(Q47443248)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29101163%20AND%20SRC:MED&resulttype=core&format=json

8 April 2020

title

CDK4/6 Inhibition Augments Antitumor Immunity by Enhancing T-cell Activation (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29101163%20AND%20SRC:MED&resulttype=core&format=json

8 April 2020

1

1 reference

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8 April 2020

Ruben Dries

5

1 reference

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8 April 2020

Kathy F Yates

6

1 reference

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8 April 2020

Sandeep Chhabra

7

1 reference

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8 April 2020

Patrick H Lizotte

18

1 reference

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8 April 2020

Ting Chen

26

1 reference

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8 April 2020

Haribabu Arthanari

43

1 reference

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8 April 2020

Kwok Kin Wong

47

1 reference

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8 April 2020

46

Nathanael S Gray

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29101163%20AND%20SRC:MED&resulttype=core&format=json

8 April 2020

41

W Nicholas Haining

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29101163%20AND%20SRC:MED&resulttype=core&format=json

8 April 2020

45

David A Barbie

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29101163%20AND%20SRC:MED&resulttype=core&format=json

8 April 2020

Russell William Jenkins

3

object named as

Russell W Jenkins

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29101163%20AND%20SRC:MED&resulttype=core&format=json

8 April 2020

39

Gordon J Freeman

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29101163%20AND%20SRC:MED&resulttype=core&format=json

8 April 2020

40

Jerome Ritz

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29101163%20AND%20SRC:MED&resulttype=core&format=json

8 April 2020

author name string

Eric S Wang

2

1 reference

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8 April 2020

Shuai Li

4

1 reference

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8 April 2020

Wei Huang

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29101163%20AND%20SRC:MED&resulttype=core&format=json

8 April 2020

Hongye Liu

9

1 reference

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8 April 2020

Amir R Aref

10

1 reference

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8 April 2020

Elena Ivanova

11

1 reference

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8 April 2020

Michaela Bowden

13

1 reference

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8 April 2020

Chensheng W Zhou

14

1 reference

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8 April 2020

Grit S Herter-Sprie

15

1 reference

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8 April 2020

Jessica A Sorrentino

16

1 reference

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8 April 2020

John E Bisi

17

1 reference

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8 April 2020

Ashley A Merlino

19

1 reference

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8 April 2020

Max M Quinn

20

1 reference

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8 April 2020

Lauren E Bufe

21

1 reference

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8 April 2020

Annan Yang

22

1 reference

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8 April 2020

Yanxi Zhang

23

1 reference

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8 April 2020

Hua Zhang

24

1 reference

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8 April 2020

Peng Gao

25

1 reference

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8 April 2020

Megan E Cavanaugh

27

1 reference

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8 April 2020

Amanda J Rode

28

1 reference

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8 April 2020

Eric Haines

29

1 reference

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8 April 2020

Patrick J Roberts

30

1 reference

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8 April 2020

Jay C Strum

31

1 reference

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8 April 2020

William G Richards

32

1 reference

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8 April 2020

Jochen H Lorch

33

1 reference

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8 April 2020

Sareh Parangi

34

1 reference

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8 April 2020

Viswanath Gunda

35

1 reference

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8 April 2020

Genevieve M Boland

36

1 reference

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8 April 2020

Raphael Bueno

37

1 reference

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8 April 2020

Sangeetha Palakurthi

38

1 reference

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8 April 2020

Norman E Sharpless

42

1 reference

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8 April 2020

Geoffrey I Shapiro

44

1 reference

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8 April 2020

Cloud P Paweletz

12

1 reference

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8 April 2020

publication date

3 November 2017

1 reference

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8 April 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29101163%20AND%20SRC:MED&resulttype=core&format=json

8 April 2020

volume

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29101163%20AND%20SRC:MED&resulttype=core&format=json

8 April 2020

issue

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29101163%20AND%20SRC:MED&resulttype=core&format=json

8 April 2020

page(s)

216-233

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29101163%20AND%20SRC:MED&resulttype=core&format=json

Ex Vivo Profiling of PD-1 Blockade Using Organotypic Tumor Spheroids.

8 April 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5809273

Transient CDK4/6 inhibition protects hematopoietic stem cells from chemotherapy-induced exhaustion.

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5809273

Transcriptional Landscape of Human Tissue Lymphocytes Unveils Uniqueness of Tumor-Infiltrating T Regulatory Cells.

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5809273

Mutational landscape of EGFR-, MYC-, and Kras-driven genetically engineered mouse models of lung adenocarcinoma

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5809273

A Phase I Study of the Cyclin-Dependent Kinase 4/6 Inhibitor Ribociclib (LEE011) in Patients with Advanced Solid Tumors and Lymphomas

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5809273

A Kinase-Independent Function of CDK6 Links the Cell Cycle to Tumor Angiogenesis.

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5809273

CXCL16-positive dendritic cells enhance invariant natural killer T cell-dependent IFNγ production and tumor control

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5809273

Near-optimal probabilistic RNA-seq quantification

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5809273

MAP Kinase Inhibition Promotes T Cell and Anti-tumor Activity in Combination with PD-L1 Checkpoint Blockade

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5809273

Differential analyses for RNA-seq: transcript-level estimates improve gene-level inferences

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5809273

Adaptive resistance to therapeutic PD-1 blockade is associated with upregulation of alternative immune checkpoints.

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5809273

Preclinical Characterization of G1T28: A Novel CDK4/6 Inhibitor for Reduction of Chemotherapy-Induced Myelosuppression

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5809273

Epigenetic silencing of TH1-type chemokines shapes tumour immunity and immunotherapy

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5809273

Nivolumab versus Docetaxel in Advanced Nonsquamous Non-Small-Cell Lung Cancer

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5809273

Combination cancer immunotherapy and new immunomodulatory targets

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5809273

Big opportunities for small molecules in immuno-oncology

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5809273

A Threshold Level of Intratumor CD8+ T-cell PD1 Expression Dictates Therapeutic Response to Anti-PD1.

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5809273

Computational assignment of cell-cycle stage from single-cell transcriptome data

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5809273

Pembrolizumab versus Ipilimumab in Advanced Melanoma

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5809273

Immune checkpoint targeting in cancer therapy: toward combination strategies with curative potential

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5809273

Neoantigens in cancer immunotherapy.

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5809273

Cancer immunology. Mutational landscape determines sensitivity to PD-1 blockade in non-small cell lung cancer

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5809273

The transcription factor NFAT promotes exhaustion of activated CD8⁺ T cells.

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5809273

The history and future of targeting cyclin-dependent kinases in cancer therapy

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5809273

CDK6 as a key regulator of hematopoietic and leukemic stem cell activation

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5809273

Palbociclib: an evidence-based review of its potential in the treatment of breast cancer

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5809273

Normalization of RNA-seq data using factor analysis of control genes or samples

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5809273

Acquired and intrinsic resistance in cancer immunotherapy

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5809273

New roles for cyclin-dependent kinases in T cell biology: linking cell division and differentiation.

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5809273

Molecular and transcriptional basis of CD4⁺ T cell dysfunction during chronic infection

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5809273

Cyclin-dependent kinase 6 is a chromatin-bound cofactor for NF-κB-dependent gene expression.

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5809273

The intersection of immune-directed and molecularly targeted therapy in advanced melanoma: where we have been, are, and will be.

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5809273

Activation of the PD-1 pathway contributes to immune escape in EGFR-driven lung tumors

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5809273

Dual blockade of PD-1 and CTLA-4 combined with tumor vaccine effectively restores T-cell rejection function in tumors.

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5809273

Cyclin-dependent kinase 6 phosphorylates NF-κB P65 at serine 536 and contributes to the regulation of inflammatory gene expression

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5809273

STAR: ultrafast universal RNA-seq aligner

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5809273

The blockade of immune checkpoints in cancer immunotherapy

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5809273

A murine lung cancer co-clinical trial identifies genetic modifiers of therapeutic response

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5809273

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5809273

A systematic screen for CDK4/6 substrates links FOXM1 phosphorylation to senescence suppression in cancer cells

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5809273

Adoptive T cell therapy promotes the emergence of genomically altered tumor escape variants

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5809273

Asymmetric proteasome segregation as a mechanism for unequal partitioning of the transcription factor T-bet during T lymphocyte division

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5809273

Transcriptional analysis of HIV-specific CD8+ T cells shows that PD-1 inhibits T cell function by upregulating BATF

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5809273

A synthetic lethal interaction between K-Ras oncogenes and Cdk4 unveils a therapeutic strategy for non-small cell lung carcinoma.

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5809273

Phase I study of single-agent anti-programmed death-1 (MDX-1106) in refractory solid tumors: safety, clinical activity, pharmacodynamics, and immunologic correlates

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5809273

Tumor-associated lymphocytes as an independent predictor of response to neoadjuvant chemotherapy in breast cancer.

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5809273

IL-6 and Stat3 are required for survival of intestinal epithelial cells and development of colitis-associated cancer

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5809273

Antigenic experience dictates functional role of glycogen synthase kinase-3 in human CD4+ T cell responses

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5809273

The transcription factor EGR1 controls both the proliferation and localization of hematopoietic stem cells

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5809273

NFAT proteins: key regulators of T-cell development and function

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5809273

A small molecule-kinase interaction map for clinical kinase inhibitors

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5809273

Cancer regression and autoimmunity induced by cytotoxic T lymphocyte-associated antigen 4 blockade in patients with metastatic melanoma

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5809273

Tumor-associated B7-H1 promotes T-cell apoptosis: a potential mechanism of immune evasion

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5809273

Gene expression elicited by NFAT in the presence or absence of cooperative recruitment of Fos and Jun.

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5809273

Negative regulation of T cell proliferation and interleukin 2 production by the serine threonine kinase GSK-3

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5809273

Random-coil chemical shifts of phosphorylated amino acids.

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5809273

Identification of amino acid residues and protein kinases involved in the regulation of NFATc subcellular localization

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5809273

Development of lupus-like autoimmune diseases by disruption of the PD-1 gene encoding an ITIM motif-carrying immunoreceptor

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5809273

Direct effects of phosphorylation on the preferred backbone conformation of peptides: a nuclear magnetic resonance study

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5809273

Enhancement of antitumor immunity by CTLA-4 blockade

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5809273

10.1158/2159-8290.CD-17-0915

26 August 2018

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29101163%20AND%20SRC:MED&resulttype=core&format=json

8 April 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29101163%20AND%20SRC:MED&resulttype=core&format=json

8 April 2020

PubMed publication ID

29101163

1 reference