(Q46986547)

27 December 2017

title

Interdomain conformational changes in Akt activation revealed by chemical cross-linking and tandem mass spectrometry (English)

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27 December 2017

author name string

Bill X Huang

series ordinal

1

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27 December 2017

Hee-Yong Kim

series ordinal

2

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27 December 2017

publication date

9 March 2006

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27 December 2017

Molecular & Cellular Proteomics

published in

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27 December 2017

volume

5

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27 December 2017

page(s)

1045-1053

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27 December 2017

issue

6

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27 December 2017

Ten years of protein kinase B signalling: a hard Akt to follow

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1 reference

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A retroviral oncogene, akt, encoding a serine-threonine kinase containing an SH2-like region

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Mechanism of activation and function of protein kinase B.

21 January 2018

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High-resolution structure of the pleckstrin homology domain of protein kinase b/akt bound to phosphatidylinositol (3,4,5)-trisphosphate

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Dual role of phosphatidylinositol-3,4,5-trisphosphate in the activation of protein kinase B

21 January 2018

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Role of translocation in the activation and function of protein kinase B

21 January 2018

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Akt activation by growth factors is a multiple-step process: the role of the PH domain

21 January 2018

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Akt/PKB localisation and 3' phosphoinositide generation at sites of epithelial cell-matrix and cell-cell interaction

21 January 2018

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Molecular mechanism for the regulation of protein kinase B/Akt by hydrophobic motif phosphorylation

21 January 2018

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Cellular survival: a play in three Akts

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Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery

21 January 2018

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Binding of phosphatidylinositol 3,4,5-trisphosphate to the pleckstrin homology domain of protein kinase B induces a conformational change

21 January 2018

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Crystal structure of an inactive Akt2 kinase domain

21 January 2018

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Solution structure and backbone dynamics of the pleckstrin homology domain of the human protein kinase B (PKB/Akt). Interaction with inositol phosphates

21 January 2018

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Monitoring conformational changes of proteins in cells by fluorescence lifetime imaging microscopy

21 January 2018

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High throughput protein fold identification by using experimental constraints derived from intramolecular cross-links and mass spectrometry.

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Chemical cross-linking and mass spectrometry for protein structural modeling.

21 January 2018

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Probing conformational changes of human serum albumin due to unsaturated fatty acid binding by chemical cross-linking and mass spectrometry

21 January 2018

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A three-dimensional molecular model of lipid-free apolipoprotein A-I determined by cross-linking/mass spectrometry and sequence threading.

21 January 2018

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Chemical cross-linking with thiol-cleavable reagents combined with differential mass spectrometric peptide mapping--a novel approach to assess intermolecular protein contacts

21 January 2018

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21 January 2018

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Cross-linking phosphatidylinositol-specific phospholipase C traps two activating phosphatidylcholine molecules on the enzyme

21 January 2018

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Mapping protein-protein interactions between MutL and MutH by cross-linking

21 January 2018

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Unraveling the interface of signal recognition particle and its receptor by using chemical cross-linking and tandem mass spectrometry

21 January 2018

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Probing three-dimensional structure of bovine serum albumin by chemical cross-linking and mass spectrometry

21 January 2018

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Proteolytic 18O labeling for comparative proteomics: model studies with two serotypes of adenovirus

21 January 2018

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Characterization of a 3-phosphoinositide-dependent protein kinase which phosphorylates and activates protein kinase Balpha

21 January 2018

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MS2Assign, automated assignment and nomenclature of tandem mass spectra of chemically crosslinked peptides.

21 January 2018

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Characterization of an Antagonist Interleukin-6 Dimer by Stable Isotope Labeling, Cross-linking, and Mass Spectrometry

21 January 2018

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10.1074/MCP.M600026-MCP200

21 January 2018

Identifiers

DOI

1 reference

27 December 2017

PubMed ID

16531397

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27 December 2017