(Q46739909)

24 December 2017

title

Geldanamycin induces heat shock protein 70 and protects against MPTP-induced dopaminergic neurotoxicity in mice (English)

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24 December 2017

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Hai-Ying Shen

1

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24 December 2017

Jin-Cai He

2

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24 December 2017

Yumei Wang

3

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24 December 2017

Qing-Yuan Huang

4

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24 December 2017

Jiang-Fan Chen

5

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24 December 2017

language of work or name

English

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publication date

6 October 2005

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24 December 2017

Journal of Biological Chemistry

published in

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24 December 2017

volume

280

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24 December 2017

issue

48

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24 December 2017

page(s)

39962-39969

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24 December 2017

Parkinson's disease: mechanisms and models

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Regulation of Aging and Age-Related Disease by DAF-16 and Heat-Shock Factor

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Geldanamycin induces heat shock proteins in brain and protects against focal cerebral ischemia

21 January 2018

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Differential neuroprotection from human heat shock protein 70 overexpression in in vitro and in vivo models of ischemia and ischemia-like conditions

21 January 2018

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Mice overexpressing 70-kDa heat shock protein show increased resistance to malonate and 3-nitropropionic acid

21 January 2018

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Heat shock protein 27 prevents cellular polyglutamine toxicity and suppresses the increase of reactive oxygen species caused by huntingtin

21 January 2018

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Hsp70 exerts its anti-apoptotic function downstream of caspase-3-like proteases.

21 January 2018

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Geldanamycin provides posttreatment protection against glutamate-induced oxidative toxicity in a mouse hippocampal cell line

21 January 2018

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Geldanamycin activates a heat shock response and inhibits huntingtin aggregation in a cell culture model of Huntington's disease

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Over-expression of inducible HSP70 chaperone suppresses neuropathology and improves motor function in SCA1 mice

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Hsp70 Reduces alpha-Synuclein Aggregation and Toxicity

21 January 2018

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Geldanamycin induces Hsp70 and prevents alpha-synuclein aggregation and toxicity in vitro

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Geldanamycin restores a defective heat shock response in vivo

21 January 2018

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Distinct promoters regulate tissue-specific and differential expression of kallikrein 6 in CNS demyelinating disease

21 January 2018

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Geldanamycin treatment inhibits hemorrhage-induced increases in KLF6 and iNOS expression in unresuscitated mouse organs: role of inducible HSP70.

21 January 2018

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Chaperoning brain degeneration

21 January 2018

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Heat shock-induced accumulation of 70-kDa stress protein (HSP70) can protect ATP-depleted tumor cells from necrosis.

21 January 2018

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Lack of neuroprotection by heat shock protein 70 overexpression in a mouse model of global cerebral ischemia.

21 January 2018

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Overexpression of heat shock protein 70 in R6/2 Huntington's disease mice has only modest effects on disease progression

21 January 2018

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Chaperone suppression of cellular toxicity of huntingtin is independent of polyglutamine aggregation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M505524200

21 January 2018

Identifiers

DOI

10.1074/JBC.M505524200

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24 December 2017

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24 December 2017