(Q47069565)

http://europepmc.org/abstract/MED/24643799

4 January 2018

title

Huwe1-mediated ubiquitylation of dishevelled defines a negative feedback loop in the Wnt signaling pathway (English)

1 reference

http://europepmc.org/abstract/MED/24643799

4 January 2018

1 reference

1

1 reference

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10 June 2020

Ondrej Bernatik

3

1 reference

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10 June 2020

Bethan Lloyd-Lewis

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24643799%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

Katja Seipel

5

1 reference

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10 June 2020

Zbyněk Zdráhal

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24643799%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

Trevor Dale

9

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24643799%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

Vítězslav Bryja

11

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10 June 2020

author name string

Ranjani S Ganji

2

1 reference

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10 June 2020

Kateřina Šedová

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24643799%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

Vishnu M Dhople

8

1 reference

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10 June 2020

Hendrik C Korswagen

10

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10 June 2020

publication date

18 March 2014

1 reference

http://europepmc.org/abstract/MED/24643799

4 January 2018

published in

Science Signaling

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24643799%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

volume

7

1 reference

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10 June 2020

issue

317

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10 June 2020

page(s)

ra26

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24643799%20AND%20SRC:MED&resulttype=core&format=json

Wnt/beta-catenin signaling: components, mechanisms, and diseases

10 June 2020

cites work

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2004985

Wnt induces LRP6 signalosomes and promotes dishevelled-dependent LRP6 phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2004985

Sequential activation and inactivation of Dishevelled in the Wnt/beta-catenin pathway by casein kinases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2004985

RNA helicase DDX3 is a regulatory subunit of casein kinase 1 in Wnt-β-catenin signaling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2004985

The DIX domain of Dishevelled confers Wnt signaling by dynamic polymerization

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2004985

The Wnt signalling effector Dishevelled forms dynamic protein assemblies rather than stable associations with cytoplasmic vesicles.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2004985

The KLHL12-Cullin-3 ubiquitin ligase negatively regulates the Wnt-beta-catenin pathway by targeting Dishevelled for degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2004985

Loss of the tumor suppressor CYLD enhances Wnt/beta-catenin signaling through K63-linked ubiquitination of Dvl

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2004985

The E3 ubiquitin ligase ITCH negatively regulates canonical Wnt signaling by targeting dishevelled protein

21 January 2018

1 reference

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Nonproteolytic functions of ubiquitin in cell signaling

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCISIGNAL.2004985

Dishevelled: The hub of Wnt signaling

21 January 2018

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Migration of neuronal cells along the anterior-posterior body axis of C. elegans: Wnts are in control

21 January 2018

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Inhibition of late endosomal maturation restores Wnt secretion in Caenorhabditis elegans vps-29 retromer mutants

21 January 2018

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A SNX3-dependent retromer pathway mediates retrograde transport of the Wnt sorting receptor Wntless and is required for Wnt secretion

21 January 2018

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Imaging individual mRNA molecules using multiple singly labeled probes

21 January 2018

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Wnt signal from multiple tissues and lin-3/EGF signal from the gonad maintain vulval precursor cell competence in Caenorhabditis elegans

21 January 2018

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Activation of Wnt signaling bypasses the requirement for RTK/Ras signaling during C. elegans vulval induction

21 January 2018

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A useful approach to identify novel small-molecule inhibitors of Wnt-dependent transcription

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCISIGNAL.2004985

Truncated mutants of the putative Wnt receptor LRP6/Arrow can stabilize beta-catenin independently of Frizzled proteins

21 January 2018

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Activation of beta-catenin-Tcf signaling in colon cancer by mutations in beta-catenin or APC

21 January 2018

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The ubiquitin ligase HectH9 regulates transcriptional activation by Myc and is essential for tumor cell proliferation

21 January 2018

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Regulation of casein kinase I epsilon activity by Wnt signaling

21 January 2018

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ARF-BP1/Mule is a critical mediator of the ARF tumor suppressor

21 January 2018

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The EEL-1 ubiquitin ligase promotes DNA damage-induced germ cell apoptosis in C. elegans

21 January 2018

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The N-Myc-DLL3 cascade is suppressed by the ubiquitin ligase Huwe1 to inhibit proliferation and promote neurogenesis in the developing brain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2004985

The HECT-domain ubiquitin ligase Huwe1 controls neural differentiation and proliferation by destabilizing the N-Myc oncoprotein

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2004985

Mule/ARF-BP1, a BH3-only E3 ubiquitin ligase, catalyzes the polyubiquitination of Mcl-1 and regulates apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2004985

Differential recruitment of Dishevelled provides signaling specificity in the planar cell polarity and Wingless signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2004985

Dishevelled activates JNK and discriminates between JNK pathways in planar polarity and wingless signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2004985

Parkin mediates nonclassical, proteasomal-independent ubiquitination of synphilin-1: implications for Lewy body formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2004985

Dynamic recruitment of axin by Dishevelled protein assemblies

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2004985

Deubiquitination of Dishevelled by Usp14 is required for Wnt signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2004985

NEDL1, a novel ubiquitin-protein isopeptide ligase for dishevelled-1, targets mutant superoxide dismutase-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2004985

Insertional mutagenesis identifies multiple networks of cooperating genes driving intestinal tumorigenesis

21 January 2018

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COSMIC: mining complete cancer genomes in the Catalogue of Somatic Mutations in Cancer

21 January 2018

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Toward improving Caenorhabditis elegans phenome mapping with an ORFeome-based RNAi library

21 January 2018

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Systematic functional analysis of the Caenorhabditis elegans genome using RNAi

21 January 2018

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21 January 2018

1 reference

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Characterization of mouse dishevelled (Dvl) proteins in Wnt/Wingless signaling pathway

21 January 2018

1 reference

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Breast cancer-specific mutations in CK1epsilon inhibit Wnt/beta-catenin and activate the Wnt/Rac1/JNK and NFAT pathways to decrease cell adhesion and promote cell migration.

21 January 2018

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A mechanism for Wnt coreceptor activation

21 January 2018

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Zebrafish prickle, a modulator of noncanonical Wnt/Fz signaling, regulates gastrulation movements.

21 January 2018

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Protein structure prediction on the Web: a case study using the Phyre server

21 January 2018

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21 January 2018

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21 January 2018

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24643799%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

1 reference