(Q46715578)

24 December 2017

title

Pharmacokinetic and behavioral effects of allopregnanolone in healthy women (English)

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24 December 2017

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Inger Sundström-Poromaa

10

object named as

Inger Sundström Poromaa

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Olav Spigset

4

object named as

Olav Spigset

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24 December 2017

Torbjörn C. Bäckström

9

object named as

Torbjörn Bäckström

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24 December 2017

author name string

Erika Timby

1

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24 December 2017

Matts Balgård

2

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24 December 2017

Sigrid Nyberg

3

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24 December 2017

Agneta Andersson

5

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24 December 2017

Joanna Porankiewicz-Asplund

6

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24 December 2017

Robert H Purdy

7

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24 December 2017

Di Zhu

8

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24 December 2017

publication date

21 September 2005

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24 December 2017

published in

Psychopharmacology

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24 December 2017

volume

186

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24 December 2017

issue

3

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24 December 2017

page(s)

414-424

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24 December 2017

https://scigraph.springernature.com/pub.10.1007/s00213-005-0148-7

exact match

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cites work

Quantitative measurement of saccade amplitude, duration, and velocity

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Effects of antidepressant treatment on neuroactive steroids in major depression

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Reduced benzodiazepine sensitivity in panic disorder

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Short-term exposure to a neuroactive steroid increases alpha4 GABA(A) receptor subunit levels in association with increased anxiety in the female rat

21 January 2018

1 reference

12 December 2020

Lack of influence of menstrual cycle and premenstrual syndrome diagnosis on pregnanolone pharmacokinetics.

1 reference

12 December 2020

Patients with premenstrual syndrome have a different sensitivity to a neuroactive steroid during the menstrual cycle compared to control subjects.

1 reference

12 December 2020

Efficacy of progesterone and progestogens in management of premenstrual syndrome: systematic review

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12 December 2020

Dynamic aspects of acute tolerance to allopregnanolone evaluated using anaesthesia threshold in male rats.

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12 December 2020

Determination of progesterone and some of its neuroactive ring A-reduced metabolites in human serum

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12 December 2020

Pharmacokinetics and pharmacodynamics of eltanolone (pregnanolone), a new steroid intravenous anaesthetic, in humans

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12 December 2020

The human corpus luteum secretes 5 alpha-pregnane-3,20-dione

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12 December 2020

Physiological aspects of steroids with anaesthetic properties

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12 December 2020

Neurosteroids and reward: allopregnanolone produces a conditioned place aversion in rats.

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12 December 2020

A putative receptor for neurosteroids on the GABAA receptor complex: the pharmacological properties and therapeutic potential of epalons

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12 December 2020

Altered sensitivity to alcohol in the late luteal phase among patients with premenstrual dysphoric disorder

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12 December 2020

Steroid hormone metabolites are barbiturate-like modulators of the GABA receptor

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12 December 2020

Allopregnanolone in women with premenstrual syndrome.

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12 December 2020

Anxiolytic effects of the neuroactive steroid pregnanolone (3 alpha-OH-5 beta-pregnan-20-one) after microinjection in the dorsal hippocampus and lateral septum.

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12 December 2020

Allopregnanolone concentrations and premenstrual syndrome.

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12 December 2020

Effect of progesterone and its 5 alpha and 5 beta metabolites on symptoms of premenstrual syndrome according to route of administration

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12 December 2020

Cortical gamma-aminobutyric acid levels across the menstrual cycle in healthy women and those with premenstrual dysphoric disorder: a proton magnetic resonance spectroscopy study

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12 December 2020

Patients with premenstrual syndrome have decreased saccadic eye velocity compared to control subjects.

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12 December 2020

Sensitivity to a neurosteroid is increased during addition of progestagen to postmenopausal hormone replacement therapy

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12 December 2020

GABA(A) receptor-modulating neuroactive steroid composition in patients with panic disorder before and during paroxetine treatment

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12 December 2020

Treatment of premenstrual syndrome by spironolactone: a double-blind, placebo-controlled study

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12 December 2020

Rewarding effect of the neuroactive steroid 3 alpha-hydroxy-5 alpha-pregnan-20-one in mice.

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12 December 2020

Anxiolytic activity of the progesterone metabolite 5α-pregnan-3α-ol-20-one

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12 December 2020

Gamma-aminobutyric acidA receptor regulation: chronic treatment with pregnanolone uncouples allosteric interactions between steroid and benzodiazepine recognition sites.

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12 December 2020

Down-regulation of the GABA receptor subunits mRNA levels in mammalian cultured cortical neurons following chronic neurosteroid treatment.

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12 December 2020

Neurosteroid metabolism in the human brain

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12 December 2020

Identification and characterization of a pregnane steroid recognition site that is functionally coupled to an expressed GABAA receptor

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12 December 2020

Reduced benzodiazepine sensitivity in patients with premenstrual syndrome: a pilot study.

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12 December 2020

The role of GABAergic neuroactive steroids in ethanol action, tolerance and dependence

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12 December 2020

Modulation of the GABA receptor complex by a steroid anaesthetic

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12 December 2020

The effect of a low dose of alcohol on allopregnanolone serum concentrations across the menstrual cycle in women with severe premenstrual syndrome and controls

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12 December 2020

Progesterone metabolite allopregnanolone in women with premenstrual syndrome

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12 December 2020

Chronic neurosteroid treatment attenuates single cell GABAA response and its potentiation by modulators in cortical neurons.

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12 December 2020

The anaesthetic potency of 3 alpha-hydroxy-5 alpha-pregnan-20-one and 3 alpha-hydroxy-5 beta-pregnan-20-one determined with an intravenous EEG-threshold method in male rats.

1 reference

12 December 2020

Circulating levels of allopregnanolone in humans: gender, age, and endocrine influences

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12 December 2020

Allopregnanolone levels and reactivity to mental stress in premenstrual dysphoric disorder

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12 December 2020

Alcohol Intoxication Increases Allopregnanolone Levels in Female Adolescent Humans

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12 December 2020

Neurosteroids mediate pharmacological effects of ethanol: a new mechanism of ethanol action?

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12 December 2020

Utility of a new procedure for diagnosing mental disorders in primary care. The PRIME-MD 1000 study

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12 December 2020

Estradiol and the addition of progesterone increase the sensitivity to a neurosteroid in postmenopausal women

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12 December 2020

Interaction between 3 alpha-hydroxy-5 alpha-pregnan-20-one and carbachol in the control of neuronal excitability in hippocampal slices of female rats in defined phases of the oestrus.

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12 December 2020

Allopregnanolone and pregnanolone are produced by the human corpus luteum

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12 December 2020

Vaginal administration of allopregnanolone to postmenopausal women undergoing estrogen replacement therapy: preliminary results

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12 December 2020

Evaluation and comparison of the pharmacokinetic and pharmacodynamic properties of allopregnanolone and pregnanolone at induction of anaesthesia in the male rat.

1 reference

12 December 2020

Anxiolytic Effect of Progesterone is Mediated by the Neurosteroid Allopregnanolone at Brain GABAA Receptors

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12 December 2020

Influence of route of administration on progesterone metabolism

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12 December 2020

Concentrations of progesterone and the 5 alpha-reduced progestins, 5 alpha-pregnane-3,20-dione and 3 alpha-hydroxy-5 alpha-pregnan-20-one, in luteal tissue and circulating blood and their relationship to luteal function in the African elephant, Loxo

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12 December 2020

Clinical applications of visual analogue scales: a critical review.

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12 December 2020

Pregnanolone emulsion. A preliminary pharmacokinetic and pharmacodynamic study of a new intravenous anaesthetic agent.

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12 December 2020

Pharmacology of saccadic eye movements in man. 2. Effects of the alpha 2-adrenoceptor ligands idazoxan and clonidine

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12 December 2020

Serum concentrations of some neuroactive steroids in women suffering from mixed anxiety-depressive disorder.

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12 December 2020

Allopregnanolone affects sleep in a benzodiazepine-like fashion.

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12 December 2020

Neuroactive steroids, their precursors and polar conjugates during parturition and postpartum in maternal blood: 2. Time profiles of pregnanolone isomers

1 reference

12 December 2020

Neuroactive steroids, their precursors, and polar conjugates during parturition and postpartum in maternal and umbilical blood: 1. Identification and simultaneous determination of pregnanolone isomers.

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12 December 2020

Anxiolytic effects of 3α-hydroxy-5α[β]-pregnan-20-one: endogenous metabolites of progesterone that are active at the GABAA receptor

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12 December 2020

Relationship between symptom severity and steroid variation in women with premenstrual syndrome: study on serum pregnenolone, pregnenolone sulfate, 5 alpha-pregnane-3,20-dione and 3 alpha-hydroxy-5 alpha-pregnan-20-one.

1 reference

12 December 2020

Radioimmunoassay of 3 alpha-hydroxy-5 alpha-pregnan-20-one in rat and human plasma.

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12 December 2020

Circulating levels of anxiolytic steroids in the luteal phase in women with premenstrual syndrome and in control subjects.

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12 December 2020

Relationship between allopregnanolone and negative mood in postmenopausal women taking sequential hormone replacement therapy with vaginal progesterone

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12 December 2020

Neuroactive pregnanolone isomers during pregnancy.

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12 December 2020

Serum allopregnanolone levels in pregnant women: changes during pregnancy, at delivery, and in hypertensive patients.

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12 December 2020

Anxiolytic metabolites of progesterone: correlation with mood and performance measures following oral progesterone administration to healthy female volunteers.

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12 December 2020

3beta-20beta-dihydroxy-5alpha-pregnane (UC1011) antagonism of the GABA potentiation and the learning impairment induced in rats by allopregnanolone

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12 December 2020

10.1007/S00213-005-0148-7

Identifiers

DOI

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24 December 2017

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24 December 2017