(Q46927529)

English

Peroxisome proliferator-activated receptor gamma up-regulates the Bcl-2 anti-apoptotic protein in neurons and induces mitochondrial stabilization and protection against oxidative stress and apoptosis.

scientific article published on 25 October 2007

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scholarly article

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Europe PubMed Central

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9 January 2020

Peroxisome proliferator-activated receptor gamma up-regulates the Bcl-2 anti-apoptotic protein in neurons and induces mitochondrial stabilization and protection against oxidative stress and apoptosis (English)

1 reference

Europe PubMed Central

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9 January 2020

apoptotic process

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based on heuristic

inferred from title

3

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9 January 2020

Rodrigo A Fuentealba

5

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9 January 2020

author name string

Karen Fuenzalida

1

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9 January 2020

Rodrigo Quintanilla

2

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9 January 2020

Daniela Piderit

4

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9 January 2020

Gabriela Martinez

6

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9 January 2020

Nibaldo C Inestrosa

7

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9 January 2020

Miguel Bronfman

8

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9 January 2020

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publication date

25 October 2007

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9 January 2020

Journal of Biological Chemistry

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9 January 2020

282

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9 January 2020

51

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9 January 2020

37006-37015

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9 January 2020

Roles of PPARs in health and disease.

1 reference

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21 January 2018

The role of insulin resistance in the pathogenesis of Alzheimer's disease: implications for treatment

1 reference

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21 January 2018

Peroxisome proliferator-activated receptor-gamma agonist extends survival in transgenic mouse model of amyotrophic lateral sclerosis

1 reference

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21 January 2018

Insulin resistance, inflammation, and cognition in Alzheimer's Disease: lessons for multiple sclerosis

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21 January 2018

Anti-inflammatory actions of peroxisome proliferator-activated receptor gamma agonists in Alzheimer's disease

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21 January 2018

Therapeutic Potential of Peroxisome Proliferator-Activated Receptor Agonists for Neurological Disease

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21 January 2018

Peroxisome proliferator-activated receptor gamma is expressed in hippocampal neurons and its activation prevents beta-amyloid neurodegeneration: role of Wnt signaling.

1 reference

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21 January 2018

Rosiglitazone protects human neuroblastoma SH-SY5Y cells against acetaldehyde-induced cytotoxicity.

1 reference

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21 January 2018

Peroxisome proliferator-activated receptor gamma is a novel target of the nerve growth factor signaling pathway in PC12 cells.

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21 January 2018

Selectivity in neurotrophin signaling: theme and variations

1 reference

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21 January 2018

Neurotrophins and their receptors: signaling trios in complex biological systems.

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21 January 2018

The nerve growth factor 35 years later

1 reference

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21 January 2018

Cell death during development of the nervous system

1 reference

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21 January 2018

Severe sensory and sympathetic neuropathies in mice carrying a disrupted Trk/NGF receptor gene.

1 reference

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21 January 2018

Neurotrophin signal transduction in the nervous system

1 reference

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21 January 2018

The Bcl2 family: regulators of the cellular life-or-death switch

1 reference

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21 January 2018

Inhibition of mitochondrial neural cell death pathways by protein transduction of Bcl-2 family proteins

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M700447200

21 January 2018

Activation of the Bcl-2 promoter by nerve growth factor is mediated by the p42/p44 MAPK cascade

1 reference

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21 January 2018

Specificity of receptor tyrosine kinase signaling: transient versus sustained extracellular signal-regulated kinase activation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M700447200

21 January 2018

Thiazolidinedione activation of peroxisome proliferator-activated receptor gamma can enhance mitochondrial potential and promote cell survival.

1 reference

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21 January 2018

Establishment of a noradrenergic clonal line of rat adrenal pheochromocytoma cells which respond to nerve growth factor

1 reference

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21 January 2018

Gene transfer and molecular cloning of the rat nerve growth factor receptor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M700447200

21 January 2018

The trk Proto-Oncogene Product: a Signal Transducing Receptor for Nerve Growth Factor

1 reference

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21 January 2018

The invulnerability of adult neurons: a critical role for p73.

1 reference

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21 January 2018

PPAR γ activators induce growth arrest and process extension in B12 oligodendrocyte‐like cells and terminal differentiation of cultured oligodendrocytes

1 reference

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21 January 2018

Mitochondria in health and disease: perspectives on a new mitochondrial biology

1 reference

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21 January 2018

Oxidative stress and upregulation of mitochondrial biogenesis genes in mitochondrial DNA-depleted HeLa cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M700447200

21 January 2018

Death of sensory ganglion neurons after acute withdrawal of nerve growth factor in dissociated cell cultures.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M700447200

21 January 2018

Inactivation of bcl-2 results in progressive degeneration of motoneurons, sympathetic and sensory neurons during early postnatal development

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M700447200

21 January 2018

Apoptosis in the nervous system

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M700447200

21 January 2018

Troglitazone, an antidiabetic agent, inhibits cholesterol biosynthesis through a mechanism independent of peroxisome proliferator-activated receptor-gamma

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M700447200

21 January 2018

Anti-inflammatory cyclopentenone prostaglandins are direct inhibitors of IkappaB kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M700447200

21 January 2018

The role of PPAR-gamma in macrophage differentiation and cholesterol uptake.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M700447200

21 January 2018

Inhibition of phosphoenolpyruvate carboxykinase (PEPCK) gene expression by troglitazone: a peroxisome proliferator-activated receptor-gamma (PPARgamma)-independent, antioxidant-related mechanism

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M700447200

21 January 2018

Ageing and neuronal vulnerability

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M700447200

21 January 2018

Dependence of peroxisome proliferator-activated receptor ligand-induced mitogen-activated protein kinase signaling on epidermal growth factor receptor transactivation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M700447200

21 January 2018

Insulin signaling in the central nervous system: learning to survive

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M700447200

21 January 2018

Unravelling the activation mechanisms of protein kinase B/Akt

1 reference

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21 January 2018

Targeting programmed cell death in neurodegenerative diseases

1 reference

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21 January 2018

Troglitazone inhibits both post-glutamate neurotoxicity and low-potassium-induced apoptosis in cerebellar granule neurons

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M700447200

21 January 2018

Peroxisome-proliferator-activated receptor-gamma (PPARgamma) activation protects neurons from NMDA excitotoxicity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M700447200

21 January 2018

Neuroprotective effects of PPARgamma agonists against oxidative insults in HT-22 cells

1 reference

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21 January 2018

Role of nuclear receptors in lung tumourigenesis

1 reference

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21 January 2018

The nuclear receptor PPAR gamma is expressed by mouse T lymphocytes and PPAR gamma agonists induce apoptosis

1 reference

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21 January 2018

Peroxisome proliferator activator receptor-gamma agonists and 15-deoxy-Delta(12,14)(12,14)-PGJ(2) induce apoptosis in normal and malignant B-lineage cells

1 reference

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21 January 2018

Degradation of the peroxisome proliferator-activated receptor gamma is linked to ligand-dependent activation

1 reference

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21 January 2018

Troglitazone, a peroxisome proliferator-activated receptor gamma (PPAR gamma ) ligand, selectively induces the early growth response-1 gene independently of PPAR gamma. A novel mechanism for its anti-tumorigenic activity.

1 reference

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21 January 2018

Transgenic murine cortical neurons expressing human Bcl-2 exhibit increased resistance to amyloid beta-peptide neurotoxicity

1 reference

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21 January 2018

Bcl-2 protects against Abeta(25-35)-induced oxidative PC12 cell death by potentiation of antioxidant capacity

1 reference

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21 January 2018

Small interfering RNA targeting bcl-2 sensitizes malignant melanoma

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21 January 2018

Bcl-2 siRNA induced apoptosis and increased sensitivity to 5-fluorouracil and HCPT in HepG2 cells

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21 January 2018

Cell survival promoted by the Ras-MAPK signaling pathway by transcription-dependent and -independent mechanisms

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21 January 2018

Phosphorylation of PPARγ via active ERK1/2 leads to its physical association with p65 and inhibition of NF‐κβ

1 reference

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21 January 2018

Antitumorigenic effect of Wnt 7a and Fzd 9 in non-small cell lung cancer cells is mediated through ERK-5-dependent activation of peroxisome proliferator-activated receptor gamma

1 reference

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21 January 2018

Activation of cerebral peroxisome proliferator-activated receptors gamma promotes neuroprotection by attenuation of neuronal cyclooxygenase-2 overexpression after focal cerebral ischemia in rats.

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21 January 2018

Angiotensin II induces peroxisome proliferator-activated receptor gamma in PC12W cells via angiotensin type 2 receptor activation

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21 January 2018

Activation of Trk neurotrophin receptors in the absence of neurotrophins

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21 January 2018

Identifiers

10.1074/JBC.M700447200

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17965419%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17965419%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

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