(Q46865899)

English

Rat hindlimb unloading down-regulates insulin like growth factor-1 signaling and AMP-activated protein kinase, and leads to severe atrophy of the soleus muscle

scientific article published in December 2007

In more languages

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scholarly article

1 reference

Europe PubMed Central

25 December 2017

http://europepmc.org/abstract/MED/18059585

Rat hindlimb unloading down-regulates insulin like growth factor-1 signaling and AMP-activated protein kinase, and leads to severe atrophy of the soleus muscle (English)

1 reference

Europe PubMed Central

25 December 2017

http://europepmc.org/abstract/MED/18059585

author name string

Bing Han

1

1 reference

Europe PubMed Central

25 December 2017

http://europepmc.org/abstract/MED/18059585

Mei J Zhu

2

1 reference

Europe PubMed Central

25 December 2017

http://europepmc.org/abstract/MED/18059585

Changwei Ma

3

1 reference

Europe PubMed Central

25 December 2017

http://europepmc.org/abstract/MED/18059585

Min Du

4

1 reference

Europe PubMed Central

25 December 2017

http://europepmc.org/abstract/MED/18059585

publication date

1 December 2007

1 reference

Europe PubMed Central

25 December 2017

http://europepmc.org/abstract/MED/18059585

Applied Physiology, Nutrition, and Metabolism

1 reference

Europe PubMed Central

25 December 2017

http://europepmc.org/abstract/MED/18059585

32

1 reference

Europe PubMed Central

25 December 2017

http://europepmc.org/abstract/MED/18059585

1115-1123

1 reference

Europe PubMed Central

25 December 2017

http://europepmc.org/abstract/MED/18059585

6

1 reference

Europe PubMed Central

25 December 2017

http://europepmc.org/abstract/MED/18059585

Skeletal muscle unweighting: spaceflight and ground-based models

1 reference

https://api.crossref.org/works/10.1139%2FH07-102

21 January 2018

Basal and evoked levels of bioassayable growth hormone are altered by hindlimb unloading

1 reference

https://api.crossref.org/works/10.1139%2FH07-102

21 January 2018

Skeletal unloading induces resistance to insulin-like growth factor I.

1 reference

https://api.crossref.org/works/10.1139%2FH07-102

21 January 2018

Fuel homeostasis during physical inactivity induced by bed rest.

1 reference

https://api.crossref.org/works/10.1139%2FH07-102

21 January 2018

Identification of ubiquitin ligases required for skeletal muscle atrophy

1 reference

https://api.crossref.org/works/10.1139%2FH07-102

21 January 2018

Akt/mTOR pathway is a crucial regulator of skeletal muscle hypertrophy and can prevent muscle atrophy in vivo

1 reference

https://api.crossref.org/works/10.1139%2FH07-102

21 January 2018

Immediate response of mammalian target of rapamycin (mTOR)-mediated signalling following acute resistance exercise in rat skeletal muscle

1 reference

https://api.crossref.org/works/10.1139%2FH07-102

21 January 2018

Translational control of protein synthesis in muscle and liver of growth hormone-treated pigs

1 reference

https://api.crossref.org/works/10.1139%2FH07-102

21 January 2018

Thr2446 is a novel mammalian target of rapamycin (mTOR) phosphorylation site regulated by nutrient status

1 reference

https://api.crossref.org/works/10.1139%2FH07-102

21 January 2018

Phosphorylation of mammalian target of rapamycin (mTOR) at Ser-2448 is mediated by p70S6 kinase

1 reference

https://api.crossref.org/works/10.1139%2FH07-102

21 January 2018

Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B

1 reference

https://api.crossref.org/works/10.1139%2FH07-102

21 January 2018

Effect of nutrient restriction on calpain and calpastatin content of skeletal muscle from cows and fetuses.

1 reference

https://api.crossref.org/works/10.1139%2FH07-102

21 January 2018

Effect of unloading on type I myosin heavy chain gene regulation in rat soleus muscle

1 reference

https://api.crossref.org/works/10.1139%2FH07-102

21 January 2018

Atrophy responses to muscle inactivity. II. Molecular markers of protein deficits

1 reference

https://api.crossref.org/works/10.1139%2FH07-102

21 January 2018

Isometric resistance exercise fails to counteract skeletal muscle atrophy processes during the initial stages of unloading

1 reference

https://api.crossref.org/works/10.1139%2FH07-102

21 January 2018

Raptor, a binding partner of target of rapamycin (TOR), mediates TOR action

1 reference

https://api.crossref.org/works/10.1139%2FH07-102

21 January 2018

AMP-activated protein kinase: a key system mediating metabolic responses to exercise

1 reference

https://api.crossref.org/works/10.1139%2FH07-102

21 January 2018

Glycogen synthase kinase-3beta: a novel regulator of cardiac hypertrophy and development.

1 reference

https://api.crossref.org/works/10.1139%2FH07-102

21 January 2018

Calmodulin-dependent protein kinase kinase-beta is an alternative upstream kinase for AMP-activated protein kinase

1 reference

https://api.crossref.org/works/10.1139%2FH07-102

21 January 2018

Skeletal muscle lipid content and oxidative enzyme activity in relation to muscle fiber type in type 2 diabetes and obesity.

1 reference

https://api.crossref.org/works/10.1139%2FH07-102

21 January 2018

Transcriptional regulation of the type I myosin heavy chain promoter in inactive rat soleus

1 reference

https://api.crossref.org/works/10.1139%2FH07-102

21 January 2018

TSC2 mediates cellular energy response to control cell growth and survival

1 reference

https://api.crossref.org/works/10.1139%2FH07-102

21 January 2018

5'-AMP-activated protein kinase phosphorylates IRS-1 on Ser-789 in mouse C2C12 myotubes in response to 5-aminoimidazole-4-carboxamide riboside

1 reference

https://api.crossref.org/works/10.1139%2FH07-102

21 January 2018

Increased activation of the mammalian target of rapamycin pathway in liver and skeletal muscle of obese rats: possible involvement in obesity-linked insulin resistance.

1 reference

https://api.crossref.org/works/10.1139%2FH07-102

21 January 2018

Postcontraction insulin sensitivity: relationship with contraction protocol, glycogen concentration, and 5' AMP-activated protein kinase phosphorylation

1 reference

https://api.crossref.org/works/10.1139%2FH07-102

21 January 2018

Insulin-like growth factor-1 (IGF-1) inversely regulates atrophy-induced genes via the phosphatidylinositol 3-kinase/Akt/mammalian target of rapamycin (PI3K/Akt/mTOR) pathway

1 reference

https://api.crossref.org/works/10.1139%2FH07-102

21 January 2018

Atrophy of S6K1(-/-) skeletal muscle cells reveals distinct mTOR effectors for cell cycle and size control.

1 reference

https://api.crossref.org/works/10.1139%2FH07-102

21 January 2018

Development of whole-body and skeletal muscle insulin resistance after one day of hindlimb suspension

1 reference

https://api.crossref.org/works/10.1139%2FH07-102

21 January 2018

Enhanced insulin action on glucose transport and insulin signaling in 7-day unweighted rat soleus muscle

1 reference

https://api.crossref.org/works/10.1139%2FH07-102

21 January 2018

A phosphatidylinositol 3-kinase/Akt/mTOR pathway mediates and PTEN antagonizes tumor necrosis factor inhibition of insulin signaling through insulin receptor substrate-1.

1 reference

https://api.crossref.org/works/10.1139%2FH07-102

21 January 2018

Role of translation initiation factor 2B in control of cell survival by the phosphatidylinositol 3-kinase/Akt/glycogen synthase kinase 3beta signaling pathway

1 reference

https://api.crossref.org/works/10.1139%2FH07-102

21 January 2018

Skeletal myocyte hypertrophy requires mTOR kinase activity and S6K1.

1 reference

https://api.crossref.org/works/10.1139%2FH07-102

21 January 2018

TNF-alpha and insulin resistance: summary and future prospects

1 reference

https://api.crossref.org/works/10.1139%2FH07-102

21 January 2018

Enhancement of hybrid-fiber types in rat soleus muscle after clenbuterol administration during hindlimb unloading

1 reference

https://api.crossref.org/works/10.1139%2FH07-102

21 January 2018

IGF-I stimulates muscle growth by suppressing protein breakdown and expression of atrophy-related ubiquitin ligases, atrogin-1 and MuRF1.

1 reference

https://api.crossref.org/works/10.1139%2FH07-102

21 January 2018

Akt signaling in skeletal muscle: regulation by exercise and passive stretch

1 reference

https://api.crossref.org/works/10.1139%2FH07-102

21 January 2018

Skeletal unloading induces resistance to insulin-like growth factor I on bone formation.

1 reference

https://api.crossref.org/works/10.1139%2FH07-102

21 January 2018

Skeletal unloading induces resistance to insulin-like growth factor-I (IGF-I) by inhibiting activation of the IGF-I signaling pathways

1 reference

https://api.crossref.org/works/10.1139%2FH07-102

21 January 2018

AMP-activated protein kinase (AMPK) control of fatty acid and glucose metabolism in the ischemic heart

1 reference

https://api.crossref.org/works/10.1139%2FH07-102

21 January 2018

TOR, a central controller of cell growth

1 reference

https://api.crossref.org/works/10.1139%2FH07-102

21 January 2018

Calcineurin signaling and NFAT activation in cardiovascular and skeletal muscle development

1 reference

https://api.crossref.org/works/10.1139%2FH07-102

21 January 2018

Insulin and IGF-I stimulate the formation of the eukaryotic initiation factor 4F complex and protein synthesis in C2C12 myotubes independent of availability of external amino acids

1 reference

https://api.crossref.org/works/10.1139%2FH07-102

21 January 2018

Insulin-like growth factor I-mediated skeletal muscle hypertrophy is characterized by increased mTOR-p70S6K signaling without increased Akt phosphorylation

1 reference

https://api.crossref.org/works/10.1139%2FH07-102

21 January 2018

Insulin-like growth factor 1 inhibits extracellular signal-regulated kinase to promote neuronal survival via the phosphatidylinositol 3-kinase/protein kinase A/c-Raf pathway.

1 reference

https://api.crossref.org/works/10.1139%2FH07-102

21 January 2018

Effects of chronic AICAR treatment on fiber composition, enzyme activity, UCP3, and PGC-1 in rat muscles.

1 reference

https://api.crossref.org/works/10.1139%2FH07-102

21 January 2018

Metformin increases the PGC-1alpha protein and oxidative enzyme activities possibly via AMPK phosphorylation in skeletal muscle in vivo

1 reference

https://api.crossref.org/works/10.1139%2FH07-102

21 January 2018

Insulin secretion and sensitivity in space flight: diabetogenic effects

1 reference

https://api.crossref.org/works/10.1139%2FH07-102

21 January 2018

Absence of S6K1 protects against age- and diet-induced obesity while enhancing insulin sensitivity

1 reference

https://api.crossref.org/works/10.1139%2FH07-102

21 January 2018

IGF-I stimulates protein synthesis in skeletal muscle through multiple signaling pathways during sepsis

1 reference

https://api.crossref.org/works/10.1139%2FH07-102

21 January 2018

Ca2+/calmodulin-dependent protein kinase kinase-beta acts upstream of AMP-activated protein kinase in mammalian cells.

1 reference

https://api.crossref.org/works/10.1139%2FH07-102

21 January 2018

Effect of maternal nutrient restriction in sheep on the development of fetal skeletal muscle

1 reference

https://api.crossref.org/works/10.1139%2FH07-102

21 January 2018

Maternal nutrient restriction affects properties of skeletal muscle in offspring.

1 reference

https://api.crossref.org/works/10.1139%2FH07-102

21 January 2018

Identifiers

10.1139/H07-102

1 reference

Europe PubMed Central

25 December 2017

http://europepmc.org/abstract/MED/18059585

1 reference

Europe PubMed Central

25 December 2017

http://europepmc.org/abstract/MED/18059585

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