(Q36269243)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16187075%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

review article

1 reference

title

Neurodegenerative mutants in Drosophila: a means to identify genes and mechanisms involved in human diseases? (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16187075%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

0 references

1 reference

1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16187075%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

author name string

Doris Kretzschmar

series ordinal

1

1 reference

13 August 2017

publication date

24 October 2005

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16187075%20AND%20SRC:MED&resulttype=core&format=json

Invertebrate Neuroscience

7 January 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16187075%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

volume

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16187075%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

issue

3-4

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16187075%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

page(s)

97-109

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16187075%20AND%20SRC:MED&resulttype=core&format=json

Developmental and metabolic regulation of the Drosophila melanogaster 3-hydroxy-3-methylglutaryl coenzyme A reductase

7 January 2020

cites work

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS10158-005-0005-8

Motor neuron disease (amyotrophic lateral sclerosis).

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS10158-005-0005-8

Amyotrophic lateral sclerosis and structural defects in Cu,Zn superoxide dismutase

21 January 2018

1 reference

12 December 2020

Neuromuscular defects in a Drosophila survival motor neuron gene mutant.

1 reference

12 December 2020

Mapping of Behaviour in Drosophila Mosaics

1 reference

12 December 2020

A genetic screen for mutations that disrupt an auditory response in Drosophila melanogaster

1 reference

12 December 2020

A model for studying Alzheimer's Abeta42-induced toxicity in Drosophila melanogaster

1 reference

12 December 2020

Polyglutamine expansion, protein aggregation, proteasome activity, and neural survival.

1 reference

12 December 2020

Selective loss of glial glutamate transporter GLT‐1 in amyotrophic lateral sclerosis

1 reference

12 December 2020

An update of the mutation spectrum of the survival motor neuron gene (SMN1) in autosomal recessive spinal muscular atrophy (SMA).

1 reference

12 December 2020

Loss of poly(ADP-ribose) glycohydrolase causes progressive neurodegeneration in Drosophila melanogaster

1 reference

12 December 2020

Inhibition of apoptosis by Z-VAD-fmk in SMN-depleted S2 cells

1 reference

12 December 2020

Dissecting the pathological effects of human Abeta40 and Abeta42 in Drosophila: a potential model for Alzheimer's disease

1 reference

12 December 2020

Deregulation of the Egfr/Ras signaling pathway induces age-related brain degeneration in the Drosophila mutant vap.

1 reference

12 December 2020

blue cheese mutations define a novel, conserved gene involved in progressive neural degeneration.

1 reference

12 December 2020

Subunit-destabilizing mutations in Drosophila copper/zinc superoxide dismutase: neuropathology and a model of dimer dysequilibrium

1 reference

12 December 2020

Progress in X-linked adrenoleukodystrophy

1 reference

12 December 2020

The neurodegeneration mutant löchrig interferes with cholesterol homeostasis and Appl processing

1 reference

12 December 2020

Androgens, andropause and neurodegeneration: exploring the link between steroidogenesis, androgens and Alzheimer's disease

1 reference

12 December 2020

Genetic basis of tolerance to O2 deprivation in Drosophila melanogaster

1 reference

12 December 2020

Tau and tau reporters disrupt central projections of sensory neurons in Drosophila.

1 reference

12 December 2020

Drosophila fragile X-related gene regulates the MAP1B homolog Futsch to control synaptic structure and function

1 reference

12 December 2020

Neural dysfunction and neurodegeneration in Drosophila Na+/K+ ATPase alpha subunit mutants.

1 reference

12 December 2020

Loss of neuropathy target esterase in mice links organophosphate exposure to hyperactivity

1 reference

12 December 2020

Membrane dynamics, cholesterol homeostasis, and Alzheimer's disease

1 reference

12 December 2020

Defective glia in the Drosophila brain degeneration mutant drop-dead

1 reference

12 December 2020

ADAMs family members as amyloid precursor protein alpha-secretases

1 reference

12 December 2020

Molecular basis of Alzheimer's disease

1 reference

12 December 2020

Flies on steroids--Drosophila metamorphosis and the mechanisms of steroid hormone action

1 reference

12 December 2020

Acyl-coenzyme A: cholesterol acyltransferase modulates the generation of the amyloid beta-peptide

1 reference

12 December 2020

Imaging of amyloid-beta deposits in brains of living mice permits direct observation of clearance of plaques with immunotherapy.

1 reference

12 December 2020

Expanded polyglutamine peptides disrupt EGF receptor signaling and glutamate transporter expression in Drosophila.

1 reference

12 December 2020

Age-dependent neurodegeneration and Alzheimer-amyloid plaque formation in transgenic Drosophila.

1 reference

12 December 2020

Early-onset epilepsy and postnatal lethality associated with an editing-deficient GluR-B allele in mice

1 reference

12 December 2020

Chaperone suppression of alpha-synuclein toxicity in a Drosophila model for Parkinson's disease

1 reference

12 December 2020

Arrestin: roles in the life and death of retinal neurons

1 reference

12 December 2020

Very long-chain acyl-CoA synthetases. Human "bubblegum" represents a new family of proteins capable of activating very long-chain fatty acids

1 reference

12 December 2020

Neuronal ceroid lipofuscinoses caused by defects in soluble lysosomal enzymes (CLN1 and CLN2)

1 reference

12 December 2020

Spongecake and eggroll: two hereditary diseases in Drosophila resemble patterns of human brain degeneration

1 reference

12 December 2020

Phospholipid signaling

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12 December 2020

Phosphorylation of alpha-synuclein characteristic of synucleinopathy lesions is recapitulated in alpha-synuclein transgenic Drosophila

1 reference

12 December 2020

The Drosophila carbonyl reductase sniffer prevents oxidative stress-induced neurodegeneration.

1 reference

12 December 2020

Cytoskeletal mechanisms of neuronal degeneration.

1 reference

12 December 2020

Expanded polyglutamine protein forms nuclear inclusions and causes neural degeneration in Drosophila

1 reference

12 December 2020

Palmitoyl protein thioesterase 1 is targeted to the axons in neurons

1 reference

12 December 2020

Modelling human diseases in Drosophila and Caenorhabditis

1 reference

12 December 2020

Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis

1 reference

12 December 2020

The aggravating role of the ubiquitin-proteasome system in neurodegeneration

1 reference

12 December 2020

The structural brain mutant Vacuolar medulla of Drosophila melanogaster with specific behavioral defects and cell degeneration in the adult

1 reference

12 December 2020

Organophosphates and delayed neuropathy--is NTE alive and well?

1 reference

12 December 2020

Novel mechanism of massive photoreceptor degeneration caused by mutations in the trp gene of Drosophila.

1 reference

12 December 2020

Palmitoyl protein thioesterase 1 protects against apoptosis mediated by Ras-Akt-caspase pathway in neuroblastoma cells

1 reference

12 December 2020

Cholesterol and Alzheimer's disease: statins, cholesterol depletion in APP processing and Abeta generation.

1 reference

12 December 2020

Apoptosis mediated by phosphatidylcholine-specific phospholipase C is associated with cAMP, p53 level, and cell-cycle distribution in vascular endothelial cells

1 reference

12 December 2020

Lipid composition in different regions of the brain in Alzheimer's disease/senile dementia of Alzheimer's type

1 reference

12 December 2020

HSpin1, a transmembrane protein interacting with Bcl-2/Bcl-xL, induces a caspase-independent autophagic cell death

1 reference

12 December 2020

Transgenic Drosophila expressing human amyloid precursor protein show gamma-secretase activity and a blistered-wing phenotype

1 reference

12 December 2020

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12 December 2020

Membrane breakdown in acute and chronic neurodegeneration: focus on choline-containing phospholipids

1 reference

12 December 2020

Identification of genes that modify ataxin-1-induced neurodegeneration.

1 reference

12 December 2020

Neurosteroids: of the nervous system, by the nervous system, for the nervous system.

1 reference

12 December 2020

Identification, secretion, and neural expression of APPL, a Drosophila protein similar to human amyloid protein precursor

1 reference

12 December 2020

Loss of Swiss cheese/neuropathy target esterase activity causes disruption of phosphatidylcholine homeostasis and neuronal and glial death in adult Drosophila

1 reference

12 December 2020

Retinitis pigmentosa and allied diseases. Implications of genetic heterogeneity.

1 reference

12 December 2020

Light activation, adaptation, and cell survival functions of the Na+/Ca2+ exchanger CalX.

1 reference

12 December 2020

Disruption of the MAP1B-related protein FUTSCH leads to changes in the neuronal cytoskeleton, axonal transport defects, and progressive neurodegeneration in Drosophila

1 reference

12 December 2020

A role for Caenorhabditis elegans in understanding the function and interactions of human disease genes

1 reference

12 December 2020

Phospholipid membrane composition affects EGF receptor and Notch signaling through effects on endocytosis during Drosophila development

1 reference

12 December 2020

Tauopathy in Drosophila: neurodegeneration without neurofibrillary tangles

1 reference

12 December 2020

Modeling human neurodegenerative diseases in Drosophila: on a wing and a prayer.

1 reference

12 December 2020

Ecdysone receptor expression in the CNS correlates with stage-specific responses to ecdysteroids during Drosophila and Manduca development.

1 reference

12 December 2020

The synaptic vesicle cycle: a cascade of protein-protein interactions

1 reference

12 December 2020

Neurodegeneration: diseases of the cytoskeleton?

1 reference

12 December 2020

Neuropathy target esterase and its yeast homologue degrade phosphatidylcholine to glycerophosphocholine in living cells

1 reference

12 December 2020

A-to-I pre-mRNA editing in Drosophila is primarily involved in adult nervous system function and integrity

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12 December 2020

Induction of antioxidative and antiapoptotic thioredoxin supports neuroprotective hypothesis of estrogen

1 reference

12 December 2020

AMP-activated protein kinase, a metabolic master switch: possible roles in type 2 diabetes

1 reference

12 December 2020

The AMP-activated/SNF1 protein kinase subfamily: metabolic sensors of the eukaryotic cell?

1 reference

12 December 2020

Dying for a cause: invertebrate genetics takes on human neurodegeneration

1 reference

12 December 2020

The Drosophila beta-amyloid precursor protein homolog promotes synapse differentiation at the neuromuscular junction.

1 reference

12 December 2020

RNA editing of brain glutamate receptor channels: mechanism and physiology

1 reference

12 December 2020

Tau, where are we now?

1 reference

12 December 2020

Placental failure and impaired vasculogenesis result in embryonic lethality for neuropathy target esterase-deficient mice

1 reference

12 December 2020

Leber congenital amaurosis and retinitis pigmentosa with Coats-like exudative vasculopathy are associated with mutations in the crumbs homologue 1 (CRB1) gene

1 reference

12 December 2020

Preventing neurodegeneration in the Drosophila mutant bubblegum

1 reference

12 December 2020

Mutations in the novel membrane protein spinster interfere with programmed cell death and cause neural degeneration in Drosophila melanogaster

1 reference

12 December 2020

Promoters and promotion of axonopathies

1 reference

12 December 2020

Neural development and neurodegeneration: two faces of neuropathy target esterase

1 reference

12 December 2020

RNA editing in brain controls a determinant of ion flow in glutamate-gated channels

1 reference

12 December 2020

The dare gene: steroid hormone production, olfactory behavior, and neural degeneration in Drosophila.

1 reference

12 December 2020

Retinal degeneration caused by dominant rhodopsin mutations in Drosophila.

1 reference

12 December 2020

Neural disease: Drosophila degenerates for a good cause

1 reference

12 December 2020

Vascular system defects and neuronal apoptosis in mice lacking ras GTPase-activating protein

1 reference

12 December 2020

Amyloid beta peptide alters intracellular vesicle trafficking and cholesterol homeostasis

1 reference

12 December 2020

Increased brain protein levels of carbonyl reductase and alcohol dehydrogenase in Down syndrome and Alzheimer's disease

1 reference

12 December 2020

A Drosophila homolog of the polyglutamine disease gene SCA2 is a dosage-sensitive regulator of actin filament formation

1 reference

12 December 2020

Protein domains, catalytic activity, and subcellular distribution of neuropathy target esterase in Mammalian cells

1 reference

12 December 2020

Understanding the molecular responses to hypoxia using Drosophila as a genetic model

1 reference

12 December 2020

Drosophila Crumbs is a positional cue in photoreceptor adherens junctions and rhabdomeres

1 reference

12 December 2020

Polyglutamine-expanded human huntingtin transgenes induce degeneration of Drosophila photoreceptor neurons.

1 reference

12 December 2020

An over-expression system for characterizing Ppt1 function in Drosophila

1 reference

12 December 2020

Unrestricted synaptic growth in spinster-a late endosomal protein implicated in TGF-beta-mediated synaptic growth regulation.

1 reference

12 December 2020

Physiology, phylogeny, and functions of the TRP superfamily of cation channels

1 reference

12 December 2020

Brain-specific deletion of neuropathy target esterase/swisscheese results in neurodegeneration

1 reference

12 December 2020

A very long-chain acyl-CoA synthetase-deficient mouse and its relevance to X-linked adrenoleukodystrophy

1 reference

12 December 2020

A Drosophila model of Parkinson's disease

1 reference

12 December 2020

Superoxide dismutase evolution and life span regulation

1 reference

12 December 2020

The AMP-activated protein kinase pathway--new players upstream and downstream.

1 reference

12 December 2020

Photoreceptor cells in flies and mammals: Crumby homology?

1 reference

12 December 2020

TRP gating is linked to the metabolic state and maintenance of the Drosophila photoreceptor cells

1 reference

12 December 2020

Characterization of AMP-activated protein kinase gamma-subunit isoforms and their role in AMP binding

1 reference

12 December 2020

Temperature-sensitive paralytic mutants are enriched for those causing neurodegeneration in Drosophila.

1 reference

12 December 2020

Pathology of the adult central nervous system induced by genetic inhibition of programmed cell death in Drosophila pupae.

1 reference

12 December 2020

Untangling tau-related dementia

1 reference

12 December 2020

Neurodegenerative tauopathies

1 reference

12 December 2020

Progressive neurodegeneration in Drosophila: a model system

1 reference

12 December 2020

Decreasing glutamate buffering capacity triggers oxidative stress and neuropil degeneration in the Drosophila brain.

1 reference

12 December 2020

Molecular cloning and structural analysis of 3-hydroxy-3-methylglutaryl coenzyme A reductase of the moth Agrotis ipsilon

1 reference

12 December 2020

CRB1 has a cytoplasmic domain that is functionally conserved between human and Drosophila

1 reference

12 December 2020

From fruit fly to bedside: translating lessons from Drosophila models of neurodegenerative disease

1 reference

12 December 2020

Conserved responses to oxygen deprivation

1 reference

12 December 2020

Crumbs, the Drosophila homologue of human CRB1/RP12, is essential for photoreceptor morphogenesis

1 reference

12 December 2020

Alfy, a novel FYVE-domain-containing protein associated with protein granules and autophagic membranes

1 reference

12 December 2020

Dealing with energy demand: the AMP-activated protein kinase

1 reference

12 December 2020

Defective intracellular transport is the molecular basis of rhodopsin-dependent dominant retinal degeneration

1 reference

12 December 2020

Alzheimer's Abeta1-40 peptide modulates lipid synthesis in neuronal cultures and intact rat fetal brain under normoxic and oxidative stress conditions

1 reference

12 December 2020

Novel dominant rhodopsin mutation triggers two mechanisms of retinal degeneration and photoreceptor desensitization.

1 reference

12 December 2020

Analysis of tauopathies with transgenic mice

1 reference

12 December 2020

Regulatory role of dADAR in ROS metabolism in Drosophila CNS.

1 reference

12 December 2020

The pathogenesis of organophosphate polyneuropathy.

1 reference

12 December 2020

Structural determinants of ion flow through recombinant glutamate receptor channels

1 reference

12 December 2020

The role of PAR-1 in regulating the polarised microtubule cytoskeleton in the Drosophila follicular epithelium

1 reference

12 December 2020

Human wild-type tau interacts with wingless pathway components and produces neurofibrillary pathology in Drosophila

1 reference

12 December 2020

Neurological dysfunctions in mice expressing different levels of the Q/R site-unedited AMPAR subunit GluR-B.

1 reference

12 December 2020

Human neurodegenerative disease modeling using Drosophila.

1 reference

12 December 2020

X-linked adrenoleukodystrophy: genes, mutations, and phenotypes

1 reference

12 December 2020

Isoprenoids control germ cell migration downstream of HMGCoA reductase

1 reference

12 December 2020

Remodeling of the insect nervous system

1 reference

12 December 2020

Mutations in the palmitoyl protein thioesterase gene causing infantile neuronal ceroid lipofuscinosis

1 reference

12 December 2020

Cellular defenses against unfolded proteins: a cell biologist thinks about neurodegenerative diseases

1 reference

12 December 2020

Determinants of Ca2+ permeability in both TM1 and TM2 of high affinity kainate receptor channels: diversity by RNA editing

1 reference

12 December 2020

Proteolytic processing and cell biological functions of the amyloid precursor protein

1 reference

12 December 2020

10.1007/S10158-005-0005-8

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16187075%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

1 reference