(Q38258173)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25296440%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

review article

1 reference

title

Genome mining: concept and strategies for natural product discovery (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25296440%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

1 reference

Markus Nett

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25296440%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

publication date

1 January 2014

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25296440%20AND%20SRC:MED&resulttype=core&format=json

Progress in the Chemistry of Organic Natural Products

20 February 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25296440%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

volume

99

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25296440%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

page(s)

199-245

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25296440%20AND%20SRC:MED&resulttype=core&format=json

From bacterial genomes to novel antibacterial agents: discovery, characterization, and antibacterial activity of compounds that bind to HI0065 (YjeE) from Haemophilus influenzae

20 February 2020

cites work

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Genome mining for novel natural product discovery

31 March 2020

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Antibiotic research in the age of omics: from expression profiles to interspecies communication

31 March 2020

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Polyketide synthases and nonribosomal peptide synthetases: the emerging view from bacterial genomics

31 March 2020

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Strategies to unravel the function of orphan biosynthesis pathways: recent examples and future prospects

31 March 2020

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Natural products: a continuing source of novel drug leads

31 March 2020

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Renaissance in antibacterial discovery from actinomycetes

31 March 2020

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Identification, characterization and potent antitumor activity of ECO-4601, a novel peripheral benzodiazepine receptor ligand

31 March 2020

1 reference

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Daptomycin biosynthesis in Streptomyces roseosporus: cloning and analysis of the gene cluster and revision of peptide stereochemistry

31 March 2020

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Analysis of the genome sequence of the flowering plant Arabidopsis thaliana

31 March 2020

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Dozens of toxin-related genes are expressed in a nontoxic strain of the dinoflagellate Heterocapsa circularisquama

31 March 2020

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Making new molecules - evolution of pathways for novel metabolites in plants.

31 March 2020

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Clusters of genes for the biosynthesis of antibiotics: regulatory genes and overproduction of pharmaceuticals

31 March 2020

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Evolution of genome architecture

31 March 2020

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The biosynthetic logic of polyketide diversity

31 March 2020

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An unusually large multifunctional polypeptide in the erythromycin-producing polyketide synthase of Saccharopolyspora erythraea

31 March 2020

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Alteration of the substrate specificity of a modular polyketide synthase acyltransferase domain through site-specific mutations.

31 March 2020

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A novel method for accurate operon predictions in all sequenced prokaryotes

31 March 2020

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FramePlot: a new implementation of the frame analysis for predicting protein-coding regions in bacterial DNA with a high G + C content.

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-04900-7_4

Beyond ethylmalonyl-CoA: the functional role of crotonyl-CoA carboxylase/reductase homologs in expanding polyketide diversity

31 March 2020

1 reference

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Significant natural product biosynthetic potential of actinorhizal symbionts of the genus frankia, as revealed by comparative genomic and proteomic analyses.

31 March 2020

1 reference

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Biosynthesis of polyketides by trans-AT polyketide synthases

31 March 2020

1 reference

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Type II polyketide synthases: gaining a deeper insight into enzymatic teamwork

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-04900-7_4

The chalcone synthase superfamily of type III polyketide synthases

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-04900-7_4

Working outside the protein-synthesis rules: insights into non-ribosomal peptide synthesis

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-04900-7_4

Structural basis for the activation of phenylalanine in the non-ribosomal biosynthesis of gramicidin S

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-04900-7_4

The specificity-conferring code of adenylation domains in nonribosomal peptide synthetases

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-04900-7_4

Predictive, structure-based model of amino acid recognition by nonribosomal peptide synthetase adenylation domains

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-04900-7_4

Nonribosomal peptide synthesis in Schizosaccharomyces pombe and the architectures of ferrichrome-type siderophore synthetases in fungi

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-04900-7_4

Assembly-line enzymology for polyketide and nonribosomal Peptide antibiotics: logic, machinery, and mechanisms.

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-04900-7_4

Ribosomally synthesized and post-translationally modified peptide natural products: overview and recommendations for a universal nomenclature

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-04900-7_4

Patellamide A and C biosynthesis by a microcin-like pathway in Prochloron didemni, the cyanobacterial symbiont of Lissoclinum patella

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-04900-7_4

Evolution of lanthipeptide synthetases

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-04900-7_4

In silico analysis highlights the frequency and diversity of type 1 lantibiotic gene clusters in genome sequenced bacteria.

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-04900-7_4

Genes and enzymes involved in bacterial isoprenoid biosynthesis

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-04900-7_4

Terpene biosynthesis: modularity rules

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-04900-7_4

Studies on biosynthetic genes and enzymes of isoprenoids produced by actinomycetes

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-04900-7_4

Exploration and mining of the bacterial terpenome

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-04900-7_4

Bioinformatic perspectives on NRPS/PKS megasynthases: advances and challenges

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-04900-7_4

SEARCHPKS: A program for detection and analysis of polyketide synthase domains.

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-04900-7_4

NRPS-PKS: a knowledge-based resource for analysis of NRPS/PKS megasynthases

31 March 2020

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Computational approach for prediction of domain organization and substrate specificity of modular polyketide synthases

31 March 2020

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SBSPKS: structure based sequence analysis of polyketide synthases

31 March 2020

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ASMPKS: an analysis system for modular polyketide synthases

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-04900-7_4

ClustScan: an integrated program package for the semi-automatic annotation of modular biosynthetic gene clusters and in silico prediction of novel chemical structures

31 March 2020

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Automated genome mining for natural products.

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-04900-7_4

Specificity prediction of adenylation domains in nonribosomal peptide synthetases (NRPS) using transductive support vector machines (TSVMs)

31 March 2020

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https://api.crossref.org/works/10.1007%2F978-3-319-04900-7_4

NRPSpredictor2--a web server for predicting NRPS adenylation domain specificity

31 March 2020

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NRPSsp: non-ribosomal peptide synthase substrate predictor

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-04900-7_4

Classification of the adenylation and acyl-transferase activity of NRPS and PKS systems using ensembles of substrate specific hidden Markov models

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-04900-7_4

Comprehensive analysis of distinctive polyketide and nonribosomal peptide structural motifs encoded in microbial genomes.

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-04900-7_4

The natural product domain seeker NaPDoS: a phylogeny based bioinformatic tool to classify secondary metabolite gene diversity

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-04900-7_4

CLUSEAN: a computer-based framework for the automated analysis of bacterial secondary metabolite biosynthetic gene clusters

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-04900-7_4

SMURF: Genomic mapping of fungal secondary metabolite clusters

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-04900-7_4

PKMiner: a database for exploring type II polyketide synthases

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-04900-7_4

SEARCHGTr: a program for analysis of glycosyltransferases involved in glycosylation of secondary metabolites

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-04900-7_4

BAGEL: a web-based bacteriocin genome mining tool.

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-04900-7_4

BAGEL2: mining for bacteriocins in genomic data

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-04900-7_4

antiSMASH: rapid identification, annotation and analysis of secondary metabolite biosynthesis gene clusters in bacterial and fungal genome sequences

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-04900-7_4

antiSMASH 2.0--a versatile platform for genome mining of secondary metabolite producers

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-04900-7_4

Microbial genomics as a guide to drug discovery and structural elucidation: ECO-02301, a novel antifungal agent, as an example.

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-04900-7_4

Genomic analyses lead to novel secondary metabolites. Part 3. ECO-0501, a novel antibacterial of a new class.

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-04900-7_4

Isolation and identification of three new 5-alkenyl-3,3(2H)-furanones from two streptomyces species using a genomic screening approach.

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-04900-7_4

Genome sequencing reveals complex secondary metabolome in the marine actinomycete Salinispora tropica

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-04900-7_4

Exploiting the mosaic structure of trans-acyltransferase polyketide synthases for natural product discovery and pathway dissection

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-04900-7_4

Discovery of aspoquinolones A-D, prenylated quinoline-2-one alkaloids from Aspergillus nidulans, motivated by genome mining.

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-04900-7_4

The genomisotopic approach: a systematic method to isolate products of orphan biosynthetic gene clusters

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-04900-7_4

Genomics-driven discovery of taiwachelin, a lipopeptide siderophore from Cupriavidus taiwanensis

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-04900-7_4

Determination of the Absolute Configuration of Peptide Natural Products by Using Stable Isotope Labeling and Mass Spectrometry

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-04900-7_4

A mass spectrometry-guided genome mining approach for natural product peptidogenomics

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-04900-7_4

Imaging mass spectrometry and genome mining via short sequence tagging identified the anti-infective agent arylomycin in Streptomyces roseosporus

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-04900-7_4

Neutral loss fragmentation pattern based screening for arginine-rich natural products in Xenorhabdus and Photorhabdus.

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-04900-7_4

Universal chemical assay for the detection and determination of siderophores.

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-04900-7_4

Structure elucidation and biosynthesis of fuscachelins, peptide siderophores from the moderate thermophile Thermobifida fusca

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-04900-7_4

Rapid PCR amplification of minimal enediyne polyketide synthase cassettes leads to a predictive familial classification model

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-04900-7_4

A genomics-guided approach for discovering and expressing cryptic metabolic pathways.

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-04900-7_4

A colorimetric assay of lysogenic induction designed for screening potential carcinogenic and carcinostatic agents

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-04900-7_4

Bioactivity-guided genome mining reveals the lomaiviticin biosynthetic gene cluster in Salinispora tropica

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-04900-7_4

Discovery and in vitro biosynthesis of haloduracin, a two-component lantibiotic

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-04900-7_4

Identification of a novel two-peptide lantibiotic, lichenicidin, following rational genome mining for LanM proteins.

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-04900-7_4

Bacterial self-resistance to the natural proteasome inhibitor salinosporamide A.

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-04900-7_4

Big effects from small changes: possible ways to explore nature's chemical diversity.

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-04900-7_4

Farinamycin, a quinazoline from Streptomyces griseus

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-04900-7_4

Epigenome manipulation as a pathway to new natural product scaffolds and their congeners

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-04900-7_4

Intimate bacterial-fungal interaction triggers biosynthesis of archetypal polyketides in Aspergillus nidulans

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-04900-7_4

Imaging mass spectrometry and genome mining reveal highly antifungal virulence factor of mushroom soft rot pathogen

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-04900-7_4

Closthioamide: An Unprecedented Polythioamide Antibiotic from the Strictly Anaerobic Bacterium Clostridium cellulolyticum

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-04900-7_4

Formation of novel secondary metabolites by bacterial multimodular assembly lines: deviations from textbook biosynthetic logic.

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-04900-7_4

Multiple hybrid polyketide synthase/non-ribosomal peptide synthetase gene clusters in the myxobacterium Stigmatella aurantiaca

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-04900-7_4

Structure and biosynthesis of myxochromides S1-3 in Stigmatella aurantiaca: evidence for an iterative bacterial type I polyketide synthase and for module skipping in nonribosomal peptide biosynthesis

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-04900-7_4

Aurafuron A and B, new bioactive polyketides from Stigmatella aurantiaca and Archangium gephyra (Myxobacteria). Fermentation, isolation, physico-chemical properties, structure and biological activity

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-04900-7_4

Discovery of the rhizopodin biosynthetic gene cluster in Stigmatella aurantiaca Sg a15 by genome mining.

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-04900-7_4

Evolution of sensory complexity recorded in a myxobacterial genome

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-04900-7_4

The impact of genomics on the exploitation of the myxobacterial secondary metabolome

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-04900-7_4

Identification and Characterization of the Althiomycin Biosynthetic Gene Cluster in Myxococcus xanthus DK897

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-04900-7_4

Myxoprincomide: A Natural Product from Myxococcus xanthus Discovered by Comprehensive Analysis of the Secondary Metabolome

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-04900-7_4

Genomic basis for natural product biosynthetic diversity in the actinomycetes

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-04900-7_4

Coelichelin, a new peptide siderophore encoded by the Streptomyces coelicolor genome: structure prediction from the sequence of its non-ribosomal peptide synthetase

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-04900-7_4

Discovery of a new peptide natural product by Streptomyces coelicolor genome mining

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-04900-7_4

Type III polyketide synthase beta-ketoacyl-ACP starter unit and ethylmalonyl-CoA extender unit selectivity discovered by Streptomyces coelicolor genome mining

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-04900-7_4

Genome-inspired search for new antibiotics. Isolation and structure determination of new 28-membered polyketide macrolactones, halstoctacosanolides A and B, from Streptomyces halstedii HC34

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-04900-7_4

The complete biosynthetic gene cluster of the 28-membered polyketide macrolactones, halstoctacosanolides, from Streptomyces halstedii HC34.

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-04900-7_4

Structural and functional characterization of three polyketide synthase gene clusters in Bacillus amyloliquefaciens FZB 42.

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-04900-7_4

The identification of bacillaene, the product of the PksX megacomplex in Bacillus subtilis

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-04900-7_4

Macrolactin is the Polyketide Biosynthesis Product of the pks2 Cluster of Bacillus amyloliquefaciens FZB42

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-04900-7_4

Genomics-inspired discovery of natural products

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-04900-7_4

Pathogenic fungus harbours endosymbiotic bacteria for toxin production

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-04900-7_4

Quorum-sensing control of antibiotic synthesis in Burkholderia thailandensis

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-04900-7_4

Quorum-sensing-regulated bactobolin production by Burkholderia thailandensis E264.

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-04900-7_4

Nitro versus hydroxamate in siderophores of pathogenic bacteria: effect of missing hydroxylamine protection in malleobactin biosynthesis.

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-04900-7_4

Structure and Biosynthetic Assembly of Cupriachelin, a Photoreactive Siderophore from the Bioplastic Producer Cupriavidus necator H16

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-04900-7_4

Gold biomineralization by a metallophore from a gold-associated microbe.

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-04900-7_4

Rapid Virulence Annotation (RVA): identification of virulence factors using a bacterial genome library and multiple invertebrate hosts

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-04900-7_4

Biosynthesis of a complex yersiniabactin-like natural product via the mic locus in phytopathogen Ralstonia solanacearum

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-04900-7_4

An iterative type I polyketide synthase initiates the biosynthesis of the antimycoplasma agent micacocidin

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-04900-7_4

Molecular genetic mining of the Aspergillus secondary metabolome: discovery of the emericellamide biosynthetic pathway

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-04900-7_4

Genome-based deletion analysis reveals the prenyl xanthone biosynthesis pathway in Aspergillus nidulans

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-04900-7_4

Two separate gene clusters encode the biosynthetic pathway for the meroterpenoids austinol and dehydroaustinol in Aspergillus nidulans.

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-04900-7_4

Biosynthetic pathway for the epipolythiodioxopiperazine acetylaranotin in Aspergillus terreus revealed by genome-based deletion analysis

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-04900-7_4

Regulation of fungal secondary metabolism

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-04900-7_4

Chromatin-level regulation of biosynthetic gene clusters

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-04900-7_4

Histone deacetylase activity regulates chemical diversity in Aspergillus

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-04900-7_4

Overexpression of the Aspergillus nidulans histone 4 acetyltransferase EsaA increases activation of secondary metabolite production

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-04900-7_4

Cytotoxic pheofungins from an engineered fungus impaired in posttranslational protein modification

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-04900-7_4

Molecular genetic characterization of the biosynthesis cluster of a prenylated isoindolinone alkaloid aspernidine A in Aspergillus nidulans

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-04900-7_4

Genomics-driven discovery of PKS-NRPS hybrid metabolites from Aspergillus nidulans

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-04900-7_4

A gene cluster containing two fungal polyketide synthases encodes the biosynthetic pathway for a polyketide, asperfuranone, in Aspergillus nidulans

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-04900-7_4

Genome mining of a prenylated and immunosuppressive polyketide from pathogenic fungi

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-04900-7_4

Activation of a silent fungal polyketide biosynthesis pathway through regulatory cross talk with a cryptic nonribosomal peptide synthetase gene cluster

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-04900-7_4

Comparative characterization of fungal anthracenone and naphthacenedione biosynthetic pathways reveals an α-hydroxylation-dependent Claisen-like cyclization catalyzed by a dimanganese thioesterase.

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-04900-7_4

Identification of csypyrone B1 as the novel product of Aspergillus oryzae type III polyketide synthase CsyB.

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-04900-7_4

Molecular genetic analysis reveals that a nonribosomal peptide synthetase-like (NRPS-like) gene in Aspergillus nidulans is responsible for microperfuranone biosynthesis

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-04900-7_4

Multifactorial induction of an orphan PKS-NRPS gene cluster in Aspergillus terreus

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-04900-7_4

The global virulence regulators VsrAD and PhcA control secondary metabolism in the plant pathogen Ralstonia solanacearum

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-04900-7_4

Ralfuranone biosynthesis in Ralstonia solanacearum suggests functional divergence in the quinone synthetase family of enzymes

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-04900-7_4

Induced Biosynthesis of Cryptic Polyketide Metabolites in a Burkholderia thailandensis Quorum Sensing Mutant

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-04900-7_4

Acyldepsipeptide HDAC inhibitor production induced in Burkholderia thailandensis

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-04900-7_4

Thailandepsins: bacterial products with potent histone deacetylase inhibitory activities and broad-spectrum antiproliferative activities.

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-04900-7_4

Genomics-driven discovery of burkholderic acid, a noncanonical, cryptic polyketide from human pathogenic Burkholderia species

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-04900-7_4

Malleilactone, a polyketide synthase-derived virulence factor encoded by the cryptic secondary metabolome of Burkholderia pseudomallei group pathogens.

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-04900-7_4

Characterization and manipulation of the pathway-specific late regulator AlpW reveals Streptomyces ambofaciens as a new producer of Kinamycins

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-04900-7_4

Identification of a bioactive 51-membered macrolide complex by activation of a silent polyketide synthase in Streptomyces ambofaciens

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-04900-7_4

Genome-based bioprospecting of microbes for new therapeutics.

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-04900-7_4

Metagenomic approaches to natural products from free-living and symbiotic organisms

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-04900-7_4

Genome mining to identify new plant triterpenoids

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-04900-7_4

Product profile of PEN3: the last unexamined oxidosqualene cyclase in Arabidopsis thaliana

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-04900-7_4

An effective strategy for exploring unknown metabolic pathways by genome mining.

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-04900-7_4

Data mining and characterization of a novel pediocin-like bacteriocin system from the genome of Pediococcus pentosaceus ATCC 25745.

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-04900-7_4

Precursor-centric genome-mining approach for lasso peptide discovery

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-04900-7_4

Isolation and structural characterization of capistruin, a lasso peptide predicted from the genome sequence of Burkholderia thailandensis E264.

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-04900-7_4

Ribosomal synthesis of tricyclic depsipeptides in bloom-forming cyanobacteria

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-04900-7_4

Exploiting the natural diversity of microviridin gene clusters for discovery of novel tricyclic depsipeptides

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-04900-7_4

Metagenome mining reveals polytheonamides as posttranslationally modified ribosomal peptides

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-04900-7_4

Collinone, a new recombinant angular polyketide antibiotic made by an engineered Streptomyces strain

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-04900-7_4

Artificial Reconstruction of Two Cryptic Angucycline Antibiotic Biosynthetic Pathways

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-04900-7_4

A genomic screening approach to the structure-guided identification of drug candidates from natural sources.

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-04900-7_4

Full-length RecE enhances linear-linear homologous recombination and facilitates direct cloning for bioprospecting.

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-04900-7_4

Reconstitution of a fungal meroterpenoid biosynthesis reveals the involvement of a novel family of terpene cyclases

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-04900-7_4

Genome mining in Streptomyces coelicolor: molecular cloning and characterization of a new sesquiterpene synthase

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-04900-7_4

A gene cluster for biosynthesis of the sesquiterpenoid antibiotic pentalenolactone in Streptomyces avermitilis

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-04900-7_4

Biosynthesis of the sesquiterpene antibiotic albaflavenone in Streptomyces coelicolor A3(2)

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-04900-7_4

Genome mining in Streptomyces avermitilis: A biochemical Baeyer-Villiger reaction and discovery of a new branch of the pentalenolactone family tree

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-04900-7_4

Expression and mechanistic analysis of a germacradienol synthase from Streptomyces coelicolor implicated in geosmin biosynthesis

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-04900-7_4

PCR-targeted Streptomyces gene replacement identifies a protein domain needed for biosynthesis of the sesquiterpene soil odor geosmin

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-04900-7_4

Biosynthesis of the earthy odorant geosmin by a bifunctional Streptomyces coelicolor enzyme

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-04900-7_4

Identification and functional analysis of genes controlling biosynthesis of 2-methylisoborneol

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-04900-7_4

Biochemistry and molecular genetics of the biosynthesis of the earthy odorant methylisoborneol in Streptomyces coelicolor

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-04900-7_4

Genome mining in Streptomyces avermitilis: cloning and characterization of SAV_76, the synthase for a new sesquiterpene, avermitilol

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-04900-7_4

Genome-minimized Streptomyces host for the heterologous expression of secondary metabolism

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-04900-7_4

Catalytic promiscuity in the biosynthesis of cyclic peptide secondary metabolites in planktonic marine cyanobacteria

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-04900-7_4

Discovery of unique lanthionine synthetases reveals new mechanistic and evolutionary insights

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-04900-7_4

Antibacterial discovery in actinomycetes strains with mutations in RNA polymerase or ribosomal protein S12.

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-04900-7_4

Structure and biosynthesis of the unusual polyketide alkaloid coelimycin P1, a metabolic product of the cpk gene cluster of Streptomyces coelicolor M145

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-04900-7_4

Engineering fungal secondary metabolism: a roadmap to novel compounds

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-04900-7_4

Recent advances in the heterologous expression of microbial natural product biosynthetic pathways

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-04900-7_4

Overexpressing transcriptional regulator in Aspergillus oryzae activates a silent biosynthetic pathway to produce a novel polyketide

31 March 2020

1 reference

9 March 2024

https://opencitations.net/index/api/v1/citations/10.1002/CBIC.201200107

Identifiers

DOI

10.1007/978-3-319-04900-7_4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25296440%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

1 reference