(Q40382560)

20 September 2017

title

Phosphoinositide 3-kinase/Akt inhibition increases arsenic trioxide-induced apoptosis of acute promyelocytic and T-cell leukaemias (English)

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20 September 2017

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7

Giovanni Martinelli

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20 September 2017

8

Michele Baccarani

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20 September 2017

6

Tiziana Grafone

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20 September 2017

2

Pier Luigi Tazzari

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20 September 2017

Giovanna Tabellini

1

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20 September 2017

Roberta Bortul

3

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20 September 2017

Camilla Evangelisti

4

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20 September 2017

Anna Maria Billi

5

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20 September 2017

Alberto M Martelli

9

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20 September 2017

language of work or name

English

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publication date

1 September 2005

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British Journal of Haematology

20 September 2017

published in

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20 September 2017

volume

130

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20 September 2017

issue

5

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20 September 2017

page(s)

716-725

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New therapeutic approaches for adult T-cell leukaemia

20 September 2017

cites work

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https://api.crossref.org/works/10.1111%2FJ.1365-2141.2005.05679.X

Deguelin, A PI3K/AKT inhibitor, enhances chemosensitivity of leukaemia cells with an active PI3K/AKT pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2005.05679.X

Advances in protein kinase B signalling: AKTion on multiple fronts

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2005.05679.X

Specific inhibition of gene expression by small double-stranded RNAs in invertebrate and vertebrate systems

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2005.05679.X

The phosphoinositide 3-kinase/Akt pathway regulates cell cycle progression of HL60 human leukemia cells through cytoplasmic relocalization of the cyclin-dependent kinase inhibitor p27(Kip1) and control of cyclin D1 expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2005.05679.X

Serine/threonine protein kinases and apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2005.05679.X

Arsenic trioxide: new clinical experience with an old medication in hematologic malignancies

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2005.05679.X

Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2005.05679.X

The potential of arsenic trioxide in the treatment of malignant disease: past, present, and future

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2005.05679.X

Structure, regulation and function of PKB/AKT--a major therapeutic target

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2005.05679.X

Arsenic trioxide therapy for relapsed acute promyelocytic leukemia: an useful salvage therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2005.05679.X

Single-step procedure for labeling DNA strand breaks with fluorescein- or BODIPY-conjugated deoxynucleotides: detection of apoptosis and bromodeoxyuridine incorporation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2005.05679.X

Arsenic trioxide (ATO) and MEK1 inhibition synergize to induce apoptosis in acute promyelocytic leukemia cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2005.05679.X

Map kinase signaling pathways and hematologic malignancies

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2005.05679.X

Acute promyelocytic leukemia: PML/RARalpha and the leukemic stem cell.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2005.05679.X

Pharmacologic inhibitors of PI3K/Akt potentiate the apoptotic action of the antileukemic drug arsenic trioxide via glutathione depletion and increased peroxide accumulation in myeloid leukemia cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2005.05679.X

In vitro and in vivo effectiveness of arsenic trioxide against murine T-cell prolymphocytic leukaemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2005.05679.X

Dual effects of arsenic trioxide (As2O3) on non-acute promyelocytic leukaemia myeloid cell lines: induction of apoptosis and inhibition of proliferation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2005.05679.X

siRNA therapeutics: big potential from small RNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2005.05679.X

Phosphoinositide 3-kinase/Akt involvement in arsenic trioxide resistance of human leukemia cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2005.05679.X

Detection of serine 473 phosphorylated Akt in acute myeloid leukaemia blasts by flow cytometry

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2005.05679.X

Inhibition of phosphatidylinositol 3'-kinase induces preferentially killing of PTEN-null T leukemias through AKT pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2005.05679.X

A novel assay for apoptosis. Flow cytometric detection of phosphatidylserine expression on early apoptotic cells using fluorescein labelled Annexin V

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2005.05679.X

Mitogen-activated protein kinases in apoptosis regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2005.05679.X

Activation of the PI3K/Akt pathway and chemotherapeutic resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2005.05679.X

Survival of acute myeloid leukemia cells requires PI3 kinase activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2005.05679.X

Inhibition of phosphatidylinositol 3-kinase dephosphorylates BAD and promotes apoptosis in myeloid leukemias

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2005.05679.X

How acute promyelocytic leukaemia revived arsenic

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2005.05679.X

10.1111/J.1365-2141.2005.05679.X

21 January 2018

Identifiers

DOI

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20 September 2017

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