(Q47591395)

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Protection of murine neural progenitor cells by the Hsp90 inhibitor 17-allylamino-17-demethoxygeldanamycin in the low nanomolar concentration range

scientific article published on 6 April 2011

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scholarly article

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Europe PubMed Central

PubMed publication ID

4 February 2018

http://europepmc.org/abstract/MED/21395580

Protection of murine neural progenitor cells by the Hsp90 inhibitor 17-allylamino-17-demethoxygeldanamycin in the low nanomolar concentration range (English)

1 reference

Europe PubMed Central

PubMed publication ID

4 February 2018

http://europepmc.org/abstract/MED/21395580

author name string

Guanghu Wang

1

1 reference

Europe PubMed Central

PubMed publication ID

4 February 2018

http://europepmc.org/abstract/MED/21395580

Kannan Krishnamurthy

2

1 reference

Europe PubMed Central

PubMed publication ID

4 February 2018

http://europepmc.org/abstract/MED/21395580

Dantera Tangpisuthipongsa

3

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Europe PubMed Central

PubMed publication ID

4 February 2018

http://europepmc.org/abstract/MED/21395580

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publication date

6 April 2011

1 reference

Europe PubMed Central

PubMed publication ID

4 February 2018

http://europepmc.org/abstract/MED/21395580

number of pages

9

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Journal of Neurochemistry

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Europe PubMed Central

PubMed publication ID

4 February 2018

http://europepmc.org/abstract/MED/21395580

117

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Europe PubMed Central

PubMed publication ID

4 February 2018

http://europepmc.org/abstract/MED/21395580

4

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Europe PubMed Central

PubMed publication ID

4 February 2018

http://europepmc.org/abstract/MED/21395580

703-711

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Europe PubMed Central

PubMed publication ID

4 February 2018

http://europepmc.org/abstract/MED/21395580

Glycogen synthase kinase-3 in neurodegeneration and neuroprotection: lessons from lithium

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Glycogen synthase kinase 3: a drug target for CNS therapies

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Regulation of cell death in mitotic neural progenitor cells by asymmetric distribution of prostate apoptosis response 4 (PAR-4) and simultaneous elevation of endogenous ceramide

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Selective apoptosis of pluripotent mouse and human stem cells by novel ceramide analogues prevents teratoma formation and enriches for neural precursors in ES cell-derived neural transplants

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Biological stress response terminology: Integrating the concepts of adaptive response and preconditioning stress within a hormetic dose-response framework

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Involvement of oxidative stress-induced abnormalities in ceramide and cholesterol metabolism in brain aging and Alzheimer's disease

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Chemotherapy for the brain: the antitumor antibiotic mithramycin prolongs survival in a mouse model of Huntington's disease

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Stress response in mesoangioblast stem cells.

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Adult stem cell therapy in stroke

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Hsp90 inhibition transiently activates Src kinase and promotes Src-dependent Akt and Erk activation

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Geldanamycin protects rat brain through overexpression of HSP70 and reducing brain edema after cerebral focal ischemia.

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Targeted mutation of the DNA methyltransferase gene results in embryonic lethality

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Critical issues of clinical human embryonic stem cell therapy for brain repair

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Stem cells in human neurodegenerative disorders--time for clinical translation?

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Increased "vigilance" of antioxidant mechanisms in neural stem cells potentiates their capability to resist oxidative stress

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Hormesis defined

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Heat shock-induced enhancement of osteoblastic differentiation of hTERT-immortalized mesenchymal stem cells

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Mechanisms of hormesis through mild heat stress on human cells.

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Inhibition of mTOR induces autophagy and reduces toxicity of polyglutamine expansions in fly and mouse models of Huntington disease

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Astroglial expression of ceramide in Alzheimer's disease brains: a role during neuronal apoptosis.

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Combining growth factor and stem cell therapy for amyotrophic lateral sclerosis

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Constantly updated knowledge of Hsp90.

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Amyloidosis and neurodegenerative diseases: current treatments and new pharmacological options

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Targeted disruption of the heat shock transcription factor (hsf)‐2 gene results in increased embryonic lethality, neuronal defects, and reduced spermatogenesis

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Direct binding to ceramide activates protein kinase Czeta before the formation of a pro-apoptotic complex with PAR-4 in differentiating stem cells

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A novel isoform of prostate apoptosis response 4 (PAR-4) that co-distributes with F-actin and prevents apoptosis in neural stem cells

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Long-chain ceramide is elevated in presenilin 1 (PS1M146V) mouse brain and induces apoptosis in PS1 astrocytes

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17-AAG, an Hsp90 inhibitor, ameliorates polyglutamine-mediated motor neuron degeneration

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Modulation of Hsp90 function in neurodegenerative disorders: a molecular-targeted therapy against disease-causing protein

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Dual inhibitory roles of geldanamycin on the c-Jun NH2-terminal kinase 3 signal pathway through suppressing the expression of mixed-lineage kinase 3 and attenuating the activation of apoptosis signal-regulating kinase 1 via facilitating the activati

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Inhibition of Hsp90 activates osteoclast c-Src signaling and promotes growth of prostate carcinoma cells in bone

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Identifiers

10.1111/J.1471-4159.2011.07239.X

1 reference

Europe PubMed Central

PubMed publication ID

4 February 2018

http://europepmc.org/abstract/MED/21395580

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

4 February 2018

http://europepmc.org/abstract/MED/21395580

ResearchGate publication ID

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