(Q46648320)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18407920%20AND%20SRC:MED&resulttype=core&format=json

5 January 2020

title

De novo CoA biosynthesis is required to maintain DNA integrity during development of the Drosophila nervous system (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18407920%20AND%20SRC:MED&resulttype=core&format=json

5 January 2020

0 references

1 reference

ChEBI release 2020-05-28

ChEBI ID

15346

Bifunctional Phosphopantetheine adenylyltransferase - Dephospho-CoA kinase Dmel_CG10575

1 reference

GOA release 2020-03-11

author

Harm H Kampinga

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18407920%20AND%20SRC:MED&resulttype=core&format=json

5 January 2020

author name string

Floris Bosveld

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18407920%20AND%20SRC:MED&resulttype=core&format=json

5 January 2020

Anil Rana

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18407920%20AND%20SRC:MED&resulttype=core&format=json

5 January 2020

Petra E van der Wouden

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18407920%20AND%20SRC:MED&resulttype=core&format=json

5 January 2020

Willy Lemstra

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18407920%20AND%20SRC:MED&resulttype=core&format=json

5 January 2020

Martha Ritsema

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18407920%20AND%20SRC:MED&resulttype=core&format=json

5 January 2020

Ody C M Sibon

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18407920%20AND%20SRC:MED&resulttype=core&format=json

5 January 2020

publication date

10 April 2008

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18407920%20AND%20SRC:MED&resulttype=core&format=json

5 January 2020

published in

Human Molecular Genetics

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18407920%20AND%20SRC:MED&resulttype=core&format=json

5 January 2020

volume

17

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18407920%20AND%20SRC:MED&resulttype=core&format=json

5 January 2020

issue

13

1 reference

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5 January 2020

page(s)

2058-2069

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18407920%20AND%20SRC:MED&resulttype=core&format=json

Drosophila as a model for human neurodegenerative disease

5 January 2020

cites work

1 reference

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Complete reconstitution of the human coenzyme A biosynthetic pathway via comparative genomics

21 January 2018

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4'-phosphopantetheine and coenzyme A biosynthesis in plants.

21 January 2018

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Phosphopantothenoylcysteine synthetase from Escherichia coli. Identification and characterization of the last unidentified coenzyme A biosynthetic enzyme in bacteria

21 January 2018

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A novel pantothenate kinase gene (PANK2) is defective in Hallervorden-Spatz syndrome

21 January 2018

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PINK, PANK, or PARK? A clinicians' guide to familial parkinsonism

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Mitochondrial dysfunction and oxidative stress in neurodegenerative diseases

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Unraveling the Hallervorden-Spatz syndrome: pantothenate kinase-associated neurodegeneration is the name

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Neurodegeneration with brain iron accumulation, type 1 is characterized by alpha-, beta-, and gamma-synuclein neuropathology

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Iron misregulation in the brain: a primary cause of neurodegenerative disorders

21 January 2018

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Deficiency of pantothenate kinase 2 (Pank2) in mice leads to retinal degeneration and azoospermia

21 January 2018

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Coenzyme A biosynthesis: reconstruction of the pathway in archaea and an evolutionary scenario based on comparative genomics

21 January 2018

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Coenzyme A: back in action

21 January 2018

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Preventing neurodegeneration in the Drosophila mutant bubblegum

21 January 2018

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The neurodegeneration mutant löchrig interferes with cholesterol homeostasis and Appl processing

21 January 2018

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Loss of Swiss cheese/neuropathy target esterase activity causes disruption of phosphatidylcholine homeostasis and neuronal and glial death in adult Drosophila

21 January 2018

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Altered neuronal mitochondrial coenzyme A synthesis in neurodegeneration with brain iron accumulation caused by abnormal processing, stability, and catalytic activity of mutant pantothenate kinase 2

21 January 2018

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Activation of human mitochondrial pantothenate kinase 2 by palmitoylcarnitine

21 January 2018

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Chemical knockout of pantothenate kinase reveals the metabolic and genetic program responsible for hepatic coenzyme A homeostasis

21 January 2018

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Neurodegenerative mutants in Drosophila: a means to identify genes and mechanisms involved in human diseases?

21 January 2018

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Pink1, Parkin, DJ-1 and mitochondrial dysfunction in Parkinson's disease

21 January 2018

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Loss of glial lazarillo, a homolog of apolipoprotein D, reduces lifespan and stress resistance in Drosophila

21 January 2018

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Overexpression of a Drosophila homolog of apolipoprotein D leads to increased stress resistance and extended lifespan

21 January 2018

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Effects of Overexpression of Copper-Zinc and Manganese Superoxide Dismutases, Catalase, and Thioredoxin Reductase Genes on Longevity in Drosophila melanogaster

21 January 2018

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Toxic DNA damage by hydrogen peroxide through the Fenton reaction in vivo and in vitro

21 January 2018

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Disruption of Drosophila Rad50 causes pupal lethality, the accumulation of DNA double-strand breaks and the induction of apoptosis in third instar larvae

21 January 2018

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The contribution of the DNA damage response to neuronal viability

21 January 2018

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Histone H2A variants H2AX and H2AZ

21 January 2018

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Megabase chromatin domains involved in DNA double-strand breaks in vivo

21 January 2018

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Purification and properties of D-pantothenate kinase from rat liver.

21 January 2018

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Hallervorden-Spatz disease: cysteine accumulation and cysteine dioxygenase deficiency in the globus pallidus

21 January 2018

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Compound heterozygous PANK2 mutations confirm HARP and Hallervorden-Spatz syndromes are allelic

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Drosophila Med6 is required for elevated expression of a large but distinct set of developmentally regulated genes

21 January 2018

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Enigma, a mitochondrial protein affecting lifespan and oxidative stress response in Drosophila

21 January 2018

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