(Q47771685)

5 February 2018

review article

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title

A unifying hypothesis for the molecular mechanism of somatic mutation and gene conversion in rearranged immunoglobulin variable genes (English)

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5 February 2018

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Blanden RV

1

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5 February 2018

Steele EJ

series ordinal

2

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5 February 2018

publication date

1 June 1998

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5 February 2018

Immunology & Cell Biology

published in

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5 February 2018

volume

76

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5 February 2018

issue

3

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5 February 2018

page(s)

288-293

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5 February 2018

Somatic generation of antibody diversity

cites work

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.1998.00738.X

Mechanism of antigen-driven somatic hypermutation of rearranged immunoglobulin V(D)J genes in the mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.1998.00738.X

Hypothesis: somatic hypermutation by gene conversion via the error prone DNA----RNA----DNA information loop

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.1998.00738.X

Point mutations cause the somatic diversification of IgM and IgG2a antiphosphorylcholine antibodies

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.1998.00738.X

Analysis of somatic hypermutation in mouse Peyer's patches using immunoglobulin kappa light-chain transgenes

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.1998.00738.X

Discriminating intrinsic and antigen-selected mutational hotspots in immunoglobulin V genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.1998.00738.X

The efficiency of antibody affinity maturation: can the rate of B-cell division be limiting?

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.1998.00738.X

Boundaries of somatic mutation in rearranged immunoglobulin genes: 5' boundary is near the promoter, and 3' boundary is approximately 1 kb from V(D)J gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.1998.00738.X

Somatic hypermutation in 5' flanking regions of heavy chain antibody variable regions

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.1998.00738.X

The 5' boundary of somatic hypermutation in a V kappa gene is in the leader intron

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.1998.00738.X

Mapping the upstream boundary of somatic mutations in rearranged immunoglobulin transgenes and endogenous genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.1998.00738.X

Distribution of mutations around rearranged heavy-chain antibody variable-region genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.1998.00738.X

Somatic mutation in constant regions of mouse lambda 1 light chains

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.1998.00738.X

Defining the nucleic acid substrate for somatic hypermutation

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.1998.00738.X

The transcriptional promoter regulates hypermutation of the antibody heavy chain locus

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.1998.00738.X

Targeting of non-Ig sequences in place of the V segment by somatic hypermutation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.1998.00738.X

Somatic hypermutation of an immunoglobulin mu heavy chain transgene

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.1998.00738.X

Hypermutation is observed only in antibody H chain V region transgenes that have recombined with endogenous immunoglobulin H DNA: implications for the location of cis-acting elements required for somatic mutation

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.1998.00738.X

Analysis of a T cell receptor gene as a target of the somatic hypermutation mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.1998.00738.X

Analysis of sequence transfers resembling gene conversion in a mouse antibody transgene

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.1998.00738.X

Mutation in a reporter gene depends on proximity to and transcription of immunoglobulin variable transgenes

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.1998.00738.X

Reciprocal homologous recombination in or near antibody VDJ genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.1998.00738.X

Restricted VH gene usage and generation of antibody diversity in rabbit

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.1998.00738.X

Chicken IgL gene rearrangement involves deletion of a circular episome and addition of single nonrandom nucleotides to both coding segments.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.1998.00738.X

A hyperconversion mechanism generates the chicken light chain preimmune repertoire.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.1998.00738.X

10.1046/J.1440-1711.1998.00738.X

21 January 2018

Identifiers

DOI

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5 February 2018

1 reference

5 February 2018