(Q47246914)

http://europepmc.org/abstract/MED/28967882

12 January 2018

title

Crystal structures of a GABAA-receptor chimera reveal new endogenous neurosteroid-binding sites (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6853794&resulttype=core&format=json

13 May 2020

1 reference

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6853794&resulttype=core&format=json

13 May 2020

Philip C. Biggin

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6853794&resulttype=core&format=json

13 May 2020

Marc Gielen

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6853794&resulttype=core&format=json

13 May 2020

Trevor G Smart

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6853794&resulttype=core&format=json

13 May 2020

author name string

Duncan Laverty

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6853794&resulttype=core&format=json

13 May 2020

Philip Thomas

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6853794&resulttype=core&format=json

13 May 2020

Martin Field

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6853794&resulttype=core&format=json

13 May 2020

Ole J Andersen

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6853794&resulttype=core&format=json

13 May 2020

publication date

2 October 2017

1 reference

http://europepmc.org/abstract/MED/28967882

12 January 2018

published in

Nature Structural & Molecular Biology

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6853794&resulttype=core&format=json

13 May 2020

volume

24

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6853794&resulttype=core&format=json

13 May 2020

issue

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6853794&resulttype=core&format=json

13 May 2020

page(s)

977-985

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6853794&resulttype=core&format=json

https://scigraph.springernature.com/pub.10.1038/nsmb.3477

13 May 2020

exact match

0 references

cites work

Binding, activation and modulation of Cys-loop receptors.

1 reference

Structure and pharmacology of pentameric receptor channels: from bacteria to brain

21 January 2018

1 reference

Variations on an inhibitory theme: phasic and tonic activation of GABA(A) receptors

21 January 2018

1 reference

The GABAA Receptor as a Therapeutic Target for Neurodevelopmental Disorders

21 January 2018

1 reference

GABAA receptor subtypes: Therapeutic potential in Down syndrome, affective disorders, schizophrenia, and autism

21 January 2018

1 reference

Distinguishing between GABA(A) receptors responsible for tonic and phasic conductances

21 January 2018

1 reference

Desensitized states prolong GABAA channel responses to brief agonist pulses.

21 January 2018

1 reference

Profound desensitization by ambient GABA limits activation of δ-containing GABAA receptors during spillover

21 January 2018

1 reference

The desensitization gate of inhibitory Cys-loop receptors.

21 January 2018

1 reference

Neurosteroids: endogenous regulators of the GABA(A) receptor

21 January 2018

1 reference

Formation and plasticity of GABAergic synapses: physiological mechanisms and pathophysiological implications.

21 January 2018

1 reference

Effect of the alpha subunit subtype on the macroscopic kinetic properties of recombinant GABA(A) receptors

21 January 2018

1 reference

Endogenous neurosteroids regulate GABAA receptors through two discrete transmembrane sites

21 January 2018

1 reference

General anaesthesia: from molecular targets to neuronal pathways of sleep and arousal

21 January 2018

1 reference

Making sense of nonsense GABA(A) receptor mutations associated with genetic epilepsies

21 January 2018

1 reference

Structure of a potentially open state of a proton-activated pentameric ligand-gated ion channel

21 January 2018

1 reference

X-ray structure of a pentameric ligand-gated ion channel in an apparently open conformation

21 January 2018

1 reference

Allosteric and hyperekplexic mutant phenotypes investigated on an α1 glycine receptor transmembrane structure

21 January 2018

1 reference

X-ray structures of general anaesthetics bound to a pentameric ligand-gated ion channel

21 January 2018

1 reference

Structural basis for potentiation by alcohols and anaesthetics in a ligand-gated ion channel

21 January 2018

1 reference

Structural basis for ion permeation mechanism in pentameric ligand-gated ion channels

21 January 2018

1 reference

Genuine open form of the pentameric ligand-gated ion channel GLIC.

21 January 2018

1 reference

Coupling of agonist binding to channel gating in the GABA(A) receptor

21 January 2018

1 reference

Role of the conserved lysine residue in the middle of the predicted extracellular loop between M2 and M3 in the GABA(A) receptor

21 January 2018

1 reference

An asymmetric contribution to gamma-aminobutyric type A receptor function of a conserved lysine within TM2-3 of alpha1, beta2, and gamma2 subunits

21 January 2018

1 reference

De novo GABRA1 mutations in Ohtahara and West syndromes

21 January 2018

1 reference

Principles of activation and permeation in an anion-selective Cys-loop receptor

21 January 2018

1 reference

Crystal structure of a human GABAA receptor

21 January 2018

1 reference

Glycine receptor mechanism elucidated by electron cryo-microscopy

21 January 2018

1 reference

Crystal structure of human glycine receptor-α3 bound to antagonist strychnine

21 January 2018

1 reference

A predicted binding site for cholesterol on the GABAA receptor

21 January 2018

1 reference

Neurotransmitter action: opening of ligand-gated ion channels

21 January 2018

1 reference

Crystal Structures of Human GlyRα3 Bound to Ivermectin.

21 January 2018

1 reference

Crystal structures of human glycine receptor α3 bound to a novel class of analgesic potentiators.

21 January 2018

1 reference

Desensitization mechanism in prokaryotic ligand-gated ion channel

21 January 2018

1 reference

Bridging the gap between structural models of nicotinic receptor superfamily ion channels and their corresponding functional states

21 January 2018

1 reference

X-ray structures of GluCl in apo states reveal a gating mechanism of Cys-loop receptors.

21 January 2018

1 reference

Sites of alcohol and volatile anaesthetic action on GABA(A) and glycine receptors.

21 January 2018

1 reference

Structural basis for alcohol modulation of a pentameric ligand-gated ion channel

21 January 2018

1 reference

Neurosteroid replacement therapy for catamenial epilepsy

21 January 2018

1 reference

A neurosteroid potentiation site can be moved among GABAA receptor subunits.

21 January 2018

1 reference

Neurosteroid analog photolabeling of a site in the third transmembrane domain of the β3 subunit of the GABA(A) receptor

21 January 2018

1 reference

Neurosteroid binding sites on GABA(A) receptors

21 January 2018

1 reference

Inhibitory neurosteroids and the GABAA receptor

21 January 2018

1 reference

Mutations of the GABA-A receptor alpha1 subunit M1 domain reveal unexpected complexity for modulation by neuroactive steroids.

21 January 2018

1 reference

Gating allosterism at a single class of etomidate sites on alpha1beta2gamma2L GABA A receptors accounts for both direct activation and agonist modulation

21 January 2018

1 reference

X-ray structure of the human α4β2 nicotinic receptor

21 January 2018

1 reference

Identification of a GABAA receptor anesthetic binding site at subunit interfaces by photolabeling with an etomidate analog.

21 January 2018

1 reference

Neurosteroids allosterically modulate binding of the anesthetic etomidate to gamma-aminobutyric acid type A receptors

21 January 2018

1 reference

A prokaryotic proton-gated ion channel from the nicotinic acetylcholine receptor family

21 January 2018

1 reference

21 January 2018

Decision making in xia2.

1 reference

Overview of the CCP4 suite and current developments

21 January 2018

1 reference

Phasercrystallographic software

21 January 2018

1 reference

The Buccaneer software for automated model building. 1. Tracing protein chains

21 January 2018

1 reference

Features and development of Coot

21 January 2018

1 reference

Iterative model building, structure refinement and density modification with the PHENIX AutoBuild wizard

21 January 2018

1 reference

MolProbity: all-atom structure validation for macromolecular crystallography

21 January 2018

1 reference

HOLE: a program for the analysis of the pore dimensions of ion channel structural models

21 January 2018

1 reference

PROMALS3D: multiple protein sequence alignment enhanced with evolutionary and three-dimensional structural information

21 January 2018

1 reference

Two WXXF-based motifs in NECAPs define the specificity of accessory protein binding to AP-1 and AP-2.

21 January 2018

1 reference

Comparative protein modelling by satisfaction of spatial restraints

21 January 2018

1 reference

LAMBADA and InflateGRO2: efficient membrane alignment and insertion of membrane proteins for molecular dynamics simulations.

21 January 2018

1 reference

ff14SB: Improving the Accuracy of Protein Side Chain and Backbone Parameters from ff99SB.

21 January 2018

1 reference

Lipid14: The Amber Lipid Force Field.

21 January 2018

1 reference

Numerical integration of the cartesian equations of motion of a system with constraints: molecular dynamics of n-alkanes

21 January 2018

1 reference

Particle mesh Ewald: An N⋅log(N) method for Ewald sums in large systems

21 January 2018

1 reference

PROPKA3: Consistent Treatment of Internal and Surface Residues in Empirical pKa Predictions

21 January 2018

1 reference

Identification of a beta subunit TM2 residue mediating proton modulation of GABA type A receptors.

21 January 2018

1 reference

Enantioselectivity of pregnanolone-induced gamma-aminobutyric acid(A) receptor modulation and anesthesia.

31 March 2020

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/28967882

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NSMB.3477

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6853794&resulttype=core&format=json

Dimensions Publication ID

13 May 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6853794&resulttype=core&format=json

13 May 2020

1 reference