(Q47660988)

4 February 2018

title

An oncolytic adenoviral vector of Smac increases antitumor activity of TRAIL against HCC in human cells and in mice (English)

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4 February 2018

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hepatocellular carcinoma

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Zifei Pei

1

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4 February 2018

Liang Chu

2

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4 February 2018

Weiguo Zou

3

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4 February 2018

Zilai Zhang

4

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4 February 2018

Songbo Qiu

5

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4 February 2018

Rong Qi

6

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4 February 2018

Jinfa Gu

7

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4 February 2018

Cheng Qian

8

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4 February 2018

Xinyuan Liu

9

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4 February 2018

language of work or name

English

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publication date

1 May 2004

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4 February 2018

number of pages

11

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inferred from page(s)

published in

Hepatology

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4 February 2018

volume

39

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4 February 2018

issue

5

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4 February 2018

page(s)

1371-1381

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4 February 2018

Tumoricidal activity of tumor necrosis factor-related apoptosis-inducing ligand in vivo.

cites work

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7 January 2021

Safety and antitumor activity of recombinant soluble Apo2 ligand

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7 January 2021

Apoptosis control by death and decoy receptors

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7 January 2021

Apo2L/TRAIL-dependent recruitment of endogenous FADD and caspase-8 to death receptors 4 and 5.

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7 January 2021

Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis

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7 January 2021

IAP family proteins--suppressors of apoptosis

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7 January 2021

Structural basis of caspase-7 inhibition by XIAP

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7 January 2021

X-linked inhibitor of apoptosis protein (XIAP) inhibits caspase-3 and -7 in distinct modes

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7 January 2021

A novel anti-apoptosis gene, survivin, expressed in cancer and lymphoma

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7 January 2021

Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition

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7 January 2021

Identification of DIABLO, a mammalian protein that promotes apoptosis by binding to and antagonizing IAP proteins

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7 January 2021

A conserved XIAP-interaction motif in caspase-9 and Smac/DIABLO regulates caspase activity and apoptosis

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7 January 2021

The N-end rule: functions, mysteries, uses

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7 January 2021

Degradation of DIAP1 by the N-end rule pathway is essential for regulating apoptosis.

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7 January 2021

Omi/HtrA2 catalytic cleavage of inhibitor of apoptosis (IAP) irreversibly inactivates IAPs and facilitates caspase activity in apoptosis

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7 January 2021

Ubiquitin protein ligase activity of IAPs and their degradation in proteasomes in response to apoptotic stimuli

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7 January 2021

TRAIL-induced apoptosis requires Bax-dependent mitochondrial release of Smac/DIABLO.

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7 January 2021

Ectopic overexpression of second mitochondria-derived activator of caspases (Smac/DIABLO) or cotreatment with N-terminus of Smac/DIABLO peptide potentiates epothilone B derivative-(BMS 247550) and Apo-2L/TRAIL-induced apoptosis

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7 January 2021

Smac agonists sensitize for Apo2L/TRAIL- or anticancer drug-induced apoptosis and induce regression of malignant glioma in vivo.

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7 January 2021

Chemotherapeutic agents augment TRAIL-induced apoptosis in human hepatocellular carcinoma cell lines

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7 January 2021

An armed oncolytic adenovirus system, ZD55-gene, demonstrating potent antitumoral efficacy

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7 January 2021

Mad-overexpression down regulates the malignant growth and p53 mediated apoptosis in human hepatocellular carcinoma BEL-7404 cells

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7 January 2021

Identification and inhibition of the ICE/CED-3 protease necessary for mammalian apoptosis

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7 January 2021

Structural basis of IAP recognition by Smac/DIABLO

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7 January 2021

Apoptosis-associated release of Smac/DIABLO from mitochondria requires active caspases and is blocked by Bcl-2

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7 January 2021

Bcl-2 family proteins

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7 January 2021

Cancer gene therapy: fringe or cutting edge?

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7 January 2021

The potential of gene therapy in the treatment of hepatocellular carcinoma

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7 January 2021

New strategies to enhance gene therapy efficiency

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7 January 2021

Replication-selective virotherapy for cancer: Biological principles, risk management and future directions

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7 January 2021

An adenovirus mutant that replicates selectively in p53-deficient human tumor cells

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7 January 2021

a controlled trial of intratumoral ONYX-015, a selectively-replicating adenovirus, in combination with cisplatin and 5-fluorouracil in patients with recurrent head and neck cancer

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7 January 2021

Intra-arterial administration of a replication-selective adenovirus (dl1520) in patients with colorectal carcinoma metastatic to the liver: a phase I trial

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7 January 2021

Regulation of the cell cycle and apoptosis by the oncogenes of adenovirus

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7 January 2021

The role of adenovirus E4orf4 protein in viral replication and cell killing

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7 January 2021

A novel three-pronged approach to kill cancer cells selectively: concomitant viral, double suicide gene, and radiotherapy

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7 January 2021

Effective gene therapy for pancreatic cancer by cytokines mediated by restricted replication-competent adenovirus

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7 January 2021

Identifiers

DOI

10.1002/HEP.20203

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4 February 2018

PubMed ID

15122766

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4 February 2018