(Q46602642)

23 December 2017

title

Disruption of the hexokinase-VDAC complex for tumor therapy (English)

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23 December 2017

1

L Galluzzi

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23 December 2017

O Kepp

2

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Guido Kroemer

object named as

G Kroemer

series ordinal

4

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author name string

N Tajeddine

series ordinal

3

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23 December 2017

language of work or name

English

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publication date

12 May 2008

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23 December 2017

published in

Oncogene

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23 December 2017

volume

27

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23 December 2017

issue

34

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23 December 2017

page(s)

4633-4635

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23 December 2017

https://scigraph.springernature.com/pub.10.1038/onc.2008.114

exact match

0 references

cites work

Bcl-2-regulated apoptosis: mechanism and therapeutic potential

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.114

A high-throughput screening for mammalian cell death effectors identifies the mitochondrial phosphate carrier as a regulator of cytochrome c release.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.114

Protein kinase Cepsilon interacts with and inhibits the permeability transition pore in cardiac mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.114

Complexes between porin, hexokinase, mitochondrial creatine kinase and adenylate translocator display properties of the permeability transition pore. Implication for regulation of permeability transition by the kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.114

The permeability transition pore complex in cancer cell death

21 January 2018

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Chemotherapy: targeting the mitochondrial cell death pathway

21 January 2018

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Mitochondria--the suicide organelles

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2008.114

Mitochondria as therapeutic targets for cancer chemotherapy

21 January 2018

1 reference

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Suppression of adenine nucleotide translocase-2 by vector-based siRNA in human breast cancer cells induces apoptosis and inhibits tumor growth in vitro and in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.114

Mitochondrial membrane permeabilization in cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.114

Caspase-independent cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.114

Chemosensitization by knockdown of adenine nucleotide translocase-2.

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2008.114

Programmed anuclear cell death delimits platelet life span.

21 January 2018

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Akt mediates mitochondrial protection in cardiomyocytes through phosphorylation of mitochondrial hexokinase-II.

21 January 2018

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An inhibitor of Bcl-2 family proteins induces regression of solid tumours

21 January 2018

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Warburg, me and Hexokinase 2: Multiple discoveries of key molecular events underlying one of cancers' most common phenotypes, the "Warburg Effect", i.e., elevated glycolysis in the presence of oxygen

21 January 2018

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Mitochondrial hexokinases, novel mediators of the antiapoptotic effects of growth factors and Akt.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.114

Glucose phosphorylation and mitochondrial binding are required for the protective effects of hexokinases I and II.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.114

The adenine nucleotide translocator: a target of nitric oxide, peroxynitrite, and 4-hydroxynonenal

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.114

Bid acts on the permeability transition pore complex to induce apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.114

Methyl jasmonate binds to and detaches mitochondria-bound hexokinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.114

Activation of glycogen synthase kinase 3beta disrupts the binding of hexokinase II to mitochondria by phosphorylating voltage-dependent anion channel and potentiates chemotherapy-induced cytotoxicity

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.114

31 March 2020

Identifiers

DOI

10.1038/ONC.2008.114

1 reference

23 December 2017

1 reference

23 December 2017