(Q46727259)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29224783%20AND%20SRC:MED&resulttype=core&format=json

6 April 2020

title

In Vivo Target Gene Activation via CRISPR/Cas9-Mediated Trans-epigenetic Modulation (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29224783%20AND%20SRC:MED&resulttype=core&format=json

6 April 2020

0 references

0 references

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29224783%20AND%20SRC:MED&resulttype=core&format=json

6 April 2020

Masahiro Sakurai

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29224783%20AND%20SRC:MED&resulttype=core&format=json

6 April 2020

Li-Fan Lu

14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29224783%20AND%20SRC:MED&resulttype=core&format=json

6 April 2020

author name string

Hsin-Kai Liao

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29224783%20AND%20SRC:MED&resulttype=core&format=json

6 April 2020

Fumiyuki Hatanaka

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29224783%20AND%20SRC:MED&resulttype=core&format=json

6 April 2020

Toshikazu Araoka

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29224783%20AND%20SRC:MED&resulttype=core&format=json

6 April 2020

Min-Zu Wu

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29224783%20AND%20SRC:MED&resulttype=core&format=json

6 April 2020

Yinghui Sui

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29224783%20AND%20SRC:MED&resulttype=core&format=json

6 April 2020

Takayoshi Yamauchi

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29224783%20AND%20SRC:MED&resulttype=core&format=json

6 April 2020

David D O'Keefe

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29224783%20AND%20SRC:MED&resulttype=core&format=json

6 April 2020

Estrella Núñez-Delicado

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29224783%20AND%20SRC:MED&resulttype=core&format=json

6 April 2020

Pedro Guillen

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29224783%20AND%20SRC:MED&resulttype=core&format=json

6 April 2020

Josep M Campistol

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29224783%20AND%20SRC:MED&resulttype=core&format=json

6 April 2020

Cheng-Jang Wu

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29224783%20AND%20SRC:MED&resulttype=core&format=json

6 April 2020

Concepcion Rodriguez Esteban

15

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29224783%20AND%20SRC:MED&resulttype=core&format=json

6 April 2020

Juan Carlos Izpisua Belmonte

16

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29224783%20AND%20SRC:MED&resulttype=core&format=json

6 April 2020

language of work or name

English

0 references

publication date

7 December 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29224783%20AND%20SRC:MED&resulttype=core&format=json

6 April 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29224783%20AND%20SRC:MED&resulttype=core&format=json

6 April 2020

volume

171

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29224783%20AND%20SRC:MED&resulttype=core&format=json

6 April 2020

issue

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29224783%20AND%20SRC:MED&resulttype=core&format=json

6 April 2020

page(s)

1495-1507.e15

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29224783%20AND%20SRC:MED&resulttype=core&format=json

describes a project that uses

6 April 2020

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC5732045/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

Repurposing CRISPR System for Transcriptional Activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5732045

Unexpected mutations after CRISPR–Cas9 editing in vivo

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5732045

Integration of CpG-free DNA induces de novo methylation of CpG islands in pluripotent stem cells.

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5732045

Marked for death: targeting epigenetic changes in cancer

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5732045

CRISPR-Based Technologies for the Manipulation of Eukaryotic Genomes

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5732045

In vivo genome editing via CRISPR/Cas9 mediated homology-independent targeted integration

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5732045

A multifunctional AAV-CRISPR-Cas9 and its host response

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5732045

3D Culture Supports Long-Term Expansion of Mouse and Human Nephrogenic Progenitors

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5732045

Next stop for the CRISPR revolution: RNA-guided epigenetic regulators

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5732045

Epigenetic drugs: from chemistry via biology to medicine and back

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5732045

Comparison of Cas9 activators in multiple species

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5732045

Klotho gene silencing promotes pathology in the mdx mouse model of Duchenne muscular dystrophy

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5732045

Correlation of Utrophin Levels with the Dystrophin Protein Complex and Muscle Fibre Regeneration in Duchenne and Becker Muscular Dystrophy Muscle Biopsies

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5732045

Editing the epigenome: technologies for programmable transcription and epigenetic modulation

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5732045

In vivo gene editing in dystrophic mouse muscle and muscle stem cells

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5732045

In vivo genome editing improves muscle function in a mouse model of Duchenne muscular dystrophy.

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5732045

Postnatal genome editing partially restores dystrophin expression in a mouse model of muscular dystrophy.

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5732045

Orthogonal gene knockout and activation with a catalytically active Cas9 nuclease

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5732045

The New State of the Art: Cas9 for Gene Activation and Repression

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5732045

Cas9 gRNA engineering for genome editing, activation and repression.

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5732045

Duchenne muscular dystrophy: current cell therapies

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5732045

Use of the CRISPR/Cas9 system as an intracellular defense against HIV-1 infection in human cells

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5732045

Renal progenitors derived from human iPSCs engraft and restore function in a mouse model of acute kidney injury

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5732045

Synthetic epigenetics-towards intelligent control of epigenetic states and cell identity

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5732045

Highly efficient Cas9-mediated transcriptional programming

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5732045

The second coming of epigenetic drugs: a more strategic and broader research framework could boost the development of new drugs to modify epigenetic factors and gene expression

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5732045

Use of epigenetic drugs in disease: an overview

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5732045

Genome-scale transcriptional activation by an engineered CRISPR-Cas9 complex

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5732045

Intravenous injections in neonatal mice

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5732045

In vivo interrogation of gene function in the mammalian brain using CRISPR-Cas9

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5732045

A protein-tagging system for signal amplification in gene expression and fluorescence imaging

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5732045

Genome-Scale CRISPR-Mediated Control of Gene Repression and Activation

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5732045

Intracerebroventricular viral injection of the neonatal mouse brain for persistent and widespread neuronal transduction

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5732045

CRISPR-Cas9 knockin mice for genome editing and cancer modeling

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5732045

Derivation and characterization of mouse embryonic stem cells from permissive and nonpermissive strains

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5732045

Cas9 effector-mediated regulation of transcription and differentiation in human pluripotent stem cells

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5732045

Klotho has dual protective effects on cisplatin-induced acute kidney injury

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5732045

Orthogonal Cas9 proteins for RNA-guided gene regulation and editing

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5732045

RNA-guided gene activation by CRISPR-Cas9-based transcription factors

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5732045

CRISPR-mediated modular RNA-guided regulation of transcription in eukaryotes

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5732045

Interleukin-10 deficiency aggravates kidney inflammation and fibrosis in the unilateral ureteral obstruction mouse model

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5732045

Repurposing CRISPR as an RNA-guided platform for sequence-specific control of gene expression

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5732045

Epigenetic Editing: targeted rewriting of epigenetic marks to modulate expression of selected target genes

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5732045

A Programmable Dual-RNA-Guided DNA Endonuclease in Adaptive Bacterial Immunity

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5732045

A transcription activator-like effector toolbox for genome engineering

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5732045

An essential protective role of IL-10 in the immunological mechanism underlying resistance vs. susceptibility to lupus induction by dendritic cells and dying cells

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5732045

Genome-wide profiling of the core clock protein BMAL1 targets reveals a strict relationship with metabolism

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5732045

Six2 defines and regulates a multipotent self-renewing nephron progenitor population throughout mammalian kidney development

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5732045

Analysis of AAV serotypes 1-9 mediated gene expression and tropism in mice after systemic injection

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5732045

Long-term enhancement of skeletal muscle mass and strength by single gene administration of myostatin inhibitors

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5732045

Reprogramming liver-stem WB cells into functional insulin-producing cells by persistent expression of Pdx1- and Pdx1-VP16 mediated by lentiviral vectors

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5732045

Suppression of aging in mice by the hormone Klotho

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5732045

Pancreatic and duodenal homeobox gene 1 induces expression of insulin genes in liver and ameliorates streptozotocin-induced hyperglycemia

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5732045

A second promoter provides an alternative target for therapeutic up-regulation of utrophin in Duchenne muscular dystrophy

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5732045

Skeletal muscle-specific expression of a utrophin transgene rescues utrophin-dystrophin deficient mice.

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5732045

The molecular basis of muscular dystrophy in the mdx mouse: a point mutation

29 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/29224783

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Amelioration of the dystrophic phenotype of mdx mice using a truncated utrophin transgene

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/29224783

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.CELL.2017.10.025

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29224783%20AND%20SRC:MED&resulttype=core&format=json

6 April 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29224783%20AND%20SRC:MED&resulttype=core&format=json

6 April 2020

PubMed publication ID

29224783

1 reference