(Q46573639)

23 December 2017

title

UGT1A1 polymorphisms are important determinants of dietary carcinogen detoxification in the liver (English)

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23 December 2017

author

Chantal Guillemette

10

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23 December 2017

David J. Greenblatt

9

David J Greenblatt

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23 December 2017

Lisa L. von Moltke

8

Lisa L von Moltke

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23 December 2017

Michael H Court

3

Michael H Court

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23 December 2017

Lyne Villeneuve

5

Lyne Villeneuve

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23 December 2017

author name string

Hugo Girard

1

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23 December 2017

Jean Thibaudeau

2

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23 December 2017

Louis-Charles Fortier

4

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23 December 2017

Patrick Caron

6

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23 December 2017

Qin Hao

7

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23 December 2017

language of work or name

English

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publication date

1 August 2005

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23 December 2017

published in

Hepatology

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23 December 2017

volume

42

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23 December 2017

issue

2

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23 December 2017

page(s)

448-457

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23 December 2017

Cloning and stable expression of a new member of the human liver phenol/bilirubin: UDP-glucuronosyltransferase cDNA family

cites work

1 reference

Investigation of the substrate specificity of a cloned expressed human bilirubin UDP-glucuronosyltransferase: UDP-sugar specificity and involvement in steroid and xenobiotic glucuronidation

21 January 2018

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Estimation of dietary HCA intakes in a large-scale population-based prospective study in Japan

21 January 2018

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Activation of 2-hydroxyamino-1-methyl-6-phenylimidazo[4,5-b] pyridine by cDNA-expressed human and rat arylsulfotransferases.

21 January 2018

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Heterocyclic amines, meat intake, and association with colon cancer in a population-based study

21 January 2018

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7 January 2021

Colorectal cancer: molecules and populations

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7 January 2021

Generation of free radicals and induction of DNA adducts by activation of heterocyclic aromatic amines via different metabolic pathways in vitro.

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7 January 2021

The isolation and identification of a new mutagen from fried ground beef: 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP).

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7 January 2021

Carcinogenic heterocyclic amines in model systems and cooked foods: a review on formation, occurrence and intake.

1 reference

7 January 2021

The role of genetic polymorphisms in metabolism of carcinogenic heterocyclic aromatic amines

1 reference

7 January 2021

Differential metabolism of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine in rat and human hepatocytes

1 reference

7 January 2021

Identification of urine metabolites of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine following consumption of a single cooked chicken meal in humans

1 reference

7 January 2021

The identification of [2-(14)C]2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine metabolites in humans

1 reference

7 January 2021

Heterocyclic aromatic amines in human urine following a fried meat meal.

1 reference

7 January 2021

Excretion of the N(2)-glucuronide conjugate of 2-hydroxyamino-1-methyl-6-phenylimidazo[4,5-b]pyridine in urine and its relationship to CYP1A2 and NAT2 activity levels in humans

1 reference

7 January 2021

Concentration of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine (PhIP) in urine and alkali-hydrolyzed urine after consumption of charbroiled beef

1 reference

7 January 2021

Pharmacogenomics of human UDP-glucuronosyltransferase enzymes

1 reference

7 January 2021

Glucuronidation of 2-hydroxyamino-1-methyl-6-phenylimidazo[4, 5-b]pyridine by human microsomal UDP-glucuronosyltransferases: identification of specific UGT1A family isoforms involved.

1 reference

7 January 2021

N-glucuronidation of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) and N_hydroxy-PhIP by specific human UDP-glucuronosyltransferases

1 reference

7 January 2021

The UDP glycosyltransferase gene superfamily: recommended nomenclature update based on evolutionary divergence

1 reference

7 January 2021

The genetic basis of the reduced expression of bilirubin UDP-glucuronosyltransferase 1 in Gilbert's syndrome

1 reference

7 January 2021

Identification of a defect in the UGT1A1 gene promoter and its association with hyperbilirubinemia

1 reference

7 January 2021

Haplotype structure of the UDP-glucuronosyltransferase 1A1 promoter in different ethnic groups

1 reference

7 January 2021

Identification of common polymorphisms in the promoter of the UGT1A9 gene: evidence that UGT1A9 protein and activity levels are strongly genetically controlled in the liver.

1 reference

7 January 2021

Stereoselective conjugation of oxazepam by human UDP-glucuronosyltransferases (UGTs): S-oxazepam is glucuronidated by UGT2B15, while R-oxazepam is glucuronidated by UGT2B7 and UGT1A9

1 reference

7 January 2021

Pharmacogenetic determinants of interindividual variability in bupropion hydroxylation by cytochrome P450 2B6 in human liver microsomes

1 reference

7 January 2021

The functional UGT1A1 promoter polymorphism decreases endometrial cancer risk

1 reference

7 January 2021

PhIP metabolites in human urine after consumption of well-cooked chicken

1 reference

7 January 2021

Isolation and characterization of a human orphan UDP-glucuronosyltransferase, UGT2B11.

1 reference

7 January 2021

Racial variability in the UDP-glucuronosyltransferase 1 (UGT1A1) promoter: a balanced polymorphism for regulation of bilirubin metabolism?

1 reference

7 January 2021

Nutrition and colorectal cancer

1 reference

7 January 2021

Glucuronidation of N-hydroxy heterocyclic amines by human and rat liver microsomes.

1 reference

7 January 2021

In vivo human metabolism of [2-14C]2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP)

1 reference

7 January 2021

Cruciferous vegetable consumption alters the metabolism of the dietary carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) in humans

1 reference

7 January 2021

Liquid chromatography-tandem mass spectrometry method of urine analysis for determining human variation in carcinogen metabolism

1 reference

7 January 2021

Formation of a glutathione conjugate and a semistable transportable glucuronide conjugate of N2-oxidized species of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) in rat liver

1 reference

7 January 2021

N-and O-acetylation of aromatic and heterocyclic amine carcinogens by human monomorphic and polymorphic acetyltransferases expressed in COS-1 cells

1 reference

7 January 2021

Identification of defect in the genes for bilirubin UDP-glucuronosyl-transferase in a patient with Crigler-Najjar syndrome type II

1 reference

7 January 2021

Genetic variants in the UDP-glucuronosyltransferase 1A1 gene predict the risk of severe neutropenia of irinotecan

1 reference

7 January 2021

Two linked polymorphic mutations (A(TA)7TAA and T-3279G) of UGT1A1 as the principal cause of Gilbert syndrome

1 reference

7 January 2021

Urinary mutagenesis and fried red meat intake: influence of cooking temperature, phenotype, and genotype of metabolizing enzymes in a controlled feeding study

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7 January 2021

Identifiers

DOI

10.1002/HEP.20770

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23 December 2017

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23 December 2017