(Q47353535)

14 January 2018

http://europepmc.org/abstract/MED/28355063

title

Quantitative Adverse Outcome Pathways and Their Application to Predictive Toxicology (English)

1 reference

14 January 2018

http://europepmc.org/abstract/MED/28355063

main subject

adverse outcome pathway

0 references

author

Rory B Conolly

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28355063%20AND%20SRC:MED&resulttype=core&format=json

3 June 2020

Gerald T Ankley

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28355063%20AND%20SRC:MED&resulttype=core&format=json

3 June 2020

Edward J Perkins

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28355063%20AND%20SRC:MED&resulttype=core&format=json

3 June 2020

Daniel L Villeneuve

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28355063%20AND%20SRC:MED&resulttype=core&format=json

3 June 2020

8

Karen H Watanabe

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28355063%20AND%20SRC:MED&resulttype=core&format=json

3 June 2020

5

David H Miller

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28355063%20AND%20SRC:MED&resulttype=core&format=json

3 June 2020

author name string

WanYun Cheng

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28355063%20AND%20SRC:MED&resulttype=core&format=json

3 June 2020

Michael L Mayo

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28355063%20AND%20SRC:MED&resulttype=core&format=json

3 June 2020

language of work or name

English

0 references

publication date

29 March 2017

1 reference

14 January 2018

http://europepmc.org/abstract/MED/28355063

published in

Environmental Science & Technology

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28355063%20AND%20SRC:MED&resulttype=core&format=json

3 June 2020

volume

51

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28355063%20AND%20SRC:MED&resulttype=core&format=json

3 June 2020

issue

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28355063%20AND%20SRC:MED&resulttype=core&format=json

3 June 2020

page(s)

4661-4672

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28355063%20AND%20SRC:MED&resulttype=core&format=json

How Adverse Outcome Pathways Can Aid the Development and Use of Computational Prediction Models for Regulatory Toxicology

3 June 2020

cites work

1 reference

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Editor's Highlight: Computational Modeling of Plasma Vitellogenin Alterations in Response to Aromatase Inhibition in Fathead Minnows

29 September 2018

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ToxCast Chemical Landscape: Paving the Road to 21st Century Toxicology

29 September 2018

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A Computational Model of the Rainbow Trout Hypothalamus-Pituitary-Ovary-Liver Axis

29 September 2018

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Computational model of the fathead minnow hypothalamic-pituitary-gonadal axis: Incorporating protein synthesis in improving predictability of responses to endocrine active chemicals

29 September 2018

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Predicting Fecundity of Fathead Minnows (Pimephales promelas) Exposed to Endocrine-Disrupting Chemicals Using a MATLAB®-Based Model of Oocyte Growth Dynamics

29 September 2018

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Linking mechanistic toxicology to population models in forecasting recovery from chemical stress: A case study from Jackfish Bay, Ontario, Canada

29 September 2018

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Increasing Scientific Confidence in Adverse Outcome Pathways: Application of Tailored Bradford-Hill Considerations for Evaluating Weight of Evidence

29 September 2018

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Temporal changes in biological responses and uncertainty in assessing risks of endocrine-disrupting chemicals: insights from intensive time-course studies with fish

29 September 2018

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Adverse outcome pathway development II: best practices.

29 September 2018

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Adverse outcome pathway (AOP) development I: strategies and principles

29 September 2018

1 reference

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Application of mass balance models and the chemical activity concept to facilitate the use of in vitro toxicity data for risk assessment.

29 September 2018

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Identification of parameter correlations for parameter estimation in dynamic biological models.

29 September 2018

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Simultaneous model discrimination and parameter estimation in dynamic models of cellular systems

29 September 2018

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Assessment of status of white sucker (Catostomus commersoni) populations exposed to bleached kraft pulp mill effluent

29 September 2018

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Developing predictive approaches to characterize adaptive responses of the reproductive endocrine axis to aromatase inhibition: I. Data generation in a small fish model

29 September 2018

1 reference

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Developing predictive approaches to characterize adaptive responses of the reproductive endocrine axis to aromatase inhibition: II. Computational modeling

29 September 2018

1 reference

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A time-course analysis of effects of the steroidogenesis inhibitor ketoconazole on components of the hypothalamic-pituitary-gonadal axis of fathead minnows

29 September 2018

1 reference

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A graphical systems model and tissue-specific functional gene sets to aid transcriptomic analysis of chemical impacts on the female teleost reproductive axis

29 September 2018

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Physiologically based pharmacokinetic model use in risk assessment--Why being published is not enough.

29 September 2018

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Gonadal histology and characteristic histopathology associated with endocrine disruption in the adult fathead minnow (Pimephales promelas).

29 September 2018

1 reference

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Effect of endocrine disruptor pesticides: a review

29 September 2018

1 reference

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A computational model of the hypothalamic: pituitary: gonadal axis in female fathead minnows (Pimephales promelas) exposed to 17α-ethynylestradiol and 17β-trenbolone

29 September 2018

1 reference

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Adverse outcome pathways: A conceptual framework to support ecotoxicology research and risk assessment

29 September 2018

1 reference

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Fathead minnow steroidogenesis: in silico analyses reveals tradeoffs between nominal target efficacy and robustness to cross-talk

29 September 2018

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29 September 2018

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What role for biologically based dose-response models in estimating low-dose risk?

29 September 2018

1 reference

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Dynamic nature of alterations in the endocrine system of fathead minnows exposed to the fungicide prochloraz

29 September 2018

1 reference

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Direct effects, compensation, and recovery in female fathead minnows exposed to a model aromatase inhibitor

29 September 2018

1 reference

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A computational model of the hypothalamic-pituitary-gonadal axis in male fathead minnows exposed to 17alpha-ethinylestradiol and 17beta-estradiol

29 September 2018

1 reference

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Relationship of plasma sex steroid concentrations in female fathead minnows to reproductive success and population status

29 September 2018

1 reference

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Ketoconazole in the fathead minnow (Pimephales promelas): reproductive toxicity and biological compensation.

29 September 2018

1 reference

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Linkage of biochemical responses to population-level effects: a case study with vitellogenin in the fathead minnow (Pimephales promelas).

29 September 2018

1 reference

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Effects of two fungicides with multiple modes of action on reproductive endocrine function in the fathead minnow (Pimephales promelas).

29 September 2018

1 reference

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Modeling impacts on populations: fathead minnow (Pimephales promelas) exposure to the endocrine disruptor 17beta-trenbolone as a case study

29 September 2018

1 reference

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Human respiratory tract cancer risks of inhaled formaldehyde: dose-response predictions derived from biologically-motivated computational modeling of a combined rodent and human dataset

29 September 2018

1 reference

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Modeling cell signaling networks

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6134852

Evaluation of the aromatase inhibitor fadrozole in a short-term reproduction assay with the fathead minnow (Pimephales promelas).

29 September 2018

1 reference

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Description and evaluation of a short-term reproduction test with the fathead minnow (Pimephales promelas).

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6134852

Evaluation of biologically based dose-response modeling for developmental toxicity: a workshop report.

29 September 2018

1 reference

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Hazard and risk assessment of chemical mixtures using the toxic equivalency factor approach

29 September 2018

1 reference

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29 September 2018

Identifiers

DOI

10.1021/ACS.EST.6B06230

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28355063%20AND%20SRC:MED&resulttype=core&format=json

3 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28355063%20AND%20SRC:MED&resulttype=core&format=json

3 June 2020

1 reference