(Q46777308)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25653221%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

title

Effect of selective LRRK2 kinase inhibition on nonhuman primate lung (English)

1 reference

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29 February 2020

27

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29 February 2020

19

Merone Roose-Girma

1 reference

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29 February 2020

author name string

Reina N Fuji

1

1 reference

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29 February 2020

Michael Flagella

2

1 reference

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29 February 2020

Miriam Baca

3

1 reference

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29 February 2020

Marco A S Baptista

4

1 reference

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29 February 2020

Jens Brodbeck

5

1 reference

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29 February 2020

Bryan K Chan

6

1 reference

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29 February 2020

Brian K Fiske

7

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29 February 2020

Lee Honigberg

8

1 reference

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29 February 2020

Adrian M Jubb

9

1 reference

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29 February 2020

Paula Katavolos

10

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29 February 2020

Donna W Lee

11

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29 February 2020

Sock-Cheng Lewin-Koh

12

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29 February 2020

Tori Lin

13

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29 February 2020

Xingrong Liu

14

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29 February 2020

Shannon Liu

15

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29 February 2020

Joseph P Lyssikatos

16

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29 February 2020

Jennifer O'Mahony

17

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29 February 2020

Mike Reichelt

18

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29 February 2020

Zejuan Sheng

20

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29 February 2020

Todd Sherer

21

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29 February 2020

Ashley Smith

22

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29 February 2020

Margaret Solon

23

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29 February 2020

Zachary K Sweeney

24

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29 February 2020

Jacqueline Tarrant

25

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29 February 2020

Alison Urkowitz

26

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29 February 2020

Murat Yaylaoglu

28

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29 February 2020

Shuo Zhang

29

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29 February 2020

Haitao Zhu

30

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29 February 2020

Anthony A Estrada

31

1 reference

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29 February 2020

Ryan J Watts

32

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29 February 2020

language of work or name

English

0 references

publication date

1 February 2015

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25653221%20AND%20SRC:MED&resulttype=core&format=json

Science Translational Medicine

29 February 2020

published in

1 reference

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29 February 2020

volume

7

1 reference

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29 February 2020

issue

273

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29 February 2020

page(s)

273ra15

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Mutations in LRRK2 cause autosomal-dominant parkinsonism with pleomorphic pathology

29 February 2020

cites work

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAA3634

Cloning of the gene containing mutations that cause PARK8-linked Parkinson's disease

21 January 2018

1 reference

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LRRK2 low-penetrance mutations (Gly2019Ser) and risk alleles (Gly2385Arg)-linking familial and sporadic Parkinson's disease

21 January 2018

1 reference

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Phenotype, genotype, and worldwide genetic penetrance of LRRK2-associated Parkinson's disease: a case-control study

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAA3634

Identification of a novel LRRK2 mutation linked to autosomal dominant parkinsonism: evidence of a common founder across European populations

21 January 2018

1 reference

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Update on the functional biology of Lrrk2.

21 January 2018

1 reference

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Parkinson's disease-associated mutations in leucine-rich repeat kinase 2 augment kinase activity

21 January 2018

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LRRK2 and Parkinson disease

21 January 2018

1 reference

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The role of leucine-rich repeat kinase 2 (LRRK2) in Parkinson's disease

21 January 2018

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Recent advances in the genetics of Parkinson's disease

21 January 2018

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Interplay of LRRK2 with chaperone-mediated autophagy

21 January 2018

1 reference

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A direct interaction between leucine-rich repeat kinase 2 and specific β-tubulin isoforms regulates tubulin acetylation

21 January 2018

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Kinase activity is required for the toxic effects of mutant LRRK2/dardarin

21 January 2018

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The Parkinson disease causing LRRK2 mutation I2020T is associated with increased kinase activity

21 January 2018

1 reference

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Ser1292 autophosphorylation is an indicator of LRRK2 kinase activity and contributes to the cellular effects of PD mutations.

21 January 2018

1 reference

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Discovery of highly potent, selective, and brain-penetrable leucine-rich repeat kinase 2 (LRRK2) small molecule inhibitors

21 January 2018

1 reference

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Discovery of highly potent, selective, and brain-penetrant aminopyrazole leucine-rich repeat kinase 2 (LRRK2) small molecule inhibitors

21 January 2018

1 reference

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LRRK2 protein levels are determined by kinase function and are crucial for kidney and lung homeostasis in mice

21 January 2018

1 reference

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Effect of lysosomal storage on bis(monoacylglycero)phosphate.

21 January 2018

1 reference

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Bis(monoacylglycerol)phosphate as a non-invasive biomarker to monitor the onset and time-course of phospholipidosis with drug-induced toxicities

21 January 2018

1 reference

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Comparison of urinary and serum levels of di-22:6-bis(monoacylglycerol)phosphate as noninvasive biomarkers of phospholipidosis in rats

21 January 2018

1 reference

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Di-22:6-bis(monoacylglycerol)phosphate: A clinical biomarker of drug-induced phospholipidosis for drug development and safety assessment

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAA3634

LRRK2 expression linked to dopamine-innervated areas

21 January 2018

1 reference

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Dynamic and redundant regulation of LRRK2 and LRRK1 expression

21 January 2018

1 reference

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Loss of leucine-rich repeat kinase 2 causes impairment of protein degradation pathways, accumulation of alpha-synuclein, and apoptotic cell death in aged mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAA3634

Leucine-rich repeat kinase 2 (LRRK2)-deficient rats exhibit renal tubule injury and perturbations in metabolic and immunological homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAA3634

Loss of leucine-rich repeat kinase 2 (LRRK2) in rats leads to progressive abnormal phenotypes in peripheral organs

21 January 2018

1 reference

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Measurement of LRRK2 and Ser910/935 phosphorylated LRRK2 in peripheral blood mononuclear cells from idiopathic Parkinson's disease patients.

21 January 2018

1 reference

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Surfactant secretion in LRRK2 knock-out rats: changes in lamellar body morphology and rate of exocytosis.

21 January 2018

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Biological function of the cellular lipid BMP-BMP as a key activator for cholesterol sorting and membrane digestion

21 January 2018

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Amiodarone: review of pulmonary effects and toxicity

21 January 2018

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Amiodarone-induced pulmonary toxicity: an under-recognized and severe adverse effect?

21 January 2018

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Drug induced phospholipidosis: an acquired lysosomal storage disorder

21 January 2018

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Lysosomal storage disease: revealing lysosomal function and physiology.

21 January 2018

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Zfp423 is required for normal cerebellar development

21 January 2018

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In situ validation of an intestinal stem cell signature in colorectal cancer

21 January 2018

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10.1126/SCITRANSLMED.AAA3634

21 January 2018

Identifiers

DOI

1 reference

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29 February 2020

1 reference