(Q46804912)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18199761%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

title

Glial dysfunction in parkin null mice: effects of aging (English)

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1 January 2020

author name string

Rosa M Solano

1

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1 January 2020

Maria J Casarejos

2

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1 January 2020

Jamie Menéndez-Cuervo

3

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1 January 2020

Jose A Rodriguez-Navarro

4

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1 January 2020

Justo García de Yébenes

5

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1 January 2020

Maria A Mena

6

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1 January 2020

language of work or name

English

0 references

publication date

1 January 2008

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1 January 2020

published in

Journal of Neuroscience

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1 January 2020

volume

28

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1 January 2020

issue

3

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1 January 2020

page(s)

598-611

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A wide variety of mutations in the parkin gene are responsible for autosomal recessive parkinsonism in Europe. French Parkinson's Disease Genetics Study Group and the European Consortium on Genetic Susceptibility in Parkinson's Disease

1 January 2020

cites work

1 reference

12 December 2020

Pharmacological characterization of dopamine transport in cultured rat astrocytes

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12 December 2020

Induction of a midbrain dopaminergic phenotype in Nurr1-overexpressing neural stem cells by type 1 astrocytes.

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12 December 2020

Glial cell participation in the degeneration of dopaminergic neurons in Parkinson's disease

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12 December 2020

Inducible nitric oxide synthase stimulates dopaminergic neurodegeneration in the MPTP model of Parkinson disease

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12 December 2020

The effect of glia-conditioned medium on dopamine neurons in culture. Modulation of apoptosis, tyrosine hydroxylase expression and 1-methyl-4-phenylpyridinium toxicity

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12 December 2020

N-acetylcysteine elicited increase in complex I activity in synaptic mitochondria from aged mice: implications for treatment of Parkinson's disease

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12 December 2020

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12 December 2020

Association between early-onset Parkinson's disease and mutations in the parkin gene

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12 December 2020

Parkin functions as an E2-dependent ubiquitin- protein ligase and promotes the degradation of the synaptic vesicle-associated protein, CDCrel-1

1 reference

12 December 2020

Neurotrophic and neurotoxic effects of nitric oxide on fetal midbrain cultures

1 reference

12 December 2020

Dopamine increases glial cell line-derived neurotrophic factor in human fetal astrocytes

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12 December 2020

Iron accumulation in the substantia nigra of autosomal recessive juvenile parkinsonism (ARJP)

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12 December 2020

The role of glial cells in Parkinson's disease

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12 December 2020

L-DOPA and glia-conditioned medium have additive effects on tyrosine hydroxylase expression in human catecholamine-rich neuroblastoma NB69 cells

1 reference

12 December 2020

Glutathione depletion switches nitric oxide neurotrophic effects to cell death in midbrain cultures: implications for Parkinson's disease

1 reference

12 December 2020

Guidance of dopaminergic neuritic growth by immature astrocytes in organotypic cultures of rat fetal ventral mesencephalon

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12 December 2020

Glutathione decreases in dopaminergic PC12 cells interfere with the ubiquitin protein degradation pathway: relevance for Parkinson's disease?

1 reference

12 December 2020

Blockade of microglial activation is neuroprotective in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson disease.

1 reference

12 December 2020

Astroglia induce neurogenesis from adult neural stem cells

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12 December 2020

Stem cells in the treatment of Parkinson's disease.

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12 December 2020

The role of astroglia on the survival of dopamine neurons.

1 reference

12 December 2020

CHIP is associated with Parkin, a gene responsible for familial Parkinson's disease, and enhances its ubiquitin ligase activity

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12 December 2020

Glutathione, iron and Parkinson's disease

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12 December 2020

Astroglial dopamine transport is mediated by norepinephrine transporter

1 reference

12 December 2020

Astrocytic but not neuronal increased expression and redistribution of parkin during unfolded protein stress

1 reference

12 December 2020

Nitric oxide triggers the toxicity due to glutathione depletion in midbrain cultures through 12-lipoxygenase

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12 December 2020

Immunohistochemical localization of Bcl-2 in the spinal cords of rats with experimental autoimmune encephalomyelitis.

1 reference

12 December 2020

Mitochondria, oxidative damage, and inflammation in Parkinson's disease

1 reference

12 December 2020

Parkin gene inactivation alters behaviour and dopamine neurotransmission in the mouse

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12 December 2020

Parkin-deficient mice exhibit nigrostriatal deficits but not loss of dopaminergic neurons

1 reference

12 December 2020

Glia-conditioned medium induces de novo synthesis of tyrosine hydroxylase and increases dopamine cell survival by differential signaling pathways

1 reference

12 December 2020

Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation

1 reference

12 December 2020

Selective and persistent activation of extracellular signal-regulated protein kinase by nitric oxide in glial cells induces neuronal degeneration in glutathione-depleted midbrain cultures

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12 December 2020

CHIP and Hsp70 regulate tau ubiquitination, degradation and aggregation

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12 December 2020

Mitochondrial dysfunction and oxidative damage in parkin-deficient mice

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12 December 2020

Increased expression of heat shock proteins in rat brain during aging: relationship with mitochondrial function and glutathione redox state.

1 reference

12 December 2020

Astrocyte apoptosis: implications for neuroprotection

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12 December 2020

Loss of locus coeruleus neurons and reduced startle in parkin null mice

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12 December 2020

Cellular pathology of Parkinson's disease: astrocytes, microglia and inflammation

1 reference

12 December 2020

Reduction in endogenous parkin levels renders glial cells sensitive to both caspase-dependent and caspase-independent cell death.

1 reference

12 December 2020

Role of extracellular signal-regulated protein kinase in neuronal cell death induced by glutathione depletion in neuron/glia mesencephalic cultures

1 reference

12 December 2020

BAG5 inhibits parkin and enhances dopaminergic neuron degeneration

1 reference

12 December 2020

Parkin-deficient mice are not a robust model of parkinsonism

1 reference

12 December 2020

Dopamine-derived dopaminochrome promotes H(2)O(2) release at mitochondrial complex I: stimulation by rotenone, control by Ca(2+), and relevance to Parkinson disease

1 reference

12 December 2020

Glutathione depletion resulting in selective mitochondrial complex I inhibition in dopaminergic cells is via an NO-mediated pathway not involving peroxynitrite: implications for Parkinson's disease

1 reference

12 December 2020

Increased glutathione S-transferase activity rescues dopaminergic neuron loss in a Drosophila model of Parkinson's disease

1 reference

12 December 2020

Effects of cinnarizine, a calcium antagonist that produces human parkinsonism, in parkin knock out mice

1 reference

12 December 2020

Differential effects of l-DOPA on monoamine metabolism, cell survival and glutathione production in midbrain neuronal-enriched cultures from parkin knockout and wild-type mice

1 reference

12 December 2020

Inactivation of Drosophila DJ-1 leads to impairments of oxidative stress response and phosphatidylinositol 3-kinase/Akt signaling

1 reference

12 December 2020

Susceptibility to rotenone is increased in neurons from parkin null mice and is reduced by minocycline.

1 reference

12 December 2020

Changed distribution pattern of the constitutive rather than the inducible HSP70 chaperone in neuromelanin-containing neurones of the Parkinsonian midbrain.

1 reference

12 December 2020

Suppression of Parkin enhances nigrostriatal and motor neuron lesion in mice over-expressing human-mutated tau protein

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12 December 2020

Midbrain neuronal cultures from parkin mutant mice are resistant to nitric oxide-induced toxicity.

1 reference

12 December 2020

Glutathione peroxidase 1 and glutathione are required to protect mouse astrocytes from iron-mediated hydrogen peroxide toxicity.

1 reference

12 December 2020

Microglial senescence: does the brain's immune system have an expiration date?

1 reference

12 December 2020

A regulated interaction with the UIM protein Eps15 implicates parkin in EGF receptor trafficking and PI(3)K-Akt signalling

1 reference

12 December 2020

Conditioned media derived from glial cell lines promote survival and differentiation of dopaminergic neurons in vitro: Role of mesencephalic glia

1 reference

12 December 2020

Parkin: a multifaceted ubiquitin ligase.

1 reference

12 December 2020

The etiopathogenesis of Parkinson disease and suggestions for future research. Part I.

1 reference

12 December 2020

Non-cell autonomous effect of glia on motor neurons in an embryonic stem cell-based ALS model

1 reference

12 December 2020

Astrocytes expressing ALS-linked mutated SOD1 release factors selectively toxic to motor neurons

1 reference

12 December 2020

The etiopathogenesis of Parkinson disease and suggestions for future research. Part II.

1 reference

12 December 2020

Mortality, oxidative stress and tau accumulation during ageing in parkin null mice

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12 December 2020

Oestrogen regulates the expression and function of dopamine transporters in astrocytes of the nigrostriatal system

1 reference

12 December 2020

The distribution of microglia and cell death in the fetal rat forebrain

1 reference

12 December 2020

Inhibition of NADH-linked oxidation in brain mitochondria by 1-methyl-4-phenyl-pyridine, a metabolite of the neurotoxin, 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine.

1 reference

12 December 2020

Uptake of the neurotoxin 1-methyl-4-phenylpyridine (MPP+) by mitochondria and its relation to the inhibition of the mitochondrial oxidation of NAD+-linked substrates by MPP+

1 reference

12 December 2020

Transition Metals, Ferritin, Glutathione, and Ascorbic Acid in Parkinsonian Brains

1 reference

12 December 2020

A spectrophotometric method for determination of catalase activity in small tissue samples

1 reference

12 December 2020

Energy-dependent uptake of N-methyl-4-phenylpyridinium, the neurotoxic metabolite of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine, by mitochondria.

1 reference

12 December 2020

Lectin binding by resting and reactive microglia

1 reference

12 December 2020

Cell-type-specific markers for distinguishing and studying neurons and the major classes of glial cells in culture

1 reference

12 December 2020

Enzymic method for quantitative determination of nanogram amounts of total and oxidized glutathione: applications to mammalian blood and other tissues

1 reference

12 December 2020

Glutathione S-transferases. The first enzymatic step in mercapturic acid formation

1 reference

12 December 2020

A glial progenitor cell that develops in vitro into an astrocyte or an oligodendrocyte depending on culture medium

1 reference

12 December 2020

Assays of glutathione peroxidase

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12 December 2020

Determination of glutathione and glutathione disulfide using glutathione reductase and 2-vinylpyridine

1 reference

12 December 2020

A synthetic inhibitor of the mitogen-activated protein kinase cascade

1 reference

12 December 2020

Astroglial neurotrophic and neurite-promoting factors

1 reference

12 December 2020

Vitamin E, ascorbate, glutathione, glutathione disulfide, and enzymes of glutathione metabolism in cultures of chick astrocytes and neurons: evidence that astrocytes play an important role in antioxidative processes in the brain.

1 reference

12 December 2020

Glutathione peroxidase, glial cells and Parkinson's disease.

1 reference

12 December 2020

Levodopa toxicity in foetal rat midbrain neurones in culture: modulation by ascorbic acid.

1 reference

12 December 2020

Depletion of brain glutathione results in a decrease of glutathione reductase activity; an enzyme susceptible to oxidative damage.

1 reference

12 December 2020

Evidence for a novel neurotrophic factor for dopaminergic neurons secreted from mesencephalic glial cell lines

1 reference

12 December 2020

HSP70 protects murine astrocytes from glucose deprivation injury.

1 reference

12 December 2020

Effects of wild-type and mutated copper/zinc superoxide dismutase on neuronal survival and L-DOPA-induced toxicity in postnatal midbrain culture

1 reference

12 December 2020

Involvement of glutathione peroxidase and catalase in the disposal of exogenous hydrogen peroxide by cultured astroglial cells.

1 reference

12 December 2020

Glia protect fetal midbrain dopamine neurons in culture from L-DOPA toxicity through multiple mechanisms

1 reference

12 December 2020

Regulation of ubiquitin-conjugating enzymes by glutathione following oxidative stress

1 reference

12 December 2020

Neuronal-enriched cultures from embryonic rat ventral mesencephalon for pharmacological studies of dopamine neurons.

1 reference

12 December 2020

Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism

1 reference

12 December 2020

Identification of a novel inhibitor of mitogen-activated protein kinase kinase

1 reference

12 December 2020

A synergistic neurotrophic response to l-dihydroxyphenylalanine and nerve growth factor

1 reference

12 December 2020

10.1523/JNEUROSCI.4609-07.2008

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18199761%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18199761%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

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