(Q46814179)

25 December 2017

title

Aggressive amyloidosis in mice expressing human amyloid peptides with the Arctic mutation (English)

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25 December 2017

6

Lennart Mucke

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25 December 2017

author name string

Irene H Cheng

1

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25 December 2017

Jorge J Palop

2

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25 December 2017

Luke A Esposito

3

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25 December 2017

Nga Bien-Ly

4

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25 December 2017

Fengrong Yan

5

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25 December 2017

language of work or name

English

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publication date

24 October 2004

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25 December 2017

published in

Nature Medicine

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25 December 2017

volume

10

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25 December 2017

issue

11

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25 December 2017

page(s)

1190-1192

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25 December 2017

https://scigraph.springernature.com/pub.10.1038/nm1123

exact match

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cites work

Alzheimer's disease: molecular understanding predicts amyloid-based therapeutics

1 reference

Protofibrils, pores, fibrils, and neurodegeneration: separating the responsible protein aggregates from the innocent bystanders

21 January 2018

1 reference

The 'Arctic' APP mutation (E693G) causes Alzheimer's disease by enhanced Abeta protofibril formation

21 January 2018

1 reference

Oligomeric and fibrillar species of amyloid-beta peptides differentially affect neuronal viability.

21 January 2018

1 reference

Neurotoxicity and physicochemical properties of Abeta mutant peptides from cerebral amyloid angiopathy: implication for the pathogenesis of cerebral amyloid angiopathy and Alzheimer's disease

21 January 2018

1 reference

Neuronal depletion of calcium-dependent proteins in the dentate gyrus is tightly linked to Alzheimer's disease-related cognitive deficits

21 January 2018

1 reference

The Arctic mutation interferes with processing of the amyloid precursor protein

21 January 2018

1 reference

Clusterin promotes amyloid plaque formation and is critical for neuritic toxicity in a mouse model of Alzheimer's disease

21 January 2018

1 reference

Dutch, Flemish, Italian, and Arctic mutations of APP and resistance of Abeta to physiologically relevant proteolytic degradation.

21 January 2018

1 reference

Differential degradation of amyloid beta genetic variants associated with hereditary dementia or stroke by insulin-degrading enzyme

21 January 2018

1 reference

Abeta is targeted to the vasculature in a mouse model of hereditary cerebral hemorrhage with amyloidosis.

21 January 2018

1 reference

Alzheimer-type neuropathology in transgenic mice overexpressing V717F β-amyloid precursor protein

21 January 2018

1 reference

The use of seldi proteinchip arrays to monitor production of Alzheimer's betaamyloid in transfected cells.

21 January 2018

1 reference

High-level neuronal expression of abeta 1-42 in wild-type human amyloid protein precursor transgenic mice: synaptotoxicity without plaque formation

21 January 2018

1 reference

inferred from DOI database lookup

7 January 2021

based on heuristic

Identification and transport of full-length amyloid precursor proteins in rat peripheral nervous system.

1 reference

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/NM1123

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25 December 2017

Dimensions Publication ID

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25 December 2017