(Q47095767)

English

Biological characterization of the hygrobafilomycin antibiotic JBIR-100 and bioinformatic insights into the hygrolide family of natural products.

scientific article published on 14 May 2016

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scholarly article

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3 April 2020

Biological characterization of the hygrobafilomycin antibiotic JBIR-100 and bioinformatic insights into the hygrolide family of natural products (English)

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3 April 2020

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natural product

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Evelyn M Molloy

1

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3 April 2020

Jonathan I Tietz

2

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3 April 2020

Patricia M Blair

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3 April 2020

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Douglas A Mitchell

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3 April 2020

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14 May 2016

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3 April 2020

Bioorganic & Medicinal Chemistry

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3 April 2020

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3 April 2020

6276-6290

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3 April 2020

Bafilomycin A1 inhibits the growth and metastatic potential of the BEL-7402 liver cancer and HO-8910 ovarian cancer cell lines and induces alterations in their microRNA expression

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Bafilomycin A1 targets both autophagy and apoptosis pathways in pediatric B-cell acute lymphoblastic leukemia

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Suppression of influenza A virus replication in human lung epithelial cells by noncytotoxic concentrations bafilomycin A1.

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23 May 2018

Organization and characterization of a biosynthetic gene cluster for bafilomycin from Streptomyces griseus DSM 2608.

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23 May 2018

Characterization of the bafilomycin biosynthetic gene cluster from Streptomyces lohii

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23 May 2018

Ribosomally synthesized and post-translationally modified peptide natural products: overview and recommendations for a universal nomenclature

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23 May 2018

Identification of the biosynthetic gene cluster for the antibiotic polyketide L-155,175 in Streptomyces hygroscopicus

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V-ATPases in osteoclasts: structure, function and potential inhibitors of bone resorption

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Intracellular proton pumps as targets in chemotherapy: V-ATPases and cancer

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23 May 2018

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Bafilomycin K, a new antifungal macrolide from Streptomyces flavotricini Y12-26.

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Challenges of antibacterial discovery

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23 May 2018

Macrolides of the bafilomycin family produced by Streptomyces sp. CS.

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23 May 2018

Structural and functional analysis of A-type ketoreductases from the amphotericin modular polyketide synthase

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23 May 2018

Hygrobafilomycin, a cytotoxic and antifungal macrolide bearing a unique monoalkylmaleic anhydride moiety, from Streptomyces varsoviensis

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23 May 2018

Low-dose bafilomycin attenuates neuronal cell death associated with autophagy-lysosome pathway dysfunction.

1 reference

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23 May 2018

A three enzyme pathway for 2-amino-3-hydroxycyclopent-2-enone formation and incorporation in natural product biosynthesis

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23 May 2018

Inhibition of Plasmodium falciparum pH regulation by small molecule indole derivatives results in rapid parasite death

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23 May 2018

Bafilomycins produced in culture by Streptomyces spp. isolated from marine habitats are potent inhibitors of autophagy

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23 May 2018

The biosynthetic logic of polyketide diversity

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23 May 2018

Vacuolar ATPases: rotary proton pumps in physiology and pathophysiology

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23 May 2018

A tylosin ketoreductase reveals how chirality is determined in polyketides

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23 May 2018

Bactericidal agents in the treatment of MRSA infections--the potential role of daptomycin

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Autophagy, bafilomycin and cell death: the "a-B-cs" of plecomacrolide-induced neuroprotection

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23 May 2018

Effect of bafilomycin A1 and nocodazole on endocytic transport in HeLa cells: implications for viral uncoating and infection

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23 May 2018

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23 May 2018

Inhibitory effect of bafilomycin A1, a specific inhibitor of vacuolar-type proton pump, on the growth of influenza A and B viruses in MDCK cells

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23 May 2018

Bafilomycin A1, a specific inhibitor of vacuolar-type H(+)-ATPase, blocks lysosomal cholesterol trafficking in macrophages.

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23 May 2018

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Inhibition of the acidification of endosomes and lysosomes by the antibiotic concanamycin B in macrophage J774.

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23 May 2018

Inhibition of the accumulation of lipid droplets in macrophage J774 by bafilomycin B1 and destruxin E.

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A new 16-membered tetraene macrolide JBIR-100 from a newly identified Streptomyces species.

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15 August 2018

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15 August 2018

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15 August 2018

A model of structure and catalysis for ketoreductase domains in modular polyketide synthases

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15 August 2018

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15 August 2018

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15 August 2018

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15 August 2018

PC-766B, a new macrolide antibiotic produced by Nocardia brasiliensis. II. Isolation, physico-chemical properties and structure elucidation.

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15 August 2018

Isolation and structural elucidation of new 18-membered macrolide antibiotics, viranamycins A and B

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15 August 2018

Reveromycins Revealed: New polyketide spiroketals from Australian marine-derived and terrestrial Streptomyces spp. A case of natural products vs. artifacts

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29 September 2018

Accurate flow cytometric membrane potential measurement in bacteria using diethyloxacarbocyanine and a ratiometric technique

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12 December 2020

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The isolation and structures of hygrolidin amide and defumarylhygrolidin

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12 December 2020

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On the Biosynthetic Origin of Methoxymalonyl-Acyl Carrier Protein, the Substrate for Incorporation of “Glycolate” Units into Ansamitocin and Soraphen A

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12 December 2020

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Reveromycin A, a new antibiotic which inhibits the mitogenic activity of epidermal growth factor

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12 December 2020

based on heuristic

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Determination of the Absolute Configuration of Peptide Natural Products by Using Stable Isotope Labeling and Mass Spectrometry

1 reference

https://pubmed.ncbi.nlm.nih.gov/27234886

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ro 09-1679, a novel thrombin inhibitor

1 reference

https://pubmed.ncbi.nlm.nih.gov/27234886

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The structure of virustomycin A

1 reference

https://pubmed.ncbi.nlm.nih.gov/27234886

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

L-155,175: a new antiparasitic macrolide. Fermentation, isolation and structure

1 reference

https://pubmed.ncbi.nlm.nih.gov/27234886

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Metabolic products of microorganisms. 224. Bafilomycins, a new group of macrolide antibiotics. Production, isolation, chemical structure and biological activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/27234886

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fumimycin: A Peptide Deformylase Inhibitor with an Unusual Skeleton Produced byAspergillusfumisynnematus

1 reference

https://pubmed.ncbi.nlm.nih.gov/27234886

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1016/J.BMC.2016.05.021

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27234886%20AND%20SRC:MED&resulttype=core&format=json

3 April 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27234886%20AND%20SRC:MED&resulttype=core&format=json

3 April 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27234886%20AND%20SRC:MED&resulttype=core&format=json

3 April 2020

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