(Q46947497)

26 December 2017

title

Targeting Hsp90 by 17-AAG in leukemia cells: mechanisms for synergistic and antagonistic drug combinations with arsenic trioxide and Ara-C. (English)

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26 December 2017

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Pelicano H

1

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26 December 2017

Carew JS

2

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26 December 2017

McQueen TJ

3

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26 December 2017

Andreeff M

4

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26 December 2017

Plunkett W

5

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26 December 2017

Keating MJ

6

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26 December 2017

Huang P

7

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26 December 2017

publication date

1 April 2006

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26 December 2017

published in

Leukemia

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26 December 2017

volume

20

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26 December 2017

issue

4

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26 December 2017

page(s)

610-619

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26 December 2017

Hsp90: a specialized but essential protein-folding tool

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The benzoquinone ansamycin 17-allylamino-17-demethoxygeldanamycin binds to HSP90 and shares important biologic activities with geldanamycin

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Co-treatment with As2O3 enhances selective cytotoxic effects of STI-571 against Brc-Abl-positive acute leukemia cells

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Involvement of reactive oxygen species and caspase 3 activation in arsenite-induced apoptosis

21 January 2018

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Apoptosis induced by arsenic trioxide in leukemia U937 cells is dependent on activation of p38, inactivation of ERK and the Ca2+-dependent production of superoxide

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Phosphoinositide 3-kinase/Akt involvement in arsenic trioxide resistance of human leukemia cells

21 January 2018

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A sustained activation of PI3K/NF-kappaB pathway is critical for the survival of chronic lymphocytic leukemia B cells.

21 January 2018

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The Mechanism of Action of Inhibitors of DNA Synthesis

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21 January 2018

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21 January 2018

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Hsp90 inhibition depletes Chk1 and sensitizes tumor cells to replication stress

21 January 2018

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Phase I trial of 17-allylamino-17-demethoxygeldanamycin in patients with advanced cancer

21 January 2018

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inferred from DOI database lookup

7 January 2021

based on heuristic

Arsenite induces apoptosis in Chinese hamster ovary cells by generation of reactive oxygen species

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404140

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/SJ.LEU.2404140

1 reference

26 December 2017

1 reference

26 December 2017