(Q35913771)

11 August 2017

1 reference

title

Hsp90: the vulnerable chaperone (English)

1 reference

11 August 2017

0 references

1

Gabriela Chiosis

0 references

author name string

Maria Vilenchik

series ordinal

2

1 reference

11 August 2017

Joungnam Kim

series ordinal

3

1 reference

11 August 2017

David Solit

series ordinal

4

1 reference

11 August 2017

publication date

1 October 2004

1 reference

11 August 2017

1 reference

11 August 2017

volume

9

1 reference

11 August 2017

issue

20

1 reference

11 August 2017

page(s)

881-888

1 reference

Hsp70 and Hsp90--a relay team for protein folding

11 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2804%2903245-3

7 January 2021

Molecular chaperones and the stress of oncogenesis

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2804%2903245-3

7 January 2021

Therapeutic and diagnostic implications of Hsp90 activation

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2804%2903245-3

7 January 2021

A high-affinity conformation of Hsp90 confers tumour selectivity on Hsp90 inhibitors

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2804%2903245-3

7 January 2021

Targeting wide-range oncogenic transformation via PU24FCl, a specific inhibitor of tumor Hsp90.

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2804%2903245-3

7 January 2021

Regulation of survivin function by Hsp90

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2804%2903245-3

7 January 2021

Modulation of Akt kinase activity by binding to Hsp90

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2804%2903245-3

7 January 2021

Disruption of the Raf-1-Hsp90 Molecular Complex Results in Destabilization of Raf-1 and Loss of Raf-1-Ras Association

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2804%2903245-3

7 January 2021

Disruption of hsp90 function results in degradation of the death domain kinase, receptor-interacting protein (RIP), and blockage of tumor necrosis factor-induced nuclear factor-kappaB activation

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2804%2903245-3

7 January 2021

Heat shock protein 90 suppresses tumor necrosis factor alpha induced apoptosis by preventing the cleavage of Bid in NIH3T3 fibroblasts

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2804%2903245-3

7 January 2021

Negative regulation of cytochrome c-mediated oligomerization of Apaf-1 and activation of procaspase-9 by heat shock protein 90

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2804%2903245-3

7 January 2021

Hsp90 inhibitors as novel cancer chemotherapeutic agents

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2804%2903245-3

7 January 2021

HSP90 as a new therapeutic target for cancer therapy: the story unfolds

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2804%2903245-3

7 January 2021

Inhibition of Hsp90: a new strategy for inhibiting protein kinases

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2804%2903245-3

7 January 2021

Identification and structural characterization of the ATP/ADP-binding site in the Hsp90 molecular chaperone

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2804%2903245-3

7 January 2021

ATPases as drug targets: learning from their structure

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2804%2903245-3

7 January 2021

Crystal structure of an Hsp90-geldanamycin complex: targeting of a protein chaperone by an antitumor agent

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2804%2903245-3

7 January 2021

Geldanamycin as a potential anti-cancer agent: its molecular target and biochemical activity

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2804%2903245-3

7 January 2021

Geldanamycin-induced destabilization of Raf-1 involves the proteasome

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2804%2903245-3

7 January 2021

The benzoquinone ansamycin 17-allylamino-17-demethoxygeldanamycin binds to HSP90 and shares important biologic activities with geldanamycin

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2804%2903245-3

7 January 2021

DT-Diaphorase expression and tumor cell sensitivity to 17-allylamino, 17-demethoxygeldanamycin, an inhibitor of heat shock protein 90

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2804%2903245-3

7 January 2021

Clinical Development of 17-Allylamino, 17-Demethoxygeldanamycin

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2804%2903245-3

7 January 2021

Pharmacokinetics, tissue distribution, and metabolism of 17-(dimethylaminoethylamino)-17-demethoxygeldanamycin (NSC 707545) in CD2F1 mice and Fischer 344 rats

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2804%2903245-3

7 January 2021

Antiangiogenic properties of 17-(dimethylaminoethylamino)-17-demethoxygeldanamycin: an orally bioavailable heat shock protein 90 modulator

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2804%2903245-3

7 January 2021

17-(Allylamino)-17-demethoxygeldanamycin activity in human melanoma models

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2804%2903245-3

7 January 2021

Antibiotic radicicol binds to the N-terminal domain of Hsp90 and shares important biologic activities with geldanamycin

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2804%2903245-3

7 January 2021

Structural basis for inhibition of the Hsp90 molecular chaperone by the antitumor antibiotics radicicol and geldanamycin

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2804%2903245-3

7 January 2021

Development of Radicicol Analogues

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2804%2903245-3

7 January 2021

A small molecule designed to bind to the adenine nucleotide pocket of Hsp90 causes Her2 degradation and the growth arrest and differentiation of breast cancer cells

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2804%2903245-3

7 January 2021

Development of a purine-scaffold novel class of Hsp90 binders that inhibit the proliferation of cancer cells and induce the degradation of Her2 tyrosine kinase

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2804%2903245-3

7 January 2021

Development of Purine-Scaffold Small Molecule Inhibitors of Hsp90

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2804%2903245-3

7 January 2021

Structure-activity relationships in purine-based inhibitor binding to HSP90 isoforms

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2804%2903245-3

7 January 2021

High-throughput screening assay for inhibitors of heat-shock protein 90 ATPase activity

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2804%2903245-3

7 January 2021

The C-terminal half of heat shock protein 90 represents a second site for pharmacologic intervention in chaperone function

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2804%2903245-3

7 January 2021

The heat shock protein 90 antagonist novobiocin interacts with a previously unrecognized ATP-binding domain in the carboxyl terminus of the chaperone

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2804%2903245-3

7 January 2021

Novobiocin and related coumarins and depletion of heat shock protein 90-dependent signaling proteins

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2804%2903245-3

7 January 2021

A Nucleotide-dependent molecular switch controls ATP binding at the C-terminal domain of Hsp90. N-terminal nucleotide binding unmasks a C-terminal binding pocket

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2804%2903245-3

7 January 2021

A novel chaperone-activity-reducing mechanism of the 90-kDa molecular chaperone HSP90.

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2804%2903245-3

7 January 2021

The heat shock protein 90-targeting drug cisplatin selectively inhibits steroid receptor activation

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2804%2903245-3

7 January 2021

Reactive cysteines of the 90-kDa heat shock protein, Hsp90

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2804%2903245-3

7 January 2021

Hsp90 phosphorylation is linked to its chaperoning function. Assembly of the reovirus cell attachment protein

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2804%2903245-3

7 January 2021

Modulation of p53, ErbB1, ErbB2, and Raf-1 expression in lung cancer cells by depsipeptide FR901228

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2804%2903245-3

7 January 2021

Hsp90 as a capacitor for morphological evolution

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2804%2903245-3

7 January 2021

10.1016/S1359-6446(04)03245-3

Identifiers

DOI

1 reference

11 August 2017

1 reference