(Q46771769)

25 December 2017

title

In human endothelial cells rapamycin causes mTORC2 inhibition and impairs cell viability and function (English)

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25 December 2017

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25 December 2017

Roberto Sala

3

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25 December 2017

Ovidio Bussolati

11

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25 December 2017

Ellen I Closs

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Ellen I Closs

9

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Elena Tremoli

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Elena Tremoli

6

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Alessandro Parolari

5

object named as

Alessandro Parolari

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25 December 2017

author name string

Rossana Visigalli

2

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25 December 2017

Gian C Gazzola

4

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25 December 2017

Sabrina Bonomini

7

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25 December 2017

Alexandra Simon

8

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25 December 2017

Valeria Dall'Asta

10

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25 December 2017

publication date

4 February 2008

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25 December 2017

published in

Cardiovascular Research

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25 December 2017

volume

78

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25 December 2017

issue

3

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25 December 2017

page(s)

563-571

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25 December 2017

Rapamycin analogs for stent-based local drug delivery. Everolimus- and tacrolimus-eluting stents

cites work

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVN024

Drug-eluting stents: sirolimus and paclitaxel differentially affect cultured cells and injured arteries

21 January 2018

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A randomized comparison of a sirolimus-eluting stent with a standard stent for coronary revascularization

21 January 2018

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TOR signaling in growth and metabolism

21 January 2018

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https://api.crossref.org/works/10.1093%2FCVR%2FCVN024

Drug-eluting stent thrombosis: results from a pooled analysis including 10 randomized studies

21 January 2018

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https://api.crossref.org/works/10.1093%2FCVR%2FCVN024

Indication of long-term endothelial dysfunction after sirolimus-eluting stent implantation

21 January 2018

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https://api.crossref.org/works/10.1093%2FCVR%2FCVN024

Impaired endothelial vasomotor function after sirolimus-eluting stent implantation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVN024

Rictor, a novel binding partner of mTOR, defines a rapamycin-insensitive and raptor-independent pathway that regulates the cytoskeleton

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVN024

21 January 2018

The two TORCs and Akt.

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVN024

Cyclosporine and tacrolimus for the treatment of rheumatoid arthritis

21 January 2018

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https://api.crossref.org/works/10.1093%2FCVR%2FCVN024

Expression of tumour necrosis factor alpha and accumulation of fibronectin in coronary artery restenotic lesions retrieved by atherectomy

21 January 2018

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https://api.crossref.org/works/10.1093%2FCVR%2FCVN024

Endothelial dysfunction and inflammation after percutaneous coronary intervention.

21 January 2018

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https://api.crossref.org/works/10.1093%2FCVR%2FCVN024

Rapamycin, but not FK-506, increases endothelial tissue factor expression: implications for drug-eluting stent design

21 January 2018

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Investigation of the Alamar Blue (resazurin) fluorescent dye for the assessment of mammalian cell cytotoxicity.

21 January 2018

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https://api.crossref.org/works/10.1093%2FCVR%2FCVN024

Role of neutral amino acid transport and protein breakdown for substrate supply of nitric oxide synthase in human endothelial cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVN024

PKC-dependent stimulation of EAAT3 glutamate transporter does not require the integrity of actin cytoskeleton

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVN024

Activation of endothelial-leukocyte adhesion molecule 1 (ELAM-1) gene transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVN024

Tumor necrosis factor-alpha inhibits endothelial nitric-oxide synthase gene promoter activity in bovine aortic endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVN024

Prolonged rapamycin treatment inhibits mTORC2 assembly and Akt/PKB

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVN024

Stress and mTORture signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVN024

Upstream of the mammalian target of rapamycin: do all roads pass through mTOR?

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVN024

Mammalian TOR complex 2 controls the actin cytoskeleton and is rapamycin insensitive

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVN024

A phosphatidylinositol 3-kinase/Akt pathway, activated by tumor necrosis factor or interleukin-1, inhibits apoptosis but does not activate NFkappaB in human endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVN024

Loss of Akt1 leads to severe atherosclerosis and occlusive coronary artery disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVN024

The effects of mTOR-Akt interactions on anti-apoptotic signaling in vascular endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVN024

Regulation of endothelium-derived nitric oxide production by the protein kinase Akt

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVN024

Activation of endothelial nitric-oxide synthase by tumor necrosis factor-alpha: a novel pathway involving sequential activation of neutral sphingomyelinase, phosphatidylinositol-3' kinase, and Akt.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVN024

Endothelial nitric oxide synthase: the Cinderella of inflammation?

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVN024

Pathology of drug-eluting stents in humans: delayed healing and late thrombotic risk.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVN024

Pathological angiogenesis is induced by sustained Akt signaling and inhibited by rapamycin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVN024

Rapamycin stimulates arginine influx through CAT2 transporters in human endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVN024

21 January 2018

Identifiers

DOI

10.1093/CVR/CVN024

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25 December 2017

PubMed ID

18250144

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25 December 2017