(Q47911489)

6 February 2018

title

α-synuclein Induces Mitochondrial Dysfunction through Spectrin and the Actin Cytoskeleton (English)

1 reference

6 February 2018

Alpha Spectrin Dmel_CG1977

main subject

cytoskeleton

0 references

1 reference

Dynamin related protein 1 Dmel_CG3210

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

1 reference

Dalila G Ordonez

1

1 reference

6 February 2018

Michael K Lee

series ordinal

2

1 reference

6 February 2018

Mel B Feany

series ordinal

3

1 reference

6 February 2018

language of work or name

English

0 references

publication date

13 December 2017

1 reference

6 February 2018

published in

Neuron

1 reference

6 February 2018

volume

97

1 reference

6 February 2018

issue

1

1 reference

6 February 2018

page(s)

108-124.e6

1 reference

6 February 2018

describes a project that uses

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC5755717/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

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In Situ Peroxidase Labeling and Mass-Spectrometry Connects Alpha-Synuclein Directly to Endocytic Trafficking and mRNA Metabolism in Neurons

26 August 2018

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26 August 2018

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The Drosophila FHOD1-like formin Knittrig acts through Rok to promote stress fiber formation and directed macrophage migration during the cellular immune response

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Tau promotes neurodegeneration through global chromatin relaxation

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26 August 2018

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26 August 2018

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An antibody with high reactivity for disease-associated α-synuclein reveals extensive brain pathology

26 August 2018

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Spectrin-based skeleton as an actor in cell signaling

26 August 2018

1 reference

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Direct membrane association drives mitochondrial fission by the Parkinson disease-associated protein alpha-synuclein

26 August 2018

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26 August 2018

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26 August 2018

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Alpha-synuclein promotes SNARE-complex assembly in vivo and in vitro

26 August 2018

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26 August 2018

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Tyrosine and serine phosphorylation of alpha-synuclein have opposing effects on neurotoxicity and soluble oligomer formation

26 August 2018

1 reference

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Pre-fibrillar alpha-synuclein variants with impaired beta-structure increase neurotoxicity in Parkinson's disease models

26 August 2018

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{alpha}-synuclein and its A30P mutant affect actin cytoskeletal structure and dynamics

26 August 2018

1 reference

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Dynamic changes in presynaptic and axonal transport proteins combined with striatal neuroinflammation precede dopaminergic neuronal loss in a rat model of AAV alpha-synucleinopathy.

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5755717

Proteomics analysis identifies phosphorylation-dependent alpha-synuclein protein interactions

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5755717

Quantitative proteomics of a presymptomatic A53T alpha-synuclein Drosophila model of Parkinson disease

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5755717

Proteomic identification of novel proteins in cortical lewy bodies

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5755717

Aggregated alpha-synuclein mediates dopaminergic neurotoxicity in vivo.

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5755717

Evaluation of F-actin ELISA for the diagnosis of autoimmune hepatitis.

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5755717

Abnormal bundling and accumulation of F-actin mediates tau-induced neuronal degeneration in vivo.

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5755717

Selective fluorescent imaging of superoxide in vivo using ethidium-based probes

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5755717

Morphological alterations of the synapses in the locus coeruleus in Parkinson's disease

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5755717

TOR-mediated cell-cycle activation causes neurodegeneration in a Drosophila tauopathy model.

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5755717

Parkinson's disease alpha-synuclein transgenic mice develop neuronal mitochondrial degeneration and cell death.

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5755717

A systematic review of prevalence and incidence studies of dementia with Lewy bodies

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5755717

Diagnosis and management of dementia with Lewy bodies: third report of the DLB Consortium

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5755717

Synaptic mitochondria are critical for mobilization of reserve pool vesicles at Drosophila neuromuscular junctions

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5755717

Alpha-synuclein phosphorylation controls neurotoxicity and inclusion formation in a Drosophila model of Parkinson disease

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5755717

Staging of brain pathology related to sporadic Parkinson's disease

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5755717

Relative frequencies of Alzheimer disease, Lewy body, vascular and frontotemporal dementia, and hippocampal sclerosis in the State of Florida Brain Bank

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5755717

Human alpha-synuclein-harboring familial Parkinson's disease-linked Ala-53 --> Thr mutation causes neurodegenerative disease with alpha-synuclein aggregation in transgenic mice

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5755717

One of the two cytoplasmic actin isoforms in Drosophila is essential

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5755717

alpha-Synuclein is phosphorylated in synucleinopathy lesions

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5755717

Alpha-synuclein and neurodegenerative diseases

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5755717

Tauopathy in Drosophila: neurodegeneration without neurofibrillary tangles

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5755717

A Drosophila model of Parkinson's disease

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5755717

Dopaminergic loss and inclusion body formation in alpha-synuclein mice: implications for neurodegenerative disorders

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5755717

Genetic studies of spectrin: new life for a ghost protein.

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5755717

Mitochondrial complex I deficiency in Parkinson's disease

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5755717

MicroRNA and proteome expression profiling in early-symptomatic α-synuclein(A30P)-transgenic mice

26 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/29249285

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Mitochondrial dysfunction in Parkinson's disease

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/29249285

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.NEURON.2017.11.036

1 reference

6 February 2018

PMC publication ID

5755717

0 references

1 reference

6 February 2018