(Q46597560)

23 December 2017

title

Targeted disruption of p53 attenuates doxorubicin-induced cardiac toxicity in mice (English)

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23 December 2017

Omar Y Mian

3

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author name string

Yukitaka Shizukuda

1

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23 December 2017

Satoaki Matoba

2

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23 December 2017

Tammy Nguyen

4

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23 December 2017

Paul M Hwang

5

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23 December 2017

publication date

1 May 2005

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23 December 2017

Molecular and Cellular Biochemistry

published in

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23 December 2017

volume

273

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23 December 2017

issue

1-2

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23 December 2017

page(s)

25-32

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23 December 2017

https://scigraph.springernature.com/pub.10.1007/s11010-005-5905-8

exact match

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cites work

Pacing-induced heart failure in dogs enhances the expression of p53 and p53-dependent genes in ventricular myocytes

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS11010-005-5905-8

Insulin-like growth factor-1 induces Mdm2 and down-regulates p53, attenuating the myocyte renin-angiotensin system and stretch-mediated apoptosis

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS11010-005-5905-8

The effect of dexrazoxane on myocardial injury in doxorubicin-treated children with acute lymphoblastic leukemia

21 January 2018

1 reference

12 December 2020

A model for p53-induced apoptosis

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12 December 2020

p53 regulates mitochondrial membrane potential through reactive oxygen species and induces cytochrome c-independent apoptosis blocked by Bcl-2.

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12 December 2020

Adriamycin-induced early changes in myocardial antioxidant enzymes and their modulation by probucol

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12 December 2020

p53 tagged sites from human genomic DNA.

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12 December 2020

Anthracyclines in the treatment of cancer. An overview

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12 December 2020

beta-adrenergic stimulation causes cardiocyte apoptosis: influence of tachycardia and hypertrophy

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12 December 2020

Echocardiographic assessment of left ventricular mass and systolic function in mice

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12 December 2020

Stretch-mediated release of angiotensin II induces myocyte apoptosis by activating p53 that enhances the local renin-angiotensin system and decreases the Bcl-2-to-Bax protein ratio in the cell

1 reference

12 December 2020

Doxorubicin and vinorelbine act independently via p53 expression and p38 activation respectively in breast cancer cell lines

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12 December 2020

Prevention of doxorubicin myocardial toxicity in mice by reduced glutathione

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12 December 2020

Cell-cycle arrest versus cell death in cancer therapy

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12 December 2020

Apoptosis in adriamycin cardiomyopathy and its modulation by probucol

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12 December 2020

Effects of water-soluble antioxidant from spinach, NAO, on doxorubicin-induced heart injury

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12 December 2020

Suppression of p53: a new approach to overcome side effects of antitumor therapy

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12 December 2020

Regulation of p53 stability by Mdm2

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12 December 2020

The chemical inducibility of mouse cardiac antioxidants and phase 2 enzymes in vivo

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12 December 2020

Downregulation of protein kinase cdelta activity enhances endothelial cell adaptation to hypoxia

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12 December 2020

p53 Induces myocyte apoptosis via the activation of the renin-angiotensin system.

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12 December 2020

Pifithrin-alpha protects against doxorubicin-induced apoptosis and acute cardiotoxicity in mice

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12 December 2020

In vivo echocardiographic detection of enhanced left ventricular function in gene-targeted mice with phospholamban deficiency

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12 December 2020

Mdm2 promotes the rapid degradation of p53

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12 December 2020

A preoperative diagnostic test that distinguishes benign from malignant thyroid carcinoma based on gene expression

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12 December 2020

Attenuation of the acute adriamycin-induced cardiac and hepatic oxidative toxicity by N-(2-mercaptopropionyl) glycine in rats

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12 December 2020

Anthracycline-induced cardiotoxicity

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12 December 2020

Doxorubicin-induced apoptosis in endothelial cells and cardiomyocytes is ameliorated by nitrone spin traps and ebselen. Role of reactive oxygen and nitrogen species

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12 December 2020

Daunorubicin-induced apoptosis in rat cardiac myocytes is inhibited by dexrazoxane

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12 December 2020

Adriamycin-induced heart failure: mechanism and modulation

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12 December 2020

Echocardiographic and cardiac Doppler assessment of mice

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12 December 2020

Oxidative damage of sulfur dioxide on various organs of mice: sulfur dioxide is a systemic oxidative damage agent

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12 December 2020

Doxorubicin induces apoptosis and CD95 gene expression in human primary endothelial cells through a p53-dependent mechanism.

1 reference

12 December 2020

Ferredoxin reductase affects p53-dependent, 5-fluorouracil-induced apoptosis in colorectal cancer cells

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12 December 2020

Myocyte apoptosis during acute myocardial infarction in the mouse localizes to hypoxic regions but occurs independently of p53

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12 December 2020

Reactive oxygen species are downstream mediators of p53-dependent apoptosis

1 reference

12 December 2020

S-allylcysteine ameliorates doxorubicin toxicity in the heart and liver in mice

1 reference

12 December 2020

Surfing the p53 network

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12 December 2020

Evidence for a p53‐independent pathway for upregulation of SDI1/CIP1/WAF1/P21 RNA in human cells

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12 December 2020

Doxorubicin/taxane combinations: cardiac toxicity and pharmacokinetics

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12 December 2020

Protection against acute adriamycin-induced cardiotoxicity by garlic: role of endogenous antioxidants and inhibition of TNF-alpha expression

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12 December 2020

p53 and the hypoxia-induced apoptosis of cultured neonatal rat cardiac myocytes

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12 December 2020

Donor cardiac allografts from p53 knockout mice exhibit apoptosis-independent prolongation of survival

1 reference

12 December 2020

10.1007/S11010-005-5905-8

Identifiers

DOI

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23 December 2017

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23 December 2017