(Q46774153)

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Synthesis and evaluation of 9,9-dimethylxanthene tricyclics against trypanothione reductase, Trypanosoma brucei, Trypanosoma cruzi and Leishmania donovani

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

25 December 2017

http://europepmc.org/abstract/MED/10866368

Synthesis and evaluation of 9,9-dimethylxanthene tricyclics against trypanothione reductase, Trypanosoma brucei, Trypanosoma cruzi and Leishmania donovani (English)

1 reference

Europe PubMed Central

PubMed publication ID

25 December 2017

http://europepmc.org/abstract/MED/10866368

Trypanosoma cruzi

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Trypanosoma brucei

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Leishmania donovani

object named as

Leishmania donovani

1 reference

based on heuristic

inferred from title

object named as

Fairlamb AH

5

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author name string

Chibale K

1

1 reference

Europe PubMed Central

PubMed publication ID

25 December 2017

http://europepmc.org/abstract/MED/10866368

Visser M

2

1 reference

Europe PubMed Central

PubMed publication ID

25 December 2017

http://europepmc.org/abstract/MED/10866368

Yardley V

3

1 reference

Europe PubMed Central

PubMed publication ID

25 December 2017

http://europepmc.org/abstract/MED/10866368

Croft SL

4

1 reference

Europe PubMed Central

PubMed publication ID

25 December 2017

http://europepmc.org/abstract/MED/10866368

language of work or name

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publication date

1 June 2000

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Europe PubMed Central

PubMed publication ID

25 December 2017

http://europepmc.org/abstract/MED/10866368

Bioorganic & Medicinal Chemistry Letters

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Europe PubMed Central

PubMed publication ID

25 December 2017

http://europepmc.org/abstract/MED/10866368

10

1 reference

Europe PubMed Central

PubMed publication ID

25 December 2017

http://europepmc.org/abstract/MED/10866368

11

1 reference

Europe PubMed Central

PubMed publication ID

25 December 2017

http://europepmc.org/abstract/MED/10866368

1147-1150

1 reference

Europe PubMed Central

PubMed publication ID

25 December 2017

http://europepmc.org/abstract/MED/10866368

Rationally designed selective inhibitors of trypanothione reductase. Phenothiazines and related tricyclics as lead structures

1 reference

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based on heuristic

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Phenothiazine inhibitors of trypanothione reductase as potential antitrypanosomal and antileishmanial drugs

1 reference

https://api.crossref.org/works/10.1016%2FS0960-894X%2800%2900154-2

7 January 2021

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Trypanothione: a novel bis(glutathionyl)spermidine cofactor for glutathione reductase in trypanosomatids

1 reference

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7 January 2021

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Crystal structure of the Trypanosoma cruzi trypanothione reductase.mepacrine complex

1 reference

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7 January 2021

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Crystal structure of Trypanosoma cruzi trypanothione reductase in complex with trypanothione, and the structure-based discovery of new natural product inhibitors

1 reference

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7 January 2021

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Charge is the major discriminating factor for glutathione reductase versus trypanothione reductase inhibitors

1 reference

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7 January 2021

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Site-directed mutagenesis of the redox-active cysteines of Trypanosoma cruzi trypanothione reductase.

1 reference

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based on heuristic

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An in-vitro system for determining the activity of compounds against the intracellular amastigote form of Leishmania donovani

1 reference

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7 January 2021

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inferred from DOI database lookup

A colorimetric assay for trypanosome viability and metabolic function

1 reference

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based on heuristic

inferred from DOI database lookup

Antileishmanial actions of tricyclic neuroleptics appear to lack structural specificity

1 reference

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Trypanosoma cruzi: possible control of parasite transmission by blood transfusion using amphiphilic cationic drugs

1 reference

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inferred from DOI database lookup

Identifiers

10.1016/S0960-894X(00)00154-2

1 reference

Europe PubMed Central

PubMed publication ID

25 December 2017

http://europepmc.org/abstract/MED/10866368

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

25 December 2017

http://europepmc.org/abstract/MED/10866368

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