(Q46895149)

English

Piperine, an alkaloid from black pepper, inhibits growth of human colon cancer cells via G1 arrest and apoptosis triggered by endoplasmic reticulum stress

scientific article published on 13 May 2014

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

26 December 2017

http://europepmc.org/abstract/MED/24819444

Piperine, an alkaloid from black pepper, inhibits growth of human colon cancer cells via G1 arrest and apoptosis triggered by endoplasmic reticulum stress (English)

1 reference

Europe PubMed Central

PubMed publication ID

26 December 2017

http://europepmc.org/abstract/MED/24819444

endoplasmic reticulum

1 reference

based on heuristic

inferred from title

1 reference

based on heuristic

inferred from title

author name string

Paul B Yaffe

1

1 reference

Europe PubMed Central

PubMed publication ID

26 December 2017

http://europepmc.org/abstract/MED/24819444

Melanie R Power Coombs

2

1 reference

Europe PubMed Central

PubMed publication ID

26 December 2017

http://europepmc.org/abstract/MED/24819444

Carolyn D Doucette

3

1 reference

Europe PubMed Central

PubMed publication ID

26 December 2017

http://europepmc.org/abstract/MED/24819444

Mark Walsh

4

1 reference

Europe PubMed Central

PubMed publication ID

26 December 2017

http://europepmc.org/abstract/MED/24819444

David W Hoskin

5

1 reference

Europe PubMed Central

PubMed publication ID

26 December 2017

http://europepmc.org/abstract/MED/24819444

publication date

13 May 2014

1 reference

Europe PubMed Central

PubMed publication ID

26 December 2017

http://europepmc.org/abstract/MED/24819444

Molecular Carcinogenesis

1 reference

Europe PubMed Central

PubMed publication ID

26 December 2017

http://europepmc.org/abstract/MED/24819444

54

1 reference

Europe PubMed Central

PubMed publication ID

26 December 2017

http://europepmc.org/abstract/MED/24819444

10

1 reference

Europe PubMed Central

PubMed publication ID

26 December 2017

http://europepmc.org/abstract/MED/24819444

1070-1085

1 reference

Europe PubMed Central

PubMed publication ID

26 December 2017

http://europepmc.org/abstract/MED/24819444

Clinical update: colon, rectal, and anal cancers

1 reference

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21 January 2018

Identifying molecular targets of lifestyle modifications in colon cancer prevention

1 reference

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21 January 2018

Fruit and vegetables in cancer prevention

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21 January 2018

Cancer cell signaling pathways targeted by spice-derived nutraceuticals

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21 January 2018

Alkaloids in the human food chain--natural occurrence and possible adverse effects

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21 January 2018

Piper nigrum and piperine: an update.

1 reference

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21 January 2018

Piperine derived from black pepper increases the plasma levels of coenzyme Q10 following oral supplementation.

1 reference

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21 January 2018

Piperine, a major constituent of black pepper, inhibits human P-glycoprotein and CYP3A4.

1 reference

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21 January 2018

Curcuminoids inhibit multiple human cytochromes P450, UDP-glucuronosyltransferase, and sulfotransferase enzymes, whereas piperine is a relatively selective CYP3A4 inhibitor

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21 January 2018

Piperine inhibits lipopolysaccharide-induced maturation of bone-marrow-derived dendritic cells through inhibition of ERK and JNK activation.

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21 January 2018

Piperine inhibits IL-β induced expression of inflammatory mediators in human osteoarthritis chondrocyte

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21 January 2018

Piperine, the main alkaloid of Thai black pepper, protects against neurodegeneration and cognitive impairment in animal model of cognitive deficit like condition of Alzheimer's disease

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21 January 2018

Protective effect of piperine on benzo(a)pyrene-induced lung carcinogenesis in Swiss albino mice

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21 January 2018

Targeting breast stem cells with the cancer preventive compounds curcumin and piperine

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21 January 2018

Piperine impairs cell cycle progression and causes reactive oxygen species-dependent apoptosis in rectal cancer cells

1 reference

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21 January 2018

Piperine, a Bioactive Component of Pepper Spice Exerts Therapeutic Effects on Androgen Dependent and Androgen Independent Prostate Cancer Cells

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21 January 2018

Antitumor efficacy of piperine in the treatment of human HER2-overexpressing breast cancer cells

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21 January 2018

Piperine suppresses tumor growth and metastasis in vitro and in vivo in a 4T1 murine breast cancer model

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21 January 2018

Effect of piperine on the inhibition of lung metastasis induced B16F-10 melanoma cells in mice

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21 January 2018

Piperine, a dietary phytochemical, inhibits angiogenesis

1 reference

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21 January 2018

Piperine, a piperidine alkaloid from Piper nigrum re-sensitizes P-gp, MRP1 and BCRP dependent multidrug resistant cancer cells

1 reference

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21 January 2018

Resveratrol and piperine enhance radiosensitivity of tumor cells.

1 reference

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21 January 2018

Requirement for p53 and p21 to sustain G2 arrest after DNA damage

1 reference

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21 January 2018

Activation of TRPV1 and TRPA1 by black pepper components

1 reference

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21 January 2018

Characterization using FLIPR of rat vanilloid receptor (rVR1) pharmacology

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21 January 2018

Identification and characterisation of SB-366791, a potent and selective vanilloid receptor (VR1/TRPV1) antagonist.

1 reference

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21 January 2018

CDK inhibitors: positive and negative regulators of G1-phase progression

1 reference

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21 January 2018

Mitochondrial dynamics and apoptosis

1 reference

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21 January 2018

Signalling apoptosis: a radical approach.

1 reference

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21 January 2018

Research strategies in the study of the pro-oxidant nature of polyphenol nutraceuticals

1 reference

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21 January 2018

Pipernonaline from Piper longum Linn. induces ROS-mediated apoptosis in human prostate cancer PC-3 cells

1 reference

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21 January 2018

Integrating the mechanisms of apoptosis induced by endoplasmic reticulum stress

1 reference

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21 January 2018

Stress management at the ER: regulators of ER stress-induced apoptosis

1 reference

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21 January 2018

SP600125, an anthrapyrazolone inhibitor of Jun N-terminal kinase

1 reference

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21 January 2018

p38 mitogen-activated protein kinase inhibitors--mechanisms and therapeutic potentials

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21 January 2018

PI3K and Akt as molecular targets for cancer therapy: current clinical outcomes

1 reference

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21 January 2018

Ceramide inhibits protein kinase B/Akt by promoting dephosphorylation of serine 473.

1 reference

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21 January 2018

Transforming growth factor beta induces apoptosis through repressing the phosphoinositide 3-kinase/AKT/survivin pathway in colon cancer cells

1 reference

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21 January 2018

YM155, a novel small-molecule survivin suppressant, induces regression of established human hormone-refractory prostate tumor xenografts.

1 reference

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21 January 2018

Differential sensitivities of the MRP gene family and gamma-glutamylcysteine synthetase to prooxidants in human colorectal carcinoma cell lines with different p53 status

1 reference

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21 January 2018

Caspases - an update

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Involvement of poly(ADP-ribose) polymerase in base excision repair

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A molecular view on signal transduction by the apoptosome

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Hydroxyl radical generation during mitochondrial electron transfer and the formation of 8-hydroxydesoxyguanosine in mitochondrial DNA.

1 reference

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Oxidative stress in apoptosis and cancer: an update.

1 reference

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21 January 2018

Coupling of stress in the ER to activation of JNK protein kinases by transmembrane protein kinase IRE1

1 reference

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21 January 2018

Chemical biology investigation of cell death pathways activated by endoplasmic reticulum stress reveals cytoprotective modulators of ASK1.

1 reference

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21 January 2018

JNK activation mediates the apoptosis of xCT-deficient cells.

1 reference

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21 January 2018

Stress-induced phosphorylation and activation of the transcription factor CHOP (GADD153) by p38 MAP Kinase

1 reference

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21 January 2018

Gadd153 sensitizes cells to endoplasmic reticulum stress by down-regulating Bcl2 and perturbing the cellular redox state

1 reference

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21 January 2018

ER stress triggers apoptosis by activating BH3-only protein Bim

1 reference

https://api.crossref.org/works/10.1002%2FMC.22176

21 January 2018

CHOP induces death by promoting protein synthesis and oxidation in the stressed endoplasmic reticulum

1 reference

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21 January 2018

Phosphorylation of BCL-2 regulates ER Ca2+ homeostasis and apoptosis.

1 reference

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21 January 2018

JNK phosphorylation of Bim-related members of the Bcl2 family induces Bax-dependent apoptosis

1 reference

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21 January 2018

Roles of CHOP/GADD153 in endoplasmic reticulum stress

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TRB3: a tribbles homolog that inhibits Akt/PKB activation by insulin in liver

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Glycogen synthase kinase-3beta regulates cyclin D1 proteolysis and subcellular localization

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BCR/ABL regulates expression of the cyclin-dependent kinase inhibitor p27Kip1 through the phosphatidylinositol 3-Kinase/AKT pathway

1 reference

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21 January 2018

Cytoplasmic localization of p21Cip1/WAF1 by Akt-induced phosphorylation in HER-2/neu-overexpressing cells

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Impact of the 3D microenvironment on phenotype, gene expression, and EGFR inhibition of colorectal cancer cell lines

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21 January 2018

Identifiers

10.1002/MC.22176

1 reference

Europe PubMed Central

PubMed publication ID

26 December 2017

http://europepmc.org/abstract/MED/24819444

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

26 December 2017

http://europepmc.org/abstract/MED/24819444

ResearchGate publication ID

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