-mediated neurotoxicity is inhibited by morphine through an opioid receptor-independent reduction of NADPH oxidase activity.

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Beta-amyloid-stimulated microglia induce neuron death via synergistic stimulation of tumor necrosis factor alpha and NMDA receptors.

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In utero bacterial endotoxin exposure causes loss of tyrosine hydroxylase neurons in the postnatal rat midbrain.

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TGF-betas and their roles in the regulation of neuron survival

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Neuroinflammation, Oxidative Stress and the Pathogenesis of Parkinson's Disease

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Amelioration of rat experimental arthritides by treatment with the alkaloid sinomenine

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Microglial secreted cathepsin B induces neuronal apoptosis.

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Regional difference in susceptibility to lipopolysaccharide-induced neurotoxicity in the rat brain: role of microglia

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Epicutaneously induced TGF-beta-dependent tolerance inhibits experimental autoimmune encephalomyelitis.

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12 December 2020

Impairment of macrophage eicosanoid and nitric oxide production by an alkaloid from Sinomenium acutum.

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Reduction of endogenous transforming growth factors beta prevents ontogenetic neuron death

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12 December 2020

Neuroprotective activities of CD4+CD25+ regulatory T cells in an animal model of Parkinson's disease

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Involvement of the cystine transport system xc- in the macrophage-induced glutamate-dependent cytotoxicity to neurons

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Activation and assembly of the NADPH oxidase: a structural perspective

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Transforming growth factor beta1 prevents IL-1beta-induced microglial activation, whereas TNFalpha- and IL-6-stimulated activation are not antagonized

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12 December 2020

Postencephalitic parkinsonism--a review

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Role of microglia in inflammation-mediated neurodegenerative diseases: mechanisms and strategies for therapeutic intervention.

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Microglia in diseases of the central nervous system

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Activated microglia mediate neuronal cell injury via a nitric oxide mechanism

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Production of superoxide anions by a CNS macrophage, the microglia

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Trauma as an etiology of parkinsonism: a historical review of the concept

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Nitric oxide synthase and neuronal vulnerability in Parkinson's disease.

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Up-regulation of a serine protease inhibitor in astrocytes mediates the neuroprotective activity of transforming growth factor beta1.

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Microglial reaction in MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine) induced Parkinson's disease mice model

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12 December 2020

Methamphetamine- and 1-methyl-4-phenyl- 1,2,3, 6-tetrahydropyridine-induced dopaminergic neurotoxicity in inducible nitric oxide synthase-deficient mice

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Microglia enhance beta-amyloid peptide-induced toxicity in cortical and mesencephalic neurons by producing reactive oxygen species.

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Synergistic effects of the alkaloid sinomenine in combination with the immunosuppressive drugs tacrolimus and mycophenolic acid

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Ion channel blockade attenuates aggregated alpha synuclein induction of microglial reactive oxygen species: relevance for the pathogenesis of Parkinson's disease.

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Neuroinflammation in the pathophysiology of Parkinson's disease: evidence from animal models to human in vivo studies with [11C]-PK11195 PET

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Transforming growth factor-beta 1 produced by hippocampal cells modulates microglial reactivity in culture.

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Dextromethorphan protects dopaminergic neurons against inflammation-mediated degeneration through inhibition of microglial activation.

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Study progress in Sinomenium acutum (Thunb.) Rehd. et Wils

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NADPH oxidase mediates lipopolysaccharide-induced neurotoxicity and proinflammatory gene expression in activated microglia.

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Role of microglia in inflammation-mediated degeneration of dopaminergic neurons: neuroprotective effect of interleukin 10

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A Transforming Growth Factor-β Antagonist Unmasks the Neuroprotective Role of This Endogenous Cytokine in Excitotoxic and Ischemic Brain Injury

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TGF-beta modulates programmed cell death in the retina of the developing chick embryo

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12 December 2020

Selective inhibition of NF-kappaB activation prevents dopaminergic neuronal loss in a mouse model of Parkinson's disease

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12 December 2020

Deficiency of inducible nitric oxide synthase protects against MPTP toxicity in vivo

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12 December 2020

Increased toxicity by transforming growth factor-beta 1 in liver cells overexpressing CYP2E1

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12 December 2020

Changes in cytokines and neurotrophins in Parkinson's disease

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12 December 2020

Increased cerebrospinal fluid concentration of nitrite in Parkinson's disease

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12 December 2020

Inducible nitric oxide synthase stimulates dopaminergic neurodegeneration in the MPTP model of Parkinson disease

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12 December 2020

Blockade of microglial activation is neuroprotective in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson disease.

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12 December 2020

Microglia as a pharmacological target in infectious and inflammatory diseases of the brain

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12 December 2020

Induction of serine racemase expression and D-serine release from microglia by amyloid beta-peptide

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12 December 2020

NADPH oxidase inhibitor DPI is neuroprotective at femtomolar concentrations through inhibition of microglia over-activation.

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12 December 2020

Lipopolysaccharide-mediated reactive oxygen species and signal transduction in the regulation of interleukin-1 gene expression

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12 December 2020

Naloxone protects rat dopaminergic neurons against inflammatory damage through inhibition of microglia activation and superoxide generation.

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12 December 2020

Murine brain macrophages induced NMDA receptor mediated neurotoxicity in vitro by secreting glutamate

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12 December 2020

Aggregated alpha-synuclein activates microglia: a process leading to disease progression in Parkinson's disease

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12 December 2020

Stimulation of microglial metabotropic glutamate receptor mGlu2 triggers tumor necrosis factor alpha-induced neurotoxicity in concert with microglial-derived Fas ligand.

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12 December 2020

EGF blocks NADPH oxidase activation by TGF-beta in fetal rat hepatocytes, impairing oxidative stress, and cell death.

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12 December 2020

Regulation of neuronal Bcl2 protein expression and calcium homeostasis by transforming growth factor type beta confers wide-ranging protection on rat hippocampal neurons

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12 December 2020

MPTP and SNpc DA neuronal vulnerability: role of dopamine, superoxide and nitric oxide in neurotoxicity. Minireview

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12 December 2020

Minocycline prevents nigrostriatal dopaminergic neurodegeneration in the MPTP model of Parkinson's disease

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12 December 2020

Interleukin-1 beta, interleukin-6, epidermal growth factor and transforming growth factor-alpha are elevated in the brain from parkinsonian patients

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12 December 2020

Systemic infusion of naloxone reduces degeneration of rat substantia nigral dopaminergic neurons induced by intranigral injection of lipopolysaccharide

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12 December 2020

Effects of enhanced striatal dopamine turnover in vivo on glutathione oxidation

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12 December 2020

Role of nitric oxide in inflammation-mediated neurodegeneration.

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12 December 2020

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12 December 2020

The pharmacology of sinomenine. VII. Effect of sinomenine on the gastro-intestinal movement and its mechanism

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12 December 2020

Protection by sinomenine against endotoxin-induced fulminant hepatitis in galactosamine-sensitized mice

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12 December 2020

Transforming growth factor-beta 1 increases bad phosphorylation and protects neurons against damage.

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12 December 2020

Lipopolysaccharide induces Rac1-dependent reactive oxygen species formation and coordinates tumor necrosis factor-alpha secretion through IKK regulation of NF-kappa B.

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12 December 2020

Neuroinflammation of the nigrostriatal pathway during progressive 6-OHDA dopamine degeneration in rats monitored by immunohistochemistry and PET imaging.

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12 December 2020

Activation of microglia by secreted amyloid precursor protein evokes release of glutamate by cystine exchange and attenuates synaptic function.

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12 December 2020

A specific p47phox -serine phosphorylated by convergent MAPKs mediates neutrophil NADPH oxidase priming at inflammatory sites

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12 December 2020

Macrophages in inflammation

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12 December 2020

IL-8 induces expression of matrix metalloproteinases, cell cycle and pro-apoptotic proteins, and cell death in cultured neurons.

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12 December 2020

Interleukin-10 protects against inflammation-mediated degeneration of dopaminergic neurons in substantia nigra

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12 December 2020

Alternative activation of macrophages

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12 December 2020

Potent anti-inflammatory and neuroprotective effects of TGF-beta1 are mediated through the inhibition of ERK and p47phox-Ser345 phosphorylation and translocation in microglia

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12 December 2020

Interleukin-10 protects lipopolysaccharide-induced neurotoxicity in primary midbrain cultures by inhibiting the function of NADPH oxidase

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12 December 2020

Cyclooxygenase-2 inhibitor ns-398 protects neuronal cultures from lipopolysaccharide-induced neurotoxicity

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12 December 2020

Transforming growth factor-beta suppresses activation and proliferation of microglia in vitro

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12 December 2020

Immunomodulatory effects of the alkaloid sinomenine in the high responder ACI-to-Lewis cardiac allograft model.

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12 December 2020

Glia-dependent neurotoxicity and neuroprotection in mesencephalic cultures

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12 December 2020

Pharmacology of sinomenine, an anti-rheumatic alkaloid from Sinomenium acutum

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12 December 2020

Parkinson's disease: mechanisms and models

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12 December 2020

Microglia, macrophages, perivascular macrophages, and pericytes: a review of function and identification

1 reference

12 December 2020

10.1007/S12026-008-8018-0

Identifiers

DOI

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23 December 2017

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23 December 2017