(Q46767416)

25 December 2017

title

Metabonomic analysis identifies molecular changes associated with the pathophysiology and drug treatment of bipolar disorder (English)

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25 December 2017

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9

S Bahn

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25 December 2017

M J Lan

1

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25 December 2017

G A McLoughlin

2

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25 December 2017

J L Griffin

3

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25 December 2017

T M Tsang

4

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25 December 2017

J T J Huang

5

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25 December 2017

P Yuan

6

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25 December 2017

H Manji

7

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25 December 2017

E Holmes

8

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25 December 2017

language of work or name

English

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publication date

5 February 2008

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25 December 2017

published in

Molecular Psychiatry

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25 December 2017

volume

14

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25 December 2017

issue

3

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25 December 2017

page(s)

269-279

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25 December 2017

https://scigraph.springernature.com/pub.10.1038/sj.mp.4002130

exact match

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cites work

Cross-national epidemiology of major depression and bipolar disorder

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Valproic acid reduces brain damage induced by transient focal cerebral ischemia in rats: potential roles of histone deacetylase inhibition and heat shock protein induction

21 January 2018

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Valproic acid, a mood stabilizer and anticonvulsant, protects rat cerebral cortical neurons from spontaneous cell death: a role of histone deacetylase inhibition

21 January 2018

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Chronic lithium treatment robustly protects neurons in the central nervous system against excitotoxicity by inhibiting N-methyl-D-aspartate receptor-mediated calcium influx

21 January 2018

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Chronic treatment with a low dose of lithium protects the brain against ischemic injury by reducing apoptotic death

21 January 2018

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The mood-stabilizing agents lithium and valproate robustly increase the levels of the neuroprotective protein bcl-2 in the CNS

21 January 2018

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1H magnetic resonance spectroscopy investigation of the dorsolateral prefrontal cortex in bipolar disorder patients

21 January 2018

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Mood stabilizers target cellular plasticity and resilience cascades: implications for the development of novel therapeutics

21 January 2018

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'Metabonomics': understanding the metabolic responses of living systems to pathophysiological stimuli via multivariate statistical analysis of biological NMR spectroscopic data

21 January 2018

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Metabolic characterization of distinct neuroanatomical regions in rats by magic angle spinning 1H nuclear magnetic resonance spectroscopy

21 January 2018

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Metabolic profiling of CSF: evidence that early intervention may impact on disease progression and outcome in schizophrenia

21 January 2018

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Mitochondrial dysfunction in schizophrenia: evidence for compromised brain metabolism and oxidative stress

21 January 2018

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Metabolic profiling of plasma from discordant schizophrenia twins: correlation between lipid signals and global functioning in female schizophrenia patients.

21 January 2018

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CSF metabolic and proteomic profiles in patients prodromal for psychosis

21 January 2018

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Quantification of neurons in Alzheimer and control brains with ex vivo high resolution magic angle spinning proton magnetic resonance spectroscopy and stereology

21 January 2018

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Metabolic characterization of the R6/2 transgenic mouse model of Huntington's disease by high-resolution MAS 1H NMR spectroscopy

21 January 2018

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High resolution 1H NMR-based metabolomics indicates a neurotransmitter cycling deficit in cerebral tissue from a mouse model of Batten disease

21 January 2018

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The application of NMR-based metabonomics in neurological disorders

21 January 2018

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Analytical strategies in metabonomics

21 January 2018

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The functional neuroanatomy of bipolar disorder: a review of neuroimaging findings

21 January 2018

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Postmortem studies in mood disorders indicate altered numbers of neurons and glial cells

21 January 2018

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Evaluation of the orthogonal projection on latent structure model limitations caused by chemical shift variability and improved visualization of biomarker changes in 1H NMR spectroscopic metabonomic studies.

21 January 2018

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Neurochemical alterations of the brain in bipolar disorder and their implications for pathophysiology: a systematic review of the in vivo proton magnetic resonance spectroscopy findings

21 January 2018

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Decreased anterior cingulate myo-inositol/creatine spectroscopy resonance with lithium treatment in children with bipolar disorder

21 January 2018

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Choline, myo-inositol and mood in bipolar disorder: a proton magnetic resonance spectroscopic imaging study of the anterior cingulate cortex.

21 January 2018

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Reduced NAA levels in the dorsolateral prefrontal cortex of young bipolar patients

21 January 2018

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A proton magnetic resonance spectroscopy investigation of the dorsolateral prefrontal cortex in acute mania

21 January 2018

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Brain metabolic alterations in medication-free patients with bipolar disorder

21 January 2018

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INHIBITION OF UPTAKE OF TRITIATED-NORADRENALINE IN THE INTACT RAT BRAIN BY IMIPRAMINE AND STRUCTURALLY RELATED COMPOUNDS.

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.MP.4002130

Lithium and bipolar mood disorder: the inositol-depletion hypothesis revisited

21 January 2018

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Chronic lithium and sodium valproate both decrease the concentration of myo-inositol and increase the concentration of inositol monophosphates in rat brain

21 January 2018

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Multinuclear NMR studies on the energy metabolism of glial and neuronal cells

21 January 2018

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Valproate decreases inositol biosynthesis

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.MP.4002130

Inhibition of the high affinity myo-inositol transport system: a common mechanism of action of antibipolar drugs?

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.MP.4002130

Mitochondrial dysfunction in bipolar disorder: from 31P-magnetic resonance spectroscopic findings to their molecular mechanisms.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4002130

Molecular evidence for mitochondrial dysfunction in bipolar disorder

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4002130

Altered expression of mitochondria-related genes in postmortem brains of patients with bipolar disorder or schizophrenia, as revealed by large-scale DNA microarray analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4002130

Decrease in creatine kinase messenger RNA expression in the hippocampus and dorsolateral prefrontal cortex in bipolar disorder

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4002130

Increases in cortical glutamate concentrations in transgenic amyotrophic lateral sclerosis mice are attenuated by creatine supplementation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4002130

Effects of chronic lithium administration on rat brain phosphatidylinositol cycle constituents, membrane phospholipids and amino acids

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4002130

Subgenual prefrontal cortex abnormalities in mood disorders.

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.MP.4002130

Abnormal FMRI brain activation in euthymic bipolar disorder patients during a counting Stroop interference task

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.MP.4002130

Anomalous prefrontal-subcortical activation in familial pediatric bipolar disorder: a functional magnetic resonance imaging investigation.

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.MP.4002130

Effects of mood and subtype on cerebral glucose metabolism in treatment-resistant bipolar disorder

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.MP.4002130

Frontal cortex and basal ganglia metabolic rates assessed by positron emission tomography with [18F]2-deoxyglucose in affective illness.

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.MP.4002130

13C magnetic resonance spectroscopy studies of alterations in glutamate neurotransmission

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4002130

Differential effects of acute and short-term lithium administration on dialysate glutamate and GABA levels in the frontal cortex of the conscious rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4002130

GABAB receptors are up-regulated by chronic treatment with lithium or carbamazepine. GABA hypothesis of affective disorders?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4002130

Interconversion of myo- and scyllo-inositol with simultaneous formation of neo-inositol by an NADP+ dependent epimerase from bovine brain

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.MP.4002130

Lactate as a pivotal element in neuron-glia metabolic cooperation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4002130

Excitotoxic preconditioning elicited by both glutamate and hypoxia and abolished by lactate transport inhibition in rat hippocampal slices

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4002130

Lactate reduces glutamate-induced neurotoxicity in rat cortex

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4002130

Do lithium and anticonvulsants target the brain arachidonic acid cascade in bipolar disorder?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4002130

Chronic lithium downregulates cyclooxygenase-2 activity and prostaglandin E(2) concentration in rat brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4002130

Magnetic resonance spectroscopy in AD.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4002130

MR spectroscopy in stroke

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4002130

1H MRS study of dorsolateral prefrontal cortex in healthy individuals before and after lithium administration

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4002130

Effects of chronic lithium and sodium valproate on concentrations of brain amino acids

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4002130

Cross-national epidemiology of major depression and bipolar disorder

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4002130

7 January 2021

https://api.crossref.org/works/10.1038%2FSJ.MP.4002130

1 reference

7 January 2021

The role of the extracellular signal-regulated kinase signaling pathway in mood modulation.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4002130

7 January 2021

Lithium-induced increase in human brain grey matter

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4002130

7 January 2021

Lithium increases N-acetyl-aspartate in the human brain: in vivo evidence in support of bcl-2's neurotrophic effects?

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4002130

7 January 2021

The stanley foundation brain collection and neuropathology consortium

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4002130

7 January 2021

High-resolution magic angle spinning 1H NMR spectroscopic studies on intact rat renal cortex and medulla

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4002130

7 January 2021

Nuclear magnetic resonance spectroscopy: a non-invasive probe of kidney metabolism and function

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4002130

7 January 2021

Osmoregulatory changes in myo-inositol content and Na+/myo-inositol cotransport in rat cortical astrocytes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4002130

7 January 2021

Phosphocreatine-dependent Glutamate Uptake by Synaptic Vesicles

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4002130

7 January 2021

A simulation study of brain compartments. Metabolism of glutamate and related substances in mouse brain

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4002130

7 January 2021

Effect of Lithium on Concentrations of Glutamate and GABA Levels in Amygdala and Hypothalamus of Rat

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4002130

7 January 2021

Brain gabaergic and dopaminergic systems following lithium treatment and withdrawal

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4002130

7 January 2021

Valproic acid down‐regulates the conversion of arachidonic acid to eicosanoids via cyclooxygenase‐1 and ‐2 in rat brain

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4002130

7 January 2021

In vitro proton and phosphorus NMR spectroscopic analysis of murine (C57Bl/6J) brain development

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4002130

7 January 2021

Identifiers

DOI

10.1038/SJ.MP.4002130

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25 December 2017

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25 December 2017