(Q36281844)

13 August 2017

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title

Mood stabilizers target cellular plasticity and resilience cascades: implications for the development of novel therapeutics (English)

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13 August 2017

Rosilla F Bachmann

1

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13 August 2017

Robert J Schloesser

series ordinal

2

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13 August 2017

Todd D Gould

series ordinal

3

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13 August 2017

Husseini K Manji

series ordinal

4

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13 August 2017

language of work or name

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1 October 2005

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13 August 2017

published in

Molecular Neurobiology

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13 August 2017

volume

32

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13 August 2017

issue

2

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13 August 2017

page(s)

173-202

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https://scigraph.springernature.com/pub.10.1385/mn:32:2:173

13 August 2017

exact match

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cites work

A preliminary investigation of a protein kinase C inhibitor in the treatment of acute mania

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12 December 2020

The role of the extracellular signal-regulated kinase signaling pathway in mood modulation.

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12 December 2020

Glycogen synthase kinase-3 and dorsoventral patterning in Xenopus embryos

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12 December 2020

Valproic acid defines a novel class of HDAC inhibitors inducing differentiation of transformed cells

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12 December 2020

Glycogen synthase kinase-3: a target for novel bipolar disorder treatments.

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12 December 2020

GSK3beta signalling: casting a wide net in Alzheimer's disease

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12 December 2020

Postinsult treatment with lithium reduces brain damage and facilitates neurological recovery in a rat ischemia/reperfusion model

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12 December 2020

GSK-3alpha regulates production of Alzheimer's disease amyloid-beta peptides

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12 December 2020

The effects of lithium ion and other agents on the activity of myo-inositol-1-phosphatase from bovine brain

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12 December 2020

Cell signaling by receptor tyrosine kinases

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12 December 2020

Abnormalities in protein kinase C signaling and the pathophysiology of bipolar disorder

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12 December 2020

Definition of a metal-dependent/Li(+)-inhibited phosphomonoesterase protein family based upon a conserved three-dimensional core structure

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12 December 2020

Lithium-induced respecification of pattern in Xenopus laevis embryos

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12 December 2020

Lithium activates the serine/threonine kinase Akt-1 and suppresses glutamate-induced inhibition of Akt-1 activity in neurons

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12 December 2020

Lithium inhibition of phosphofructokinase

1 reference

12 December 2020

Lithium increases N-acetyl-aspartate in the human brain: in vivo evidence in support of bcl-2's neurotrophic effects?

1 reference

12 December 2020

The mood-stabilizing agent valproate inhibits the activity of glycogen synthase kinase-3.

1 reference

12 December 2020

Judging a protein by more than its name: GSK-3.

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12 December 2020

Inhibition of protein kinase C--do we, can we, and should we?

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12 December 2020

Valproate administration to mice increases histone acetylation and 5-lipoxygenase content in the hippocampus

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12 December 2020

Partial lithium-associated protection against apoptosis induced by C2-ceramide in cerebellar granule neurons.

1 reference

12 December 2020

Different localization of tau protein kinase I/glycogen synthase kinase-3 beta from glycogen synthase kinase-3 alpha in cerebellum mitochondria

1 reference

12 December 2020

Stress-induced changes in brain-derived neurotrophic factor expression are attenuated in aged Fischer 344/N rats.

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12 December 2020

Effects of the anticonvulsant sodium valproate on gamma-aminobutyrate and aldehyde metabolism in ox brain

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12 December 2020

Alternative projections of mortality and disability by cause 1990-2020: Global Burden of Disease Study

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12 December 2020

Organization of the stress system and its dysregulation in melancholic and atypical depression: high vs low CRH/NE states

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12 December 2020

The renaissance of GSK3

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12 December 2020

Increased brain myo-inositol 1-phosphate in lithium-treated rats.

1 reference

12 December 2020

Enhanced dopamine release and phosphorylation of synapsin I and neuromodulin in striatal synaptosomes after repeated amphetamine.

1 reference

12 December 2020

Neurotrophins and neuronal differentiation in the central nervous system.

1 reference

12 December 2020

Myristoylated alanine-rich C kinase substrate (MARCKS): a molecular target for the therapeutic action of mood stabilizers in the brain?

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12 December 2020

Ruboxistaurin (Eli Lilly).

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12 December 2020

Enhancement of hippocampal neurogenesis by lithium

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12 December 2020

Stress and hippocampal plasticity

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12 December 2020

Signaling networks in the pathophysiology and treatment of mood disorders

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12 December 2020

Molecular machines integrate coincident synaptic signals

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12 December 2020

Enhancing neuronal plasticity and cellular resilience to develop novel, improved therapeutics for Difficult-to-Treat depression

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12 December 2020

Search for a common mechanism of mood stabilizers.

1 reference

12 December 2020

Chronic lithium administration alters a prominent PKC substrate in rat hippocampus

1 reference

12 December 2020

Downregulation of BDNF mRNA in the hippocampal dentate gyrus after re-exposure to cues previously associated with footshock.

1 reference

12 December 2020

Lithium enhances long‐term potentiation independently of hippocampal neurogenesis in the rat dentate gyrus

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12 December 2020

Complexity in biological signaling systems

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12 December 2020

The mood-stabilizing agents lithium and valproate robustly increase the levels of the neuroprotective protein bcl-2 in the CNS

1 reference

12 December 2020

Glucocorticoids and hippocampal atrophy in neuropsychiatric disorders

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12 December 2020

Chronic lithium enhances hippocampal long-term potentiation, but not neurogenesis, in the aged rat dentate gyrus

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12 December 2020

Bone mineral density in women with depression.

1 reference

12 December 2020

Lithium antagonizes dopamine-dependent behaviors mediated by an AKT/glycogen synthase kinase 3 signaling cascade

1 reference

12 December 2020

Relapse and impairment in bipolar disorder

1 reference

12 December 2020

Altered platelet protein kinase C activity in bipolar affective disorder, manic episode

1 reference

12 December 2020

Functional impairment and cognition in bipolar disorder

1 reference

12 December 2020

Neurobiology of depression: focus on dopamine.

1 reference

12 December 2020

Regulation of Akt and glycogen synthase kinase-3 beta phosphorylation by sodium valproate and lithium

1 reference

12 December 2020

Cell proliferation in adult hippocampus is decreased by inescapable stress: reversal by fluoxetine treatment

1 reference

12 December 2020

A nonsteroidal glucocorticoid receptor antagonist

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12 December 2020

Neuroprotective effects of lithium in cultured cells and animal models of diseases.

1 reference

12 December 2020

Neuroimaging and neuropathological studies of depression: implications for the cognitive-emotional features of mood disorders

1 reference

12 December 2020

In vitro and in vivo inhibition of inositol monophosphatase by the bisphosphonate L-690,330.

1 reference

12 December 2020

Synaptic activity-dependent modulation of mitochondrial gene expression in the rat hippocampus

1 reference

12 December 2020

Regulation of tau phosphorylation and protection against beta-amyloid-induced neurodegeneration by lithium. Possible implications for Alzheimer's disease

1 reference

12 December 2020

Ziskind-Somerfeld Research Award. Protein kinase C signaling in the brain: molecular transduction of mood stabilization in the treatment of manic-depressive illness

1 reference

12 December 2020

Neuroplasticity and cellular resilience in mood disorders

1 reference

12 December 2020

Lithium at 50: have the neuroprotective effects of this unique cation been overlooked?

1 reference

12 December 2020

Mitochondrial dysfunction in bipolar disorder

1 reference

12 December 2020

The antidepressant and antiinflammatory effects of rolipram in the central nervous system

1 reference

12 December 2020

Mitochondrial potassium channels and uncoupling proteins in synaptic plasticity and neuronal cell death

1 reference

12 December 2020

The Wnt signaling pathway in bipolar disorder

1 reference

12 December 2020

Li+ protects nerve cells against destabilization of Ca2+ homeostasis and delayed death caused by removal of external Na+

1 reference

12 December 2020

Chronic lithium treatment increases the expression of brain-derived neurotrophic factor in the rat brain

1 reference

12 December 2020

Neuroprotective effects of chronic lithium on focal cerebral ischemia in rats

1 reference

12 December 2020

Glycogen synthase kinase-3beta phosphorylates Bax and promotes its mitochondrial localization during neuronal apoptosis.

1 reference

12 December 2020

Selective Inhibition of the Expression of Signal Transduction Proteins by Lithium in Nerve Growth Factor‐Differentiated PC12 Cells

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12 December 2020

Rapid antidepressive-like activity of specific glycogen synthase kinase-3 inhibitor and its effect on beta-catenin in mouse hippocampus.

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12 December 2020

Bcl-2 potentiates the maximal calcium uptake capacity of neural cell mitochondria

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12 December 2020

Hypoxia death stimulus induces translocation of p53 protein to mitochondria. Detection by immunofluorescence on whole cells

1 reference

12 December 2020

Lithium protection against glutamate excitotoxicity in rat cerebral cortical neurons: involvement of NMDA receptor inhibition possibly by decreasing NR2B tyrosine phosphorylation.

1 reference

12 December 2020

Neural and developmental actions of lithium: a unifying hypothesis

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12 December 2020

Lithium induces brain-derived neurotrophic factor and activates TrkB in rodent cortical neurons: an essential step for neuroprotection against glutamate excitotoxicity.

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12 December 2020

A molecular mechanism for the effect of lithium on development

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12 December 2020

Death signal-induced localization of p53 protein to mitochondria. A potential role in apoptotic signaling

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12 December 2020

Modulation of CNS signal transduction pathways and gene expression by mood-stabilizing agents: therapeutic implications

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12 December 2020

The codon 72 polymorphic variants of p53 have markedly different apoptotic potential

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12 December 2020

Adult brain neurogenesis and depression

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12 December 2020

Mechanism of inositol monophosphatase, the putative target of lithium therapy

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12 December 2020

Emerging experimental therapeutics for bipolar disorder: insights from the molecular and cellular actions of current mood stabilizers

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12 December 2020

Regulation and localization of tyrosine216 phosphorylation of glycogen synthase kinase-3beta in cellular and animal models of neuronal degeneration

1 reference

12 December 2020

Different expression of glycogen synthase kinase-3beta between young and old rat brains after transient middle cerebral artery occlusion.

1 reference

12 December 2020

Proceedings: gamma-Aminobutyric acid metabolism and the anticonvulsant action of ethanolamine-o-sulphate and di-n-propylacetate

1 reference

12 December 2020

Mammalian neural stem cells

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12 December 2020

Mood stabilizers, glycogen synthase kinase-3beta and cell survival

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12 December 2020

The role of glycogen synthase kinase-3 in insulin resistance and type 2 diabetes

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12 December 2020

Sodium valproate down-regulates the myristoylated alanine-rich C kinase substrate (MARCKS) in immortalized hippocampal cells: a property of protein kinase C-mediated mood stabilizers.

1 reference

12 December 2020

Is phosphodiesterase inhibition a new mechanism of antidepressant action? A double blind double-dummy study between rolipram and desipramine in hospitalized major and/or endogenous depressives

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12 December 2020

Specificity and mechanism of action of some commonly used protein kinase inhibitors

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12 December 2020

Enhanced protein kinase C activity and translocation in bipolar affective disorder brains.

1 reference

12 December 2020

A review of psychosocial outcome in patients with bipolar disorder

1 reference

12 December 2020

Volumetric MRI studies of mood disorders: do they distinguish unipolar and bipolar disorder?

1 reference

12 December 2020

Preclinical models: status of basic research in depression

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12 December 2020

Lithium inhibits glycogen synthase kinase-3 by competition for magnesium.

1 reference

12 December 2020

Antidepressants and neuroplasticity

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12 December 2020

Chronic treatment with lithium, but not sodium valproate, increases cortical N-acetyl-aspartate concentrations in euthymic bipolar patients

1 reference

12 December 2020

Modulators of the glutamatergic system: implications for the development of improved therapeutics in mood disorders

1 reference

12 December 2020

Lithium inhibits glycogen synthase kinase-3 activity and mimics wingless signalling in intact cells

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12 December 2020

Lithium suppresses excitotoxicity-induced striatal lesions in a rat model of Huntington's disease

1 reference

12 December 2020

Neuroimaging Abnormalities in the Amygdala in Mood Disorders

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12 December 2020

Temporal dissociation between lithium-induced changes in frontal lobe myo-inositol and clinical response in manic-depressive illness

1 reference

12 December 2020

Glycogen synthase kinase-3beta, mood stabilizers, and neuroprotection

1 reference

12 December 2020

Repeated restraint stress suppresses neurogenesis and induces biphasic PSA-NCAM expression in the adult rat dentate gyrus

1 reference

12 December 2020

Volumetric brain imaging findings in mood disorders

1 reference

12 December 2020

Regulation of adult neurogenesis by antidepressant treatment

1 reference

12 December 2020

The mood stabilizer valproic acid activates mitogen-activated protein kinases and promotes neurite growth

1 reference

12 December 2020

Two-year syndromal and functional recovery in 219 cases of first-episode major affective disorder with psychotic features.

1 reference

12 December 2020

Neuroimaging studies of mood disorder effects on the brain

1 reference

12 December 2020

Regulation of signal transduction pathways by mood-stabilizing agents: implications for the delayed onset of therapeutic efficacy

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12 December 2020

Lithium amplifies agonist-dependent phosphatidylinositol responses in brain and salivary glands

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12 December 2020

Effects of anticonvulsant drugs on the cerebral enzymes metabolizing GABA.

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12 December 2020

Prodromal and residual symptoms in bipolar I disorder.

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12 December 2020

Emergent properties of networks of biological signaling pathways

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12 December 2020

Requirement of hippocampal neurogenesis for the behavioral effects of antidepressants

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12 December 2020

Specific and direct binding of protein kinase C to an immobilized tamoxifen analogue

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12 December 2020

Regulation of neurogenesis by growth factors and neurotransmitters

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12 December 2020

The anatomy of mood disorders--review of structural neuroimaging studies

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12 December 2020

Histone deacetylase is a direct target of valproic acid, a potent anticonvulsant, mood stabilizer, and teratogen

1 reference

12 December 2020

Lithium induces apoptosis in immature cerebellar granule cells but promotes survival of mature neurons

1 reference

12 December 2020

Depression and Diabetes

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12 December 2020

Molecular basis of lithium action: integration of lithium-responsive signaling and gene expression networks

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12 December 2020

Modulation of protein kinase C isozymes and substrates by lithium: the role of myo-inositol

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12 December 2020

The relationship of depression to cardiovascular disease: epidemiology, biology, and treatment

1 reference

12 December 2020

Insulin mimetic action of synthetic phosphorylated peptide inhibitors of glycogen synthase kinase-3.

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12 December 2020

Chronic lithium-induced down-regulation of MARCKS in immortalized hippocampal cells: potentiation by muscarinic receptor activation

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12 December 2020

Prevalence and clinical correlates of residual depressive symptoms in bipolar II disorder

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12 December 2020

Lithium-induced increase in human brain grey matter

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12 December 2020

Increased gray matter volume in lithium-treated bipolar disorder patients

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12 December 2020

New approaches to modeling bipolar disorder

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12 December 2020

Phosphorylation of glycogen synthase kinase-3beta during preconditioning through a phosphatidylinositol-3-kinase--dependent pathway is cardioprotective

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12 December 2020

Effects of stress on neurotrophic factor expression in the rat brain.

1 reference

12 December 2020

Valproate regulates GSK-3-mediated axonal remodeling and synapsin I clustering in developing neurons

1 reference

12 December 2020

Chronic sodium valproate selectively decreases protein kinase C alpha and epsilon in vitro.

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12 December 2020

Lithium decreases membrane-associated protein kinase C in hippocampus: selectivity for the alpha isozyme

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12 December 2020

Reduced glial cell density and neuronal size in the anterior cingulate cortex in major depressive disorder.

1 reference

12 December 2020

Reduced Brain Inositol in Lithium-treated Rats

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12 December 2020

Chronic lithium treatment robustly protects neurons in the central nervous system against excitotoxicity by inhibiting N-methyl-D-aspartate receptor-mediated calcium influx

1 reference

12 December 2020

Lithium protects rat cerebellar granule cells against apoptosis induced by anticonvulsants, phenytoin and carbamazepine.

1 reference

12 December 2020

The emerging differential roles of GABAergic and antiglutamatergic agents in bipolar disorders

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12 December 2020

Histone deacetylases and cancer: causes and therapies

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12 December 2020

Antidepressant-like effects of CP-154,526, a selective CRF1 receptor antagonist.

1 reference

12 December 2020

Brain-derived neurotrophic factor produces antidepressant effects in behavioral models of depression.

1 reference

12 December 2020

Long term lithium treatment suppresses p53 and Bax expression but increases Bcl-2 expression. A prominent role in neuroprotection against excitotoxicity

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12 December 2020

Cell pathology in bipolar disorder

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12 December 2020

Comparison of fluorescence, (31)P NMR, and (7)Li NMR spectroscopic methods for investigating Li(+)/Mg(2+) competition for biomolecules

1 reference

12 December 2020

Protein kinase C overactivity impairs prefrontal cortical regulation of working memory.

1 reference

12 December 2020

AR-A014418, a selective GSK-3 inhibitor, produces antidepressant-like effects in the forced swim test

1 reference

12 December 2020

Inhibition of protein kinase C mediated signal transduction by tamoxifen. Importance for antitumour activity.

1 reference

12 December 2020

Valproic acid reduces brain damage induced by transient focal cerebral ischemia in rats: potential roles of histone deacetylase inhibition and heat shock protein induction

1 reference

12 December 2020

Inhibition of glycogen synthase kinase-3beta by bivalent zinc ions: insight into the insulin-mimetic action of zinc

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12 December 2020

Psychoneuroendocrinology of depression. Hypothalamic-pituitary-adrenal axis

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12 December 2020

Lithium protects cultured neurons against beta-amyloid-induced neurodegeneration

1 reference

12 December 2020

Structure of inositol monophosphatase, the putative target of lithium therapy

1 reference

12 December 2020

Mania in association with hydrocortisone replacement for Addison's disease

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12 December 2020

Glycogen synthase kinase 3 (GSK-3) inhibitors as new promising drugs for diabetes, neurodegeneration, cancer, and inflammation

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12 December 2020

Inositol monophosphatase inhibitors--lithium mimetics?

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12 December 2020

In vivo regulation of glycogen synthase kinase-3beta (GSK3beta) by serotonergic activity in mouse brain

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12 December 2020

Enhanced phosphorylation of the postsynaptic protein kinase C substrate RC3/neurogranin during long-term potentiation.

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12 December 2020

GSK3 takes centre stage more than 20 years after its discovery

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12 December 2020

Chronic antidepressant treatment increases neurogenesis in adult rat hippocampus

1 reference

12 December 2020

Neurotrophins and synaptic plasticity

1 reference

12 December 2020

Increased hippocampal BDNF immunoreactivity in subjects treated with antidepressant medication

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12 December 2020

Lithium-mediated phosphorylation of glycogen synthase kinase-3beta involves PI3 kinase-dependent activation of protein kinase C-alpha

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12 December 2020

The potential role of PKC beta in diabetic retinopathy and macular edema

1 reference

12 December 2020

The pharmacology of CP-154,526, a non-peptide antagonist of the CRH1 receptor: a review

1 reference

12 December 2020

Results of a phase II study of the antidepressant effect of rolipram

1 reference

12 December 2020

Depression, antidepressants, and the shrinking hippocampus

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12 December 2020

An investigation of the neuroprotective effect of lithium in organotypic slice cultures of rat hippocampus exposed to oxygen and glucose deprivation

1 reference

12 December 2020

Glucocorticoid Receptor Antagonism by Cyproterone Acetate and RU486

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12 December 2020

Lithium stimulates progenitor proliferation in cultured brain neurons.

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12 December 2020

Mitochondria and Ca(2+)in cell physiology and pathophysiology

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12 December 2020

1 reference

12 December 2020

Functional anatomical abnormalities in limbic and prefrontal cortical structures in major depression

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12 December 2020

Amphetamine increases the phosphorylation of neuromodulin and synapsin I in rat striatal synaptosomes.

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12 December 2020

Finding the Intracellular Signaling Pathways Affected by Mood Disorder Treatments

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12 December 2020

Regulation of BDNF and trkB mRNA in rat brain by chronic electroconvulsive seizure and antidepressant drug treatments.

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12 December 2020

Antidepressants alter cell proliferation in the adult brain in vivo and in neural cultures in vitro.

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12 December 2020

Mechanisms of action of valproate: a commentatory

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12 December 2020

Lithium and valproic acid: parallels and contrasts in diverse signaling contexts

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12 December 2020

Support of retinal ganglion cell survival and axon regeneration by lithium through a Bcl-2-dependent mechanism

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12 December 2020

Regulation of hippocampal neurogenesis in adulthood.

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12 December 2020

Molecular targets of lithium action

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12 December 2020

The influence of hormones and pharmaceutical agents on DHEA and DHEA-S concentrations: a review of clinical studies

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12 December 2020

Impairments of neuroplasticity and cellular resilience in severe mood disorders: implications for the development of novel therapeutics

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12 December 2020

Stress and depression: possible links to neuron death in the hippocampus

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12 December 2020

An epigenetic mouse model for molecular and behavioral neuropathologies related to schizophrenia vulnerability

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12 December 2020

Trk receptors: mediators of neurotrophin action

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12 December 2020

Biosynthesis of myo-inositol in rat mammary gland. Isolation and properties of the enzymes.

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12 December 2020

PKC, MAP kinases and the bcl-2 family of proteins as long-term targets for mood stabilizers

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12 December 2020

CREB DNA binding activity is inhibited by glycogen synthase kinase-3 beta and facilitated by lithium

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12 December 2020

Valproic acid, a mood stabilizer and anticonvulsant, protects rat cerebral cortical neurons from spontaneous cell death: a role of histone deacetylase inhibition

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12 December 2020

Potential new medical therapies for diabetic retinopathy: protein kinase C inhibitors

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12 December 2020

Caspase-3 activation induced by inhibition of mitochondrial complex I is facilitated by glycogen synthase kinase-3beta and attenuated by lithium

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12 December 2020

First non-ATP competitive glycogen synthase kinase 3 beta (GSK-3beta) inhibitors: thiadiazolidinones (TDZD) as potential drugs for the treatment of Alzheimer's disease

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12 December 2020

A common mechanism of action for three mood-stabilizing drugs

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12 December 2020

Endophenotypes in bipolar disorder

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12 December 2020

Effects of L-690,488, a prodrug of the bisphosphonate inositol monophosphatase inhibitor L-690,330, on phosphatidylinositol cycle markers.

1 reference

12 December 2020

Protein kinase C and dopamine transport--2. Effects of amphetamine in vitro

1 reference

12 December 2020

G protein-mediated signal transduction as a target of antidepressant and antibipolar drug action: evidence from model systems

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12 December 2020

Glycogen Synthase Kinase-3β (GSK3β) Binds to and Promotes the Actions of p53

1 reference

12 December 2020

Neuroimaging in bipolar disorder: what have we learned?

1 reference

12 December 2020

The cellular neurobiology of depression

1 reference

12 December 2020

Inhibitory phosphorylation of glycogen synthase kinase-3 (GSK-3) in response to lithium. Evidence for autoregulation of GSK-3.

1 reference

12 December 2020

Phosphorylation of neuromodulin in rat striatum after acute and repeated, intermittent amphetamine

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12 December 2020

Manipulation of neural precursors in situ: induction of neurogenesis in the neocortex of adult mice

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12 December 2020

Mood stabilizer valproate promotes ERK pathway-dependent cortical neuronal growth and neurogenesis.

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12 December 2020

G proteins: implications for psychiatry

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12 December 2020

Phosphoglucomutase is an in vivo lithium target in yeast

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12 December 2020

Rapid accumulation of Akt in mitochondria following phosphatidylinositol 3-kinase activation

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12 December 2020

Neurotrophins as synaptic modulators

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12 December 2020

Lithium inhibits amyloid secretion in COS7 cells transfected with amyloid precursor protein C100.

1 reference

12 December 2020

Neurotrophins and cortical development

1 reference

12 December 2020

In vivo evidence in the brain for lithium inhibition of glycogen synthase kinase-3.

1 reference

12 December 2020

Rolipram in major depressive disorder: results of a double-blind comparative study with imipramine

1 reference

12 December 2020

Valproate inhibits oxidative damage to lipid and protein in primary cultured rat cerebrocortical cells

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12 December 2020

Long-term lithium treatment prevents neurotoxic effects of beta-bungarotoxin in primary cultured neurons.

1 reference

12 December 2020

THE EFFECTS OF STRESSFUL LIFE EVENTS ON DEPRESSION

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12 December 2020

Immobilization stress reduced the expression of neurotrophins and their receptors in the rat brain.

1 reference

12 December 2020

Adult brain neurogenesis and psychiatry: a novel theory of depression

1 reference

12 December 2020

Di-n-propylacetate and GABA degradation. Preferential inhibition of succinic semialdehyde dehydrogenase and indirect inhibition of GABA-transaminase

1 reference

12 December 2020

Glycogen synthase kinase-3beta haploinsufficiency mimics the behavioral and molecular effects of lithium

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12 December 2020

Identifiers

DOI

10.1385/MN:32:2:173

1 reference

Dimensions Publication ID

13 August 2017

1016649818

0 references

1 reference