(Q36129331)

12 August 2017

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title

MPTP and SNpc DA neuronal vulnerability: role of dopamine, superoxide and nitric oxide in neurotoxicity. Minireview (English)

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12 August 2017

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Vernice Jackson-Lewis

series ordinal

1

object named as

Jackson-Lewis V

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12 August 2017

Smeyne RJ

2

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12 August 2017

publication date

1 January 2005

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12 August 2017

published in

Neurotoxicity Research

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12 August 2017

volume

7

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12 August 2017

issue

3

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12 August 2017

page(s)

193-202

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Dynamics of expression of the mRNA for cytokines and inducible nitric synthase in a murine model of the Parkinson's disease.

12 August 2017

cites work

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12 December 2020

The parkinsonian toxin MPTP: action and mechanism.

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12 December 2020

MPTP, MPP+ and mitochondrial function

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12 December 2020

Deficiencies in complex I subunits of the respiratory chain in Parkinson's disease

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12 December 2020

Astrocytes convert the parkinsonism inducing neurotoxin, MPTP, to its active metabolite, MPP+

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12 December 2020

Protective effects of neuronal nitric oxide synthase inhibitor in mouse brain against MPTP neurotoxicity: an immunohistological study

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12 December 2020

Levodopa prolongs life expectancy and is non-toxic to substantia nigra

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12 December 2020

NADPH oxidase mediates oxidative stress in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine model of Parkinson's disease

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12 December 2020

FcepsilonRII/CD23 is expressed in Parkinson's disease and induces, in vitro, production of nitric oxide and tumor necrosis factor-alpha in glial cells.

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12 December 2020

Pathogenic role of glial cells in Parkinson's disease.

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12 December 2020

Mitochondrial manganese superoxide dismutase prevents neural apoptosis and reduces ischemic brain injury: suppression of peroxynitrite production, lipid peroxidation, and mitochondrial dysfunction.

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12 December 2020

The oxidant stress hypothesis in Parkinson's disease: evidence supporting it

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12 December 2020

Neurotoxicity of MAO metabolites of catecholamine neurotransmitters: role in neurodegenerative diseases

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12 December 2020

Linkage between the proteasome pathway and neurodegenerative diseases and aging

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12 December 2020

Developmental neurobiology. The milieu is the message

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12 December 2020

Nitric oxide synthase and neuronal vulnerability in Parkinson's disease.

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12 December 2020

Peroxynitrite reactions and formation in mitochondria

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12 December 2020

Peroxynitrite-mediated oxidative protein modifications

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12 December 2020

Quantitation of 3,4-dihydroxyphenylacetaldehyde and 3, 4-dihydroxyphenylglycolaldehyde, the monoamine oxidase metabolites of dopamine and noradrenaline, in human tissues by microcolumn high-performance liquid chromatography

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12 December 2020

Time-course of the expression of inflammatory cytokines and matrix metalloproteinases in the striatum and mesencephalon of mice injected with 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine, a dopaminergic neurotoxin

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12 December 2020

The 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model: a tool to explore the pathogenesis of Parkinson's disease

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12 December 2020

1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) decreases glutamate uptake in cultured astrocytes

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12 December 2020

Mitochondrial dysfunction and reactive oxygen species in excitotoxicity and apoptosis: implications for the pathogenesis of neurodegenerative diseases

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12 December 2020

Cyclooxygenase-2: molecular biology, pharmacology, and neurobiology

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12 December 2020

Mitochondria, oxidative damage, and inflammation in Parkinson's disease

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12 December 2020

In vitro release of tritiated monoamines from rat CNS tissue by the neurotoxic compound 1-methyl-phenyl-tetrahydropyridine

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12 December 2020

Critical role of microglial NADPH oxidase-derived free radicals in the in vitro MPTP model of Parkinson's disease.

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12 December 2020

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12 December 2020

Depletion of striatal dopamine by the N-oxide of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP).

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12 December 2020

Cytotoxicity of microglia

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12 December 2020

Tyrosine hydroxylase and dopamine transporter expression following 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced neurodegeneration of the mouse nigrostriatal pathway

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12 December 2020

Genetic contributions to Parkinson's disease

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12 December 2020

3,4-Dihydroxyphenylacetaldehyde is the toxic dopamine metabolite in vivo: implications for Parkinson's disease pathogenesis

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12 December 2020

Superoxide radical and superoxide dismutases

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12 December 2020

Role of neuronal nitric oxide in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced dopaminergic neurotoxicity

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12 December 2020

Inactivation of tyrosine hydroxylase by nitration following exposure to peroxynitrite and 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP).

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12 December 2020

Time course and morphology of dopaminergic neuronal death caused by the neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine

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12 December 2020

Astrocytes as a primary locus for the conversion MPTP into MPP+

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12 December 2020

Deficiency of inducible nitric oxide synthase protects against MPTP toxicity in vivo

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12 December 2020

Tyrosine hydroxylase is inactivated by catechol-quinones and converted to a redox-cycling quinoprotein: possible relevance to Parkinson's disease.

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12 December 2020

A commentary on glial cell line-derived neurotrophic factor (GDNF). From a glial secreted molecule to gene therapy

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12 December 2020

Depletion of glial cell line-derived neurotrophic factor in substantia nigra neurons of Parkinson's disease brain

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12 December 2020

The protective role of levodopa in the human substantia nigra.

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12 December 2020

Absence of MPTP-induced neuronal death in mice lacking the dopamine transporter.

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12 December 2020

Changes in cytokines and neurotrophins in Parkinson's disease

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12 December 2020

Inducible nitric oxide synthase stimulates dopaminergic neurodegeneration in the MPTP model of Parkinson disease

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12 December 2020

Genetic clues to the pathogenesis of Parkinson's disease

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12 December 2020

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12 December 2020

Brain-derived growth factor and nerve growth factor concentrations are decreased in the substantia nigra in Parkinson's disease

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12 December 2020

Transgenic mice with increased Cu/Zn-superoxide dismutase activity are resistant to N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced neurotoxicity

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12 December 2020

Features of the dopaminergic neurotoxin MPTP.

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12 December 2020

Astroglial neurotrophic and neurite-promoting factors

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12 December 2020

Mitochondrial complex I deficiency in Parkinson's disease

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12 December 2020

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12 December 2020

Dopamine transporter is required for in vivo MPTP neurotoxicity: evidence from mice lacking the transporter.

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12 December 2020

Studies on the toxicity of 1-methyl-4-phenylpyridinium ion (MPP+) against mitochondria of mouse brain

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12 December 2020

Parkinsonism-inducing neurotoxin, N-methyl-4-phenyl-1,2,3,6 -tetrahydropyridine: uptake of the metabolite N-methyl-4-phenylpyridine by dopamine neurons explains selective toxicity

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12 December 2020

Inhibition of NADH-linked oxidation in brain mitochondria by 1-methyl-4-phenyl-pyridine, a metabolite of the neurotoxin, 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine

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12 December 2020

Cyclooxygenase 2 inhibition protects motor neurons and prolongs survival in a transgenic mouse model of ALS.

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12 December 2020

Neuroinflammatory processes in Parkinson's disease.

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12 December 2020

Etiology and pathogenesis of Parkinson's disease

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12 December 2020

Dose-dependent lesions of the dopaminergic nigrostriatal pathway induced by intrastriatal injection of 6-hydroxydopamine

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12 December 2020

Enzymatic oxidation of dopamine: the role of prostaglandin H synthase

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12 December 2020

Accumulation of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in cultured cerebellar astrocytes

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12 December 2020

Oxidative pathways for catecholamines in the genesis of neuromelanin and cytotoxic quinones

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12 December 2020

Evidence of active nerve cell degeneration in the substantia nigra of humans years after 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine exposure

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12 December 2020

Early and late molecular events in neurodegeneration and neuroprotection in Parkinson's disease MPTP model as assessed by cDNA microarray; the role of iron

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12 December 2020

Cyclooxygenase-2 is instrumental in Parkinson's disease neurodegeneration

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12 December 2020

Aggregated and monomeric alpha-synuclein bind to the S6' proteasomal protein and inhibit proteasomal function

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12 December 2020

Modulation of dihydroxyphenylacetaldehyde extracellular levels in vivo in the rat striatum after different kinds of pharmacological treatment

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12 December 2020

NADPH oxidase: an update

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12 December 2020

Manganese superoxide dismutase overexpression attenuates MPTP toxicity.

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12 December 2020

6-Hydroxydopamine Lesion of the Rat Substantia Nigra: Time Course and Morphology of Cell Death

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12 December 2020

Fatal attractions: abnormal protein aggregation and neuron death in Parkinson's disease and Lewy body dementia

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12 December 2020

Immunocytochemical co-localization of the proteasome in ubiquitinated structures in neurodegenerative diseases and the elderly.

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12 December 2020

Parkinson's disease: mechanisms and models

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12 December 2020

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12 December 2020

Identifiers

DOI

10.1007/BF03036449

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12 August 2017

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