(Q47567374)

4 February 2018

title

New hope for Alzheimer disease vaccine (English)

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4 February 2018

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1

Christian Haass

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language of work or name

English

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publication date

1 November 2002

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4 February 2018

published in

Nature Medicine

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4 February 2018

volume

8

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4 February 2018

issue

11

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4 February 2018

page(s)

1195-1196

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4 February 2018

https://scigraph.springernature.com/pub.10.1038/nm1102-1195

exact match

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cites work

Generation of antibodies specific for beta-amyloid by vaccination of patients with Alzheimer disease.

1 reference

https://api.crossref.org/works/10.1038%2FNM1102-1195

Therapeutically effective antibodies against amyloid-beta peptide target amyloid-beta residues 4-10 and inhibit cytotoxicity and fibrillogenesis.

21 January 2018

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https://api.crossref.org/works/10.1038%2FNM1102-1195

Nerve inflammation halts trial for Alzheimer's drug.

21 January 2018

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https://api.crossref.org/works/10.1038%2FNM1102-1195

Naturally secreted oligomers of amyloid beta protein potently inhibit hippocampal long-term potentiation in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNM1102-1195

Identification of signal peptide peptidase, a presenilin-type aspartic protease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNM1102-1195

BACE1 is the major beta-secretase for generation of Abeta peptides by neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNM1102-1195

Mice deficient in BACE1, the Alzheimer's beta-secretase, have normal phenotype and abolished beta-amyloid generation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNM1102-1195

Immunization with amyloid-beta attenuates Alzheimer-disease-like pathology in the PDAPP mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNM1102-1195

Peripherally administered antibodies against amyloid beta-peptide enter the central nervous system and reduce pathology in a mouse model of Alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNM1102-1195

Peripheral anti-A beta antibody alters CNS and plasma A beta clearance and decreases brain A beta burden in a mouse model of Alzheimer's disease

21 January 2018

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https://api.crossref.org/works/10.1038%2FNM1102-1195

Disaggregation of Alzheimer beta-amyloid by site-directed mAb.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNM1102-1195

A beta peptide vaccination prevents memory loss in an animal model of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNM1102-1195

A beta peptide immunization reduces behavioural impairment and plaques in a model of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNM1102-1195

Predicting the failure of amyloid-beta vaccine.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNM1102-1195

21 January 2018

Identifiers

DOI

10.1038/NM1102-1195

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4 February 2018

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4 February 2018