(Q46959473)

26 December 2017

title

C-440T/T-331C polymorphisms in the UGT1A9 gene affect the pharmacokinetics of mycophenolic acid in kidney transplantation (English)

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26 December 2017

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7

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26 December 2017

Monica Cortinovis

5

Monica Cortinovis

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26 December 2017

Dario Cattaneo

8

Dario Cattaneo

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26 December 2017

Norberto Perico

3

Norberto Perico

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26 December 2017

Eliana Gotti

6

Eliana Gotti

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26 December 2017

Sara Baldelli

1

Sara Baldelli

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26 December 2017

Simona Merlini

2

Simona Merlini

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26 December 2017

Annalisa Nicastri

4

Annalisa Nicastri

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26 December 2017

publication date

1 September 2007

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26 December 2017

published in

Pharmacogenomics

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26 December 2017

volume

8

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26 December 2017

issue

9

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26 December 2017

page(s)

1127-1141

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26 December 2017

Mycophenolates in transplantation

cites work

1 reference

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Glucuronide and glucoside conjugation of mycophenolic acid by human liver, kidney and intestinal microsomes

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Comparison of the effects of tacrolimus and cyclosporine on the pharmacokinetics of mycophenolic acid

21 January 2018

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Therapeutic drug monitoring of mycophenolate mofetil in transplantation

21 January 2018

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Pharmacokinetics help optimizing mycophenolate mofetil dosing in kidney transplant patients

21 January 2018

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Explaining variability in mycophenolic acid exposure to optimize mycophenolate mofetil dosing: a population pharmacokinetic meta-analysis of mycophenolic acid in renal transplant recipients.

21 January 2018

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From pharmacokinetics to pharmacogenomics: a new approach to tailor immunosuppressive therapy

21 January 2018

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Clinical pharmacogenetics of immunosuppressive drugs in organ transplantation.

21 January 2018

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Effects of genetic polymorphisms of CYP3A4, CYP3A5 and MDR1 on cyclosporine pharmacokinetics after renal transplantation.

21 January 2018

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Genetic polymorphisms of ATP-binding cassette transporters ABCB1 and ABCG2: therapeutic implications

21 January 2018

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Identification of uridine diphosphate glucuronosyltransferases involved in the metabolism and clearance of mycophenolic acid

21 January 2018

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The main role of UGT1A9 in the hepatic metabolism of mycophenolic acid and the effects of naturally occurring variants

21 January 2018

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Influence of nonsynonymous polymorphisms of UGT1A8 and UGT2B7 metabolizing enzymes on the formation of phenolic and acyl glucuronides of mycophenolic acid

21 January 2018

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Identification of the UDP-glucuronosyltransferase isoforms involved in mycophenolic acid phase II metabolism.

21 January 2018

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Identification of common polymorphisms in the promoter of the UGT1A9 gene: evidence that UGT1A9 protein and activity levels are strongly genetically controlled in the liver.

21 January 2018

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Novel functional polymorphisms in the UGT1A7 and UGT1A9 glucuronidating enzymes in Caucasian and African-American subjects and their impact on the metabolism of 7-ethyl-10-hydroxycamptothecin and flavopiridol anticancer drugs

21 January 2018

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Functional Characterization of Human UDP-Glucuronosyltransferase 1A9 Variant, D256N, Found in Japanese Cancer Patients

21 January 2018

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Characterization of common UGT1A8, UGT1A9, and UGT2B7 variants with different capacities to inactivate mutagenic 4-hydroxylated metabolites of estradiol and estrone.

21 January 2018

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Genetic polymorphism of UDP-glucuronosyltransferase 2B7 (UGT2B7) at amino acid 268: ethnic diversity of alleles and potential clinical significance

21 January 2018

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Single nucleotide polymorphisms in multidrug resistance associated protein 2 (MRP2/ABCC2): its impact on drug disposition

21 January 2018

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The impact of uridine diphosphate-glucuronosyltransferase 1A9 (UGT1A9) gene promoter region single-nucleotide polymorphisms T-275A and C-2152T on early mycophenolic acid dose-interval exposure in de novo renal allograft recipients

21 January 2018

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Simultaneous determination of everolimus and cyclosporine concentrations by HPLC with ultraviolet detection

21 January 2018

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Hepatic expression of the UGT1A9 gene is governed by hepatocyte nuclear factor 4alpha

21 January 2018

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https://api.crossref.org/works/10.2217%2F14622416.8.9.1127

Therapeutic drug monitoring of mycophenolic acid in solid organ transplant patients treated with mycophenolate mofetil: review of the literature.

21 January 2018

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https://api.crossref.org/works/10.2217%2F14622416.8.9.1127

Glucocorticoids interfere with mycophenolate mofetil bioavailability in kidney transplantation

21 January 2018

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Clinical pharmacokinetics and pharmacodynamics of mycophenolate in solid organ transplant recipients

21 January 2018

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Long-term changes in mycophenolic acid exposure in combination with tacrolimus and corticosteroids are dose dependent and not reflected by trough plasma concentration: a prospective study in 100 de novo renal allograft recipients

21 January 2018

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Mycophenolic acid 12-h trough level monitoring in renal transplantation: association with acute rejection and toxicity

21 January 2018

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https://api.crossref.org/works/10.2217%2F14622416.8.9.1127

Pharmacokinetics of mycophenolic acid in renal insufficiency

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.8.9.1127

Pharmacokinetics of mycophenolate mofetil in kidney transplant patients with renal insufficiency

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.8.9.1127

Cyclosporin A, but not tacrolimus, inhibits the biliary excretion of mycophenolic acid glucuronide possibly mediated by multidrug resistance-associated protein 2 in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.8.9.1127

Cyclosporine interacts with mycophenolic acid by inhibiting the multidrug resistance-associated protein 2.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.8.9.1127

Polymorphism of the ABC transporter genes, MDR1, MRP1 and MRP2/cMOAT, in healthy Japanese subjects

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.8.9.1127

Pharmacogenetic profiling across the irinotecan pathway in Asian patients with cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.8.9.1127

Influence of co-medication with sirolimus or cyclosporine on mycophenolic acid pharmacokinetics in kidney transplantation

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.8.9.1127

Characterization of the cellular localization, expression level, and function of SNP variants of MRP2/ABCC2.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.8.9.1127

10.2217/14622416.8.9.1127

21 January 2018

Identifiers

DOI

1 reference

26 December 2017

1 reference

26 December 2017