(Q35913897)

11 August 2017

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title

Linkage between the proteasome pathway and neurodegenerative diseases and aging (English)

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11 August 2017

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Sophie Vigouroux

1

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11 August 2017

Marièle Briand

series ordinal

2

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11 August 2017

Yves Briand

series ordinal

3

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11 August 2017

publication date

1 October 2004

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11 August 2017

published in

Molecular Neurobiology

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11 August 2017

volume

30

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11 August 2017

issue

2

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11 August 2017

page(s)

201-221

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https://scigraph.springernature.com/pub.10.1385/mn:30:2:201

11 August 2017

exact match

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cites work

Protein degradation during aging: the lysosome-, the calpain- and the proteasome-dependent cellular proteolytic systems

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12 December 2020

Significance of the parkin gene and protein in understanding Parkinson's disease

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12 December 2020

Oxidative stress and aging in the Mongolian gerbil (Meriones unguiculatus)

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12 December 2020

Aging and proteolysis of oxidized proteins

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12 December 2020

Alteration of 20S proteasome-subtypes and proteasome activator PA28 in skeletal muscle of rat after induction of diabetes mellitus

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12 December 2020

Degradation of oxidized proteins in mammalian cells.

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12 December 2020

Hydrogen peroxide-mediated protein oxidation in young and old human MRC-5 fibroblasts.

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12 December 2020

Activation of the multicatalytic proteinase from rat skeletal muscle by fatty acids or sodium dodecyl sulphate

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12 December 2020

A novel ubiquitination factor, E4, is involved in multiubiquitin chain assembly.

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12 December 2020

Increased proteolytic activity in lymphocytes from patients with early onset Alzheimer's disease.

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12 December 2020

Identification of two distinct synucleins from human brain

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12 December 2020

Differences in Catalytic Activities and Subunit Pattern of Multicatalytic Proteinase Complexes (Proteasomes) Isolated from Bovine Pituitary, Lung, and Liver

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12 December 2020

The base of the proteasome regulatory particle exhibits chaperone-like activity

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12 December 2020

The function of the proteasome system in MHC class I antigen processing.

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12 December 2020

The proteasome activator 11 S REG (PA28) and class I antigen presentation

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12 December 2020

Proteasomes: multicatalytic proteinase complexes

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12 December 2020

The role of the ubiquitin-proteasomal pathway in Parkinson's disease and other neurodegenerative disorders

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12 December 2020

Degradation of oxidized proteins by the 20S proteasome.

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12 December 2020

Cleavage motifs of the yeast 20S proteasome beta subunits deduced from digests of enolase 1.

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12 December 2020

Protein oxidation and proteolysis during aging and oxidative stress

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12 December 2020

In vivo assembly of the proteasomal complexes, implications for antigen processing

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12 December 2020

Ubisemiquinone is the electron donor for superoxide formation by complex III of heart mitochondria

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12 December 2020

A subcomplex of the proteasome regulatory particle required for ubiquitin-conjugate degradation and related to the COP9-signalosome and eIF3.

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12 December 2020

Evidence for the presence of five distinct proteolytic components in the pituitary multicatalytic proteinase complex. Properties of two components cleaving bonds on the carboxyl side of branched chain and small neutral amino acids

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12 December 2020

Metabolism of the polyubiquitin degradation signal: structure, mechanism, and role of isopeptidase T

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12 December 2020

+1 Proteins and aging

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12 December 2020

The ubiquitin-mediated proteolytic pathway: mode of action and clinical implications

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12 December 2020

Role of the proteasome in Alzheimer's disease

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12 December 2020

Proteasome inhibitors induce cytochrome c-caspase-3-like protease-mediated apoptosis in cultured cortical neurons.

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12 December 2020

Familial Parkinson disease gene product, parkin, is a ubiquitin-protein ligase

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12 December 2020

Rat alpha-synuclein interacts with Tat binding protein 1, a component of the 26S proteasomal complex

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12 December 2020

Protein oxidation and degradation during proliferative senescence of human MRC-5 fibroblasts

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12 December 2020

Increased muscle proteasome activities in rats fed a polyunsaturated fatty acid supplemented diet

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12 December 2020

Increase of oxidatively modified protein is associated with a decrease of proteasome activity and content in aging epidermal cells

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12 December 2020

Subpopulations of proteasomes in rat liver nuclei, microsomes and cytosol

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12 December 2020

Incorporation of major histocompatibility complex – encoded subunits LMP2 and LMP7 changes the quality of the 20S proteasome polypeptide processing products independent of interferon‐γ

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12 December 2020

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12 December 2020

Dysfunction of mitochondrial complex I and the proteasome: interactions between two biochemical deficits in a cellular model of Parkinson's disease.

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12 December 2020

Impaired proteasome function in Alzheimer's disease

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12 December 2020

The calpain family and human disease

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12 December 2020

Gamma-interferon and expression of MHC genes regulate peptide hydrolysis by proteasomes

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12 December 2020

Dietary self-selection can compensate an age-related decrease of rat liver 20 S proteasome activity observed with standard diet

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12 December 2020

Aging of proteins and the proteasome.

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12 December 2020

Nuclear and mitochondrial genetics in Parkinson's disease.

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12 December 2020

Ala30Pro mutation in the gene encoding alpha-synuclein in Parkinson's disease

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12 December 2020

Hydrophobicity as the signal for selective degradation of hydroxyl radical-modified hemoglobin by the multicatalytic proteinase complex, proteasome

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12 December 2020

The proteasome, a novel protease regulated by multiple mechanisms

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12 December 2020

Regulation of proteasome complexes by gamma-interferon and phosphorylation

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12 December 2020

Distribution of proteasomes and of the five proteolytic activities in rat tissues

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12 December 2020

Transferring substrates to the 26S proteasome.

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12 December 2020

Proteasomal function is impaired in substantia nigra in Parkinson's disease

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12 December 2020

Ischemic neuronal death in the rat hippocampus: the calpain-calpastatin-caspase hypothesis

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12 December 2020

Oxidative DNA damage in the parkinsonian brain: an apparent selective increase in 8-hydroxyguanine levels in substantia nigra.

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12 December 2020

The sizes of peptides generated from protein by mammalian 26 and 20 S proteasomes. Implications for understanding the degradative mechanism and antigen presentation

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12 December 2020

Reactive oxygen species and the central nervous system

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12 December 2020

Mutant ubiquitin found in neurodegenerative disorders is a ubiquitin fusion degradation substrate that blocks proteasomal degradation

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12 December 2020

Additive effects of PS1 and APP mutations on secretion of the 42-residue amyloid beta-protein.

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12 December 2020

Binding of hydrophobic peptides to several non-catalytic sites promotes peptide hydrolysis by all active sites of 20 S proteasomes. Evidence for peptide-induced channel opening in the alpha-rings

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12 December 2020

Inducible expression of mutant alpha-synuclein decreases proteasome activity and increases sensitivity to mitochondria-dependent apoptosis

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12 December 2020

Hybrid proteasomes. Induction by interferon-gamma and contribution to ATP-dependent proteolysis

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12 December 2020

Presenilin 1 is actively degraded by the 26S proteasome.

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12 December 2020

Selective loss of 20S proteasome alpha-subunits in the substantia nigra pars compacta in Parkinson's disease

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12 December 2020

Proteasomes and proteasome inhibition in the central nervous system

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12 December 2020

Induction of protein catabolism and the ubiquitin-proteasome pathway by mild oxidative stress.

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12 December 2020

Brain proteasomal function in sporadic Parkinson's disease and related disorders

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12 December 2020

Formation of proteasome-PA700 complexes directly correlates with activation of peptidase activity

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12 December 2020

A gated channel into the proteasome core particle

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12 December 2020

Mutation in the alpha-synuclein gene identified in families with Parkinson's disease

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12 December 2020

Processing of the beta-amyloid precursor protein and its regulation in Alzheimer's disease

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12 December 2020

Contribution of proteasomal beta-subunits to the cleavage of peptide substrates analyzed with yeast mutants

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12 December 2020

PA200, a nuclear proteasome activator involved in DNA repair

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12 December 2020

Ubiquitination of a new form of alpha-synuclein by parkin from human brain: implications for Parkinson's disease

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12 December 2020

Accelerated in vitro fibril formation by a mutant alpha-synuclein linked to early-onset Parkinson disease

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12 December 2020

The proteasome in brain aging

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12 December 2020

Calpain activation in Huntington's disease.

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12 December 2020

Crystal structure of the 20S proteasome from the archaeon T. acidophilum at 3.4 A resolution

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12 December 2020

Antizyme, a mediator of ubiquitin-independent proteasomal degradation

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12 December 2020

Formation of stable complexes between two Alzheimer's disease gene products: presenilin-2 and beta-amyloid precursor protein

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12 December 2020

Lipid hydroperoxide generation, turnover, and effector action in biological systems

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12 December 2020

Decreased levels of proteasome activity and proteasome expression in aging spinal cord

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12 December 2020

Conversion of alpha-helices into beta-sheets features in the formation of the scrapie prion proteins

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12 December 2020

Peptidase activities of the 20/26S proteasome and a novel protease in human brain

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12 December 2020

Prevention of progression of Parkinson's disease with antioxidative therapy

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12 December 2020

Lactacystin, a specific inhibitor of the proteasome, induces apoptosis and activates caspase-3 in cultured cerebellar granule cells

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12 December 2020

The calpains in aging and aging-related diseases

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12 December 2020

C-terminal maturation fragments of presenilin 1 and 2 control secretion of APP alpha and A beta by human cells and are degraded by proteasome

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12 December 2020

The proteasome: paradigm of a self-compartmentalizing protease

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12 December 2020

The ubiquitin protein catabolic disorders.

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12 December 2020

Tissue distribution of constitutive proteasomes, immunoproteasomes, and PA28 in rats

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12 December 2020

Structure of 20S proteasome from yeast at 2.4 A resolution

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12 December 2020

Differential expression of ubiquitin and proteasome-dependent pathway components in rat tissues.

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12 December 2020

The unfolding of substrates and ubiquitin-independent protein degradation by proteasomes

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12 December 2020

Lobster muscle proteasome and the degradation of myofibrillar proteins.

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12 December 2020

Proteasome inhibition results in increased poly-ADP-ribosylation: implications for neuron death

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12 December 2020

Molecular misreading in non-neuronal cells.

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12 December 2020

Oxidative stress interference with the nuclear factor-kappa B activation pathways

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12 December 2020

(E)-4-hydroxy-2-nonenal may be involved in the pathogenesis of Parkinson's disease

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12 December 2020

Alpha-synuclein and the Parkinson's disease-related mutant Ala53Thr-alpha-synuclein do not undergo proteasomal degradation in HEK293 and neuronal cells

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12 December 2020

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12 December 2020

Protein oxidation and 20S proteasome-dependent proteolysis in mammalian cells

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12 December 2020

Immunohistochemical detection of 4-hydroxynonenal protein adducts in Parkinson disease

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12 December 2020

Reconstitution of hybrid proteasomes from purified PA700-20 S complexes and PA28alphabeta activator: ultrastructure and peptidase activities

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12 December 2020

Recognition of the polyubiquitin proteolytic signal

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12 December 2020

Role of the proteasome in protein oxidation and neural viability following low-level oxidative stress

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12 December 2020

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12 December 2020

Nigral and cortical Lewy bodies and dystrophic nigral neurites in Parkinson's disease and cortical Lewy body disease contain alpha-synuclein immunoreactivity.

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12 December 2020

Hydroxyl free radical adduct of deoxyguanosine: sensitive detection and mechanisms of formation

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12 December 2020

Ubiquitin in neurodegenerative diseases

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12 December 2020

Catalytic activities of the 20 S proteasome, a multicatalytic proteinase complex

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12 December 2020

Fibrils formed in vitro from alpha-synuclein and two mutant forms linked to Parkinson's disease are typical amyloid

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12 December 2020

The regulatory particle of the Saccharomyces cerevisiae proteasome.

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12 December 2020

The ubiquitin pathway in Parkinson's disease

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12 December 2020

Mechanisms underlying ubiquitination

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12 December 2020

The multicatalytic and 26 S proteases

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12 December 2020

Assays of proteasome activity in relation to aging

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12 December 2020

Selective degradation of oxidatively modified protein substrates by the proteasome.

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12 December 2020

Dityrosine and tyrosine oxidation products are endogenous markers for the selective proteolysis of oxidatively modified red blood cell hemoglobin by (the 19 S) proteasome.

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12 December 2020

Ataxin-1 with an expanded glutamine tract alters nuclear matrix-associated structures

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12 December 2020

Antigen processing by the proteasome

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12 December 2020

Subcellular localization of proteasomes and their regulatory complexes in mammalian cells.

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12 December 2020

The axial channel of the proteasome core particle is gated by the Rpt2 ATPase and controls both substrate entry and product release

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12 December 2020

The PRE4 gene codes for a subunit of the yeast proteasome necessary for peptidylglutamyl-peptide-hydrolyzing activity. Mutations link the proteasome to stress- and ubiquitin-dependent proteolysis.

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12 December 2020

Catalytic components of proteasomes and the regulation of proteinase activity.

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12 December 2020

Impairment of the ubiquitin-proteasome system causes dopaminergic cell death and inclusion body formation in ventral mesencephalic cultures

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12 December 2020

Endoproteolytic cleavage and proteasomal degradation of presenilin 2 in transfected cells

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12 December 2020

Possible involvement of proteasome inhibition in aging: implications for oxidative stress.

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12 December 2020

Oxidative modification of proteins during aging

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12 December 2020

Neurofibrillary tangles in progressive supranuclear palsy brains exhibit immunoreactivity to frameshift mutant ubiquitin-B protein

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12 December 2020

Ubiquitin conjugation is not required for the degradation of oxidized proteins by proteasome.

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12 December 2020

Protein oxidation and degradation during cellular senescence of human BJ fibroblasts: part I--effects of proliferative senescence

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12 December 2020

Proteasomes of the yeast S. cerevisiae: genes, structure and functions

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12 December 2020

Oxidation of free amino acids and amino acid residues in proteins by radiolysis and by metal-catalyzed reactions

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12 December 2020

Ubiquitin carboxyl-terminal hydrolase (PGP 9.5) is selectively present in ubiquitinated inclusion bodies characteristic of human neurodegenerative diseases.

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12 December 2020

Defective ubiquitination of cerebral proteins in Alzheimer's disease

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12 December 2020

alpha-synuclein metabolism and aggregation is linked to ubiquitin-independent degradation by the proteasome

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12 December 2020

The ubiquitin-proteasome proteolytic pathway: destruction for the sake of construction

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12 December 2020

Parkin suppresses unfolded protein stress-induced cell death through its E3 ubiquitin-protein ligase activity

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12 December 2020

Formation of neuronal intranuclear inclusions underlies the neurological dysfunction in mice transgenic for the HD mutation

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12 December 2020

Oxidative stress, aging and the proteasomal system

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12 December 2020

Inhibition of the ubiquitin-proteasome system in Alzheimer's disease.

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12 December 2020

A role for the ubiquitin-dependent proteolytic pathway in MHC class I-restricted antigen presentation

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12 December 2020

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12 December 2020

Roles of lipid peroxidation in modulation of cellular signaling pathways, cell dysfunction, and death in the nervous system

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12 December 2020

The role of tricorn protease and its aminopeptidase-interacting factors in cellular protein degradation

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12 December 2020

Immunocytochemical co-localization of the proteasome in ubiquitinated structures in neurodegenerative diseases and the elderly.

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12 December 2020

Reversal of age-related increase in brain protein oxidation, decrease in enzyme activity, and loss in temporal and spatial memory by chronic administration of the spin-trapping compound N-tert-butyl-alpha-phenylnitrone.

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12 December 2020

Proteasome involvement and accumulation of ubiquitinated proteins in cerebellar granule neurons undergoing apoptosis

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12 December 2020

PRE2, highly homologous to the human major histocompatibility complex-linked RING10 gene, codes for a yeast proteasome subunit necessary for chrymotryptic activity and degradation of ubiquitinated proteins

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12 December 2020

Identifiers

DOI

10.1385/MN:30:2:201

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Dimensions Publication ID

11 August 2017

1049349592

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