(Q46847122)

25 December 2017

title

'Tuning' of type I interferon-induced Jak-STAT1 signaling by calcium-dependent kinases in macrophages (English)

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25 December 2017

6

Joseph Schlessinger

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25 December 2017

Lu Wang

1

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25 December 2017

Ioannis Tassiulas

2

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25 December 2017

Kyung-Hyun Park-Min

3

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25 December 2017

Alicia C Reid

4

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25 December 2017

Hava Gil-Henn

5

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25 December 2017

Roland Baron

7

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25 December 2017

J Jillian Zhang

8

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25 December 2017

Lionel B Ivashkiv

9

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25 December 2017

language of work or name

English

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publication date

16 December 2007

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25 December 2017

published in

Nature Immunology

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25 December 2017

volume

9

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25 December 2017

page(s)

186-193

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25 December 2017

issue

2

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25 December 2017

Cutting edge: inhibition of TLR and FcR responses in macrophages by triggering receptor expressed on myeloid cells (TREM)-2 and DAP12.

cites work

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Cutting Edge: TREM-2 Attenuates Macrophage Activation

21 January 2018

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Functional subdomains of STAT2 required for preassociation with the alpha interferon receptor and for signaling

21 January 2018

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CaM kinase II-dependent activation of tyrosine kinases and ERK1/2 in vascular smooth muscle

21 January 2018

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Inhibition of immune responses by ITAM-bearing receptors

21 January 2018

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7 January 2021

Activating and inhibitory functions of DAP12.

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7 January 2021

The many faces of ITAMs.

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7 January 2021

The molecular understanding of osteoclast differentiation

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7 January 2021

Crosstalk among Jak-STAT, Toll-like receptor, and ITAM-dependent pathways in macrophage activation

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7 January 2021

Amplification of IFN-alpha-induced STAT1 activation and inflammatory function by Syk and ITAM-containing adaptors

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7 January 2021

Evidence for the requirement of ITAM domains but not SLP-76/Gads interaction for integrin signaling in hematopoietic cells.

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7 January 2021

Integrin signaling in neutrophils and macrophages uses adaptors containing immunoreceptor tyrosine-based activation motifs

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7 January 2021

Syk, c-Src, the alphavbeta3 integrin, and ITAM immunoreceptors, in concert, regulate osteoclastic bone resorption

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7 January 2021

TREM-1 amplifies inflammation and is a crucial mediator of septic shock

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7 January 2021

DAP12 (KARAP) amplifies inflammation and increases mortality from endotoxemia and septic peritonitis

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7 January 2021

Stats: transcriptional control and biological impact

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7 January 2021

Requirement of Ca2+ and CaMKII for Stat1 Ser-727 phosphorylation in response to IFN-gamma

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7 January 2021

Requirement of serine phosphorylation for formation of STAT-promoter complexes

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7 January 2021

Complex modulation of cell type-specific signaling in response to type I interferons

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7 January 2021

Regulation of JAK-STAT signalling in the immune system

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7 January 2021

Ca(2+)/CaM-dependent kinases: from activation to function

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7 January 2021

The immunomodulatory adapter proteins DAP12 and Fc receptor gamma-chain (FcRgamma) regulate development of functional osteoclasts through the Syk tyrosine kinase

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7 January 2021

Role of STAT3 in type I interferon responses. Negative regulation of STAT1-dependent inflammatory gene activation

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7 January 2021

RAFTK/Pyk2-mediated cellular signalling

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7 January 2021

Interleukin (IL)-7 induces rapid activation of Pyk2, which is bound to Janus kinase 1 and IL-7Ralpha

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7 January 2021

Protein tyrosine kinase PYK2 involved in Ca(2+)-induced regulation of ion channel and MAP kinase functions

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7 January 2021

Pyk2 is a downstream mediator of the IL-2 receptor-coupled Jak signaling pathway

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7 January 2021

Protein tyrosine kinase Pyk2 mediates the Jak-dependent activation of MAPK and Stat1 in IFN-gamma, but not IFN-alpha, signaling

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7 January 2021

A calcium-dependent tyrosine kinase splice variant in human monocytes. Activation by a two-stage process involving adherence and a subsequent intracellular signal

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7 January 2021

Pyk2 regulates multiple signaling events crucial for macrophage morphology and migration

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7 January 2021

Cbl associates with Pyk2 and Src to regulate Src kinase activity, alpha(v)beta(3) integrin-mediated signaling, cell adhesion, and osteoclast motility

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7 January 2021

Kinase-negative mutants of JAK1 can sustain interferon-gamma-inducible gene expression but not an antiviral state

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7 January 2021

Interferon-alpha-dependent activation of Tyk2 requires phosphorylation of positive regulatory tyrosines by another kinase

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7 January 2021

Differential activation of transcription factors induced by Ca2+ response amplitude and duration

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7 January 2021

Different nuclear signals are activated by the B cell receptor during positive versus negative signaling.

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7 January 2021

Syk is required for integrin signaling in neutrophils

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7 January 2021

Inositol trisphosphate and calcium signalling

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7 January 2021

Src and Pyk2 mediate G-protein-coupled receptor activation of epidermal growth factor receptor (EGFR) but are not required for coupling to the mitogen-activated protein (MAP) kinase signaling cascade

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7 January 2021

EGFR signal transactivation in cancer cells

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7 January 2021

TLR-dependent and TLR-independent pathways of type I interferon induction in systemic autoimmunity

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7 January 2021

Type I interferon modulation of cellular responses to cytokines and infectious pathogens: potential role in SLE pathogenesis

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7 January 2021

Induction and activation of the transcription factor NFATc1 (NFAT2) integrate RANKL signaling in terminal differentiation of osteoclasts

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7 January 2021

G protein-coupled receptor activation rapidly stimulates focal adhesion kinase phosphorylation at Ser-843. Mediation by Ca2+, calmodulin, and Ca2+/calmodulin-dependent kinase II.

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7 January 2021

Critical role of the carboxyl terminus of proline-rich tyrosine kinase (Pyk2) in the activation of human neutrophils by tumor necrosis factor: separation of signals for the respiratory burst and degranulation

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7 January 2021

Pyk2 amplifies epidermal growth factor and c-Src-induced Stat3 activation

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7 January 2021

Selective regulation of IL-10 signaling and function by zymosan

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7 January 2021

Inhibition of interleukin 10 signaling after Fc receptor ligation and during rheumatoid arthritis

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7 January 2021

Selective blockade of the inhibitory Fcgamma receptor (FcgammaRIIB) in human dendritic cells and monocytes induces a type I interferon response program

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7 January 2021

Src kinase activity is essential for osteoclast function

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7 January 2021

Identifiers

DOI

10.1038/NI1548

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25 December 2017

PubMed ID

18084294

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25 December 2017