(Q47412326)

15 January 2018

title

Increased cell size and Akt activation in HER-2/neu-overexpressing invasive ductal carcinoma of the breast (English)

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15 January 2018

invasive ductal carcinoma

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12

Vincent-Salomon A

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1

Sastre-Garau X

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15 January 2018

author name string

Genin P

2

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Rousseau A

3

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Al Ghuzlan A

4

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Nicolas A

5

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Fréneaux P

6

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Rosty C

7

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Sigal-Zafrani B

8

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Couturier J

9

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Thiery JP

10

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Magdelénat H

11

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publication date

1 August 2004

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15 January 2018

published in

Histopathology

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volume

45

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issue

2

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page(s)

142-147

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15 January 2018

Strong correlation between results of fluorescent in situ hybridization and immunohistochemistry for the assessment of the ERBB2 (HER-2/neu) gene status in breast carcinoma

cites work

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2559.2004.01899.X

Use of chemotherapy plus a monoclonal antibody against HER2 for metastatic breast cancer that overexpresses HER2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2559.2004.01899.X

Unraveling resistance to trastuzumab (Herceptin): insulin-like growth factor-I receptor, a new suspect.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2559.2004.01899.X

HER-2/neu blocks tumor necrosis factor-induced apoptosis via the Akt/NF-kappaB pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2559.2004.01899.X

Akt maintains cell size and survival by increasing mTOR-dependent nutrient uptake

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2559.2004.01899.X

AKT1/PKBalpha kinase is frequently elevated in human cancers and its constitutive activation is required for oncogenic transformation in NIH3T3 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2559.2004.01899.X

Coordination of cell growth with cell division

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2559.2004.01899.X

Extracellular control of cell size

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2559.2004.01899.X

Size control: cell proliferation does not equal growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2559.2004.01899.X

The role of c-myc in cellular growth control

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2559.2004.01899.X

Control of cell growth by c-Myc in the absence of cell division

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2559.2004.01899.X

Regulation of cell size in growth, development and human disease: PI3K, PKB and S6K.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2559.2004.01899.X

Essential role of PDK1 in regulating cell size and development in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2559.2004.01899.X

Regulation of pancreatic beta-cell growth and survival by the serine/threonine protein kinase Akt1/PKBalpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2559.2004.01899.X

Cell-autonomous regulation of cell and organ growth in Drosophila by Akt/PKB.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2559.2004.01899.X

Cellular survival: a play in three Akts

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2559.2004.01899.X

The regulation and activities of the multifunctional serine/threonine kinase Akt/PKB.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2559.2004.01899.X

Protein kinase B localization and activation differentially affect S6 kinase 1 activity and eukaryotic translation initiation factor 4E-binding protein 1 phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2559.2004.01899.X

Cytoplasmic localization of p21Cip1/WAF1 by Akt-induced phosphorylation in HER-2/neu-overexpressing cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2559.2004.01899.X

PKB/Akt phosphorylates p27, impairs nuclear import of p27 and opposes p27-mediated G1 arrest

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2559.2004.01899.X

PKB/Akt mediates cell-cycle progression by phosphorylation of p27(Kip1) at threonine 157 and modulation of its cellular localization

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2559.2004.01899.X

Cytoplasmic relocalization and inhibition of the cyclin-dependent kinase inhibitor p27(Kip1) by PKB/Akt-mediated phosphorylation in breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2559.2004.01899.X

AKT2 is frequently upregulated in HER-2/neu-positive breast cancers and may contribute to tumor aggressiveness by enhancing cell survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2559.2004.01899.X

10.1111/J.1365-2559.2004.01899.X

21 January 2018

Identifiers

DOI

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15 January 2018

1 reference

15 January 2018