(Q46841230)

25 December 2017

title

Drugs affecting prelamin A processing: effects on heterochromatin organization (English)

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25 December 2017

author

Cristina Capanni

3

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25 December 2017

Spartaco Santi

4

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25 December 2017

Giuseppe Novelli

7

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25 December 2017

Stefano Squarzoni

9

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25 December 2017

Giovanna Lattanzi

11

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25 December 2017

Elisabetta Mattioli

Elisabetta Mattioli

1

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Roland Foisner

10

Roland Foisner

1 reference

25 December 2017

Nadir Mario Maraldi

5

Nadir M Maraldi

1 reference

25 December 2017

Marta Columbaro

2

Marta Columbaro

1 reference

25 December 2017

Massimo Riccio

8

Massimo Riccio

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25 December 2017

author name string

M Rosaria D'Apice

6

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25 December 2017

language of work or name

English

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publication date

24 November 2007

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25 December 2017

Experimental Cell Research

published in

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25 December 2017

volume

314

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25 December 2017

issue

3

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25 December 2017

page(s)

453-462

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25 December 2017

Prelamin A endoproteolytic processing in vitro by recombinant Zmpste24

cites work

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2007.11.012

Zmpste24 deficiency in mice causes spontaneous bone fractures, muscle weakness, and a prelamin A processing defect.

7 January 2021

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Farnesylated lamins, progeroid syndromes and farnesyl transferase inhibitors

7 January 2021

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Recurrent de novo point mutations in lamin A cause Hutchinson–Gilford progeria syndrome

7 January 2021

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Altered pre-lamin A processing is a common mechanism leading to lipodystrophy.

7 January 2021

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Alterations of nuclear envelope and chromatin organization in mandibuloacral dysplasia, a rare form of laminopathy

7 January 2021

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Loss of ZMPSTE24 (FACE-1) causes autosomal recessive restrictive dermopathy and accumulation of Lamin A precursors.

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Nuclear lamins: laminopathies and their role in premature ageing.

7 January 2021

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Nuclear lamins, diseases and aging

7 January 2021

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Prelamin A farnesylation and progeroid syndromes

7 January 2021

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Incomplete processing of mutant lamin A in Hutchinson-Gilford progeria leads to nuclear abnormalities, which are reversed by farnesyltransferase inhibition

7 January 2021

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A protein farnesyltransferase inhibitor ameliorates disease in a mouse model of progeria.

7 January 2021

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Rescue of heterochromatin organization in Hutchinson-Gilford progeria by drug treatment

7 January 2021

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Mutant nuclear lamin A leads to progressive alterations of epigenetic control in premature aging

7 January 2021

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Reversal of the cellular phenotype in the premature aging disease Hutchinson-Gilford progeria syndrome

7 January 2021

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In vitro assay and characterization of the farnesylation-dependent prelamin A endoprotease

7 January 2021

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A rapid, reversible, and tunable method to regulate protein function in living cells using synthetic small molecules

7 January 2021

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Experimental condensation inhibition in constitutive and facultative heterochromatin of mammalian chromosomes

7 January 2021

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Characterization of the functional activities of the bovine papillomavirus type 1 E2 protein single-chain heterodimers

7 January 2021

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Defective prelamin A processing and muscular and adipocyte alterations in Zmpste24 metalloproteinase-deficient mice.

7 January 2021

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A phosphorylation cluster in the chromatin-binding region regulates chromosome association of LAP2alpha

7 January 2021

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Pre-Lamin A processing is linked to heterochromatin organization.

7 January 2021

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Thymopoietin (lamina-associated polypeptide 2) gene mutation associated with dilated cardiomyopathy

7 January 2021

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Characterization of a human carcinoma cell line selected for resistance to the farnesyl transferase inhibitor 4-(2-(4-(8-chloro-3,10-dibromo-6,11-dihydro-5H-benzo-(5,6)-cyclohepta(1,2-b)-pyridin-11(R)-yl)-1-piperidinyl)-2-oxo-ethyl)-1-piperidinecarb

7 January 2021

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Ras CAAX Peptidomimetic FTI-277 Selectively Blocks Oncogenic Ras Signaling by Inducing Cytoplasmic Accumulation of Inactive Ras-Raf Complexes

7 January 2021

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Farnesyltransferase and geranylgeranyltransferase I inhibitors upregulate RhoB expression by HDAC1 dissociation, HAT association and histone acetylation of the RhoB promoter.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2007.11.012

DNA methyltransferase 1 knockdown activates a replication stress checkpoint.

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YEXCR.2007.11.012

Accumulation of mutant lamin A causes progressive changes in nuclear architecture in Hutchinson-Gilford progeria syndrome

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2007.11.012

Laminopathies: involvement of structural nuclear proteins in the pathogenesis of an increasing number of human diseases

7 January 2021

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10.1016/J.YEXCR.2007.11.012

7 January 2021

Identifiers

DOI

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25 December 2017

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25 December 2017